Search Results - "Wan, KangLin"

Southern East Asian origin and coexpansion of Mycobacterium tuberculosis Beijing family with Han Chinese by Luo, Tao, Iñaki Comas, Dan Luo, Bing Lu, Jie Wu, Lanhai Wei, Chongguang Yang, Qingyun Liu, Mingyu Gan, Gang Sun, Xin Shen, Feiying Liu, Sebastien Gagneux, Jian Mei, Rushu Lan, Kanglin Wan, Qian Gao

“…Significance Mycobacterium tuberculosis Beijing family is a group of globally emerging bacterial strains that are responsible for more than a quarter of the…”
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Efflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolates by Li, Guilian, Zhang, Jingrui, Guo, Qian, Jiang, Yi, Wei, Jianhao, Zhao, Li-li, Zhao, Xiuqin, Lu, Jianxin, Wan, Kanglin

“…Isoniazid (INH) and rifampicin (RIF) are the two most effective drugs in tuberculosis therapy. Understanding the molecular mechanisms of resistance to these…”
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Distribution of Borrelia burgdorferi Sensu Lato in China by Hao, Qin, Hou, Xuexia, Geng, Zhen, Wan, Kanglin

“…We genotyped 102 Borrelia burgdorferi sensu lato strains isolated from ticks, animals, and patients in 11 provinces in China by PCR-restriction fragment length…”
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Genome sequencing and analysis of BCG vaccine strains by Zhang, Wen, Zhang, Yuanyuan, Zheng, Huajun, Pan, Yuanlong, Liu, Haican, Du, Pengcheng, Wan, Li, Liu, Jun, Zhu, Baoli, Zhao, Guoping, Chen, Chen, Wan, Kanglin

“…Although the Bacillus Calmette-Guérin (BCG) vaccine against tuberculosis (TB) has been available for more than 75 years, one third of the world's population is…”
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Recombinant BCG vaccine expressing multistage antigens of Mycobacterium tuberculosis provides long-term immunity against tuberculosis in BALB/c mice by Fang, Danang, Wang, Ruihuan, Fan, Xueting, Li, Machao, Qian, Chenyu, Cao, Bin, Yu, Jinjie, Liu, Haican, Lou, Yongliang, Wan, Kanglin

“…Tuberculosis (TB) caused by (Mtb) persistently kills nearly 1.5 million lives per year in the world, whereas the only licensed TB vaccine BCG exhibits…”
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Ribokinase screened from T7 phage displayed Mycobacterium tuberculosis genomic DNA library had good potential for the serodiagnosis of tuberculosis by Luo, Dan, Wang, Li, Liu, Haican, Li, Lingling, Liao, Yating, Yi, Xiaomei, Yan, Xiaoliang, Wan, Kanglin, Zeng, Yanhua

“…Tuberculosis caused by Mycobacterium tuberculosis ( M. tuberculosis ) is the leading cause of death among infectious diseases in the worldwide. Lack of more…”
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A novel multistage antigens ERA005f confer protection against Mycobacterium tuberculosis by driving Th-1 and Th-17 type T cell immune responses by Fan, Xueting, Zhao, Xiuqin, Wang, Ruibai, Li, Machao, Luan, Xiuli, Wang, Ruihuan, Wan, Kanglin, Liu, Haican

“…Tuberculosis (TB) is a major threat to human health. In 2021, TB was the second leading cause of death after COVID-19 among infectious diseases. The Bacillus…”
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Trends in the Prevalence and Antibiotic Resistance of Non-tuberculous Mycobacteria in Mainland China, 2000-2019: Systematic Review and Meta-Analysis by Zhou, Lei, Xu, Da, Liu, Hancan, Wan, Kanglin, Wang, Ruibai, Yang, Zaichang

“…China is a high-burden country of tuberculosis. The proportion of diseases caused by non-tuberculous mycobacteria (NTM) has increased, seriously affecting the…”
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Drug Susceptibility Testing of 31 Antimicrobial Agents on Rapidly Growing Mycobacteria Isolates from China by Wan, Kanglin, Liu, Haican, Zhao, Xiuqin, Li, Guilian, Pang, Hui, Yu, Ping

“…Objectives. Several species of rapidly growing mycobacteria (RGM) are now recognized as human pathogens. However, limited data on effective drug treatments…”
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Drug Susceptibility of 33 Reference Strains of Slowly Growing Mycobacteria to 19 Antimicrobial Agents by Pang, Hui, Wan, Kanglin, Jiang, Yi

“…Objectives. Slowly growing mycobacteria (SGM) are prevalent worldwide and cause an extensive spectrum of diseases. Methods. In this study, the antimicrobial…”
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Identification of positively selected genes in Mycobacterium tuberculosis from southern Xinjiang Uygur autonomous region of China by Deng, Lele, Wang, Quan, Liu, Haican, Jiang, Yi, Xu, Miao, Xiang, Yu, Yang, Ting, Yang, Shuliu, Yan, Di, Li, Machao, Zhao, Lili, Zhao, Xiuqin, Wan, Kanglin, He, Guangxue, Mijiti, Xiaokaiti, Li, Guilian

“…Tuberculosis (TB), mainly caused by ( ), remains a serious public health problem. Increasing evidence supports that selective evolution is an important force…”
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Genomic Analysis Identifies Mutations Concerning Drug-Resistance and Beijing Genotype in Multidrug-Resistant Mycobacterium tuberculosis Isolated From China by Wan, Li, Liu, Haican, Li, Machao, Jiang, Yi, Zhao, Xiuqin, Liu, Zhiguang, Wan, Kanglin, Li, Guilian, Guan, Cha-xiang

“…Development of modern genomics provides us an effective method to understand the molecular mechanism of drug resistance and diagnose drug-resistant…”
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Mycolicibacterium baixiangningiae sp. nov. and Mycolicibacterium mengxianglii sp. nov., two new rapidly growing mycobacterial species by Cheng, Yanpeng, Lei, Wenjing, Wang, Xiaoxia, Tian, Zhi, Liu, Haican, Yang, Jing, Lu, Shan, Lai, Xin-He, Pu, Ji, Huang, Ying, Zhang, Sihui, Yang, Caixin, Lian, Xingxing, Bai, Yibo, Wan, Kanglin, Wang, Suping, Xu, Jianguo

“…Four bacterial strains (LJ126 /S18 and Z-34 /S20) recovered from faecal samples of Tibetan antelopes on the Qinghai-Tibet Plateau of China were analysed using…”
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Antimicrobial susceptibility of standard strains of nontuberculous mycobacteria by microplate Alamar Blue assay by Li, Guilian, Lian, Lu-Lu, Wan, Li, Zhang, Jingrui, Zhao, Xiuqin, Jiang, Yi, Zhao, Li-Li, Liu, Haican, Wan, Kanglin

“…In this study, 24 standard nontuberculous mycobacteria (NTM) species strains including 12 slowly growing mycobacteria strains and 12 rapidly growing…”
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A novel multi-component protein vaccine ECP001 containing a protein polypeptide antigen nPstS1 riching in T-cell epitopes showed good immunogenicity and protection in mice by Yu, Jinjie, Fan, Xueting, Luan, Xiuli, Wang, Ruihuan, Cao, Bin, Qian, Chengyu, Li, Guilian, Li, Machao, Zhao, Xiuqin, Liu, Haican, Wan, Kanglin, Yuan, Xiuqin

“…Tuberculosis (TB) is an infectious disease that seriously affects human health. Until now, the only anti-TB vaccine approved for use is the live attenuated…”
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Epidemiological characteristics and trends of notifiable infectious diseases in China from 1986 to 2016 by Jiang, Yi, Dou, Xiangfeng, Yan, Chenqi, Wan, Li, Liu, Haican, Li, Machao, Wang, Ruibai, Li, Guilian, Zhao, Lili, Liu, Zhiguang, Zhao, Xiuqin, Wan, Kanglin

“…Since the 1980s, China has undergone significant social change and the incidence of infectious diseases has also changed considerably. Here, we report the…”
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High Immunogenicity of a T-Cell Epitope-Rich Recombinant Protein Rv1566c-444 From Mycobacterium tuberculosis in Immunized BALB/c Mice, Despite Its Low Diagnostic Sensitivity by Luan, Xiuli, Fan, Xueting, Wang, Ruihuan, Deng, Yunli, Chen, Zixin, Li, Na, Yan, Yuhan, Li, Xiaoyan, Liu, Haican, Li, Guilian, Wan, Kanglin

“…The discovery of immunodominant antigens is of great significance for the development of new especially sensitive diagnostic reagents and effective vaccines in…”
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Spoligotypes of Mycobacterium tuberculosis from Different Provinces of China by Dong, Haiyan, Liu, Zhiguang, Lv, Bing, Zhang, Yuanyuan, Liu, Jie, Zhao, Xiuqin, Liu, Jinghua, Wan, Kanglin

“…A total of 2,346 Mycobacterium tuberculosis isolates from 13 provinces in China were genotyped by spoligotyping. Two hundred seventy-eight spoligotypes were…”
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Study of efflux pump gene expression in rifampicin-monoresistant Mycobacterium tuberculosis clinical isolates by Li, Guilian, Zhang, Jingrui, Guo, Qian, Wei, Jianhao, Jiang, Yi, Zhao, Xiuqin, Zhao, Li-li, Liu, Zhiguang, Lu, Jianxin, Wan, Kanglin

“…Rifampicin (RIF) resistance is a risk factor for poor outcome in tuberculosis (TB). In Mycobacterium tuberculosis , both target gene mutation and efflux pumps…”
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Genetic diversity of Mycobacterium tuberculosis isolates from Tibetans in Tibet, China by Dong, Haiyan, Shi, Li, Zhao, Xiuqin, Sang, Ba, Lv, Bing, Liu, Zhiguang, Wan, Kanglin

“…Tuberculosis (TB) is a serious health problem in Tibet where Tibetans are the major ethnic group. Although genotyping of Mycobacterium tuberculosis (M…”
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