Search Results - "Wan, Huan Ying"
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Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial
Published in The lancet respiratory medicine (01-03-2014)“…Summary Background Increased oxidative stress and inflammation has a role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Drugs with…”
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Angiotensin-(1-7) decreases the expression of collagen I via TGF-β1/Smad2/3 and subsequently inhibits fibroblast-myofibroblast transition
Published in Clinical science (1979) (01-11-2016)“…Previous studies have shown that the RAS (renin-angiotensin system) might participate in airway remodelling in asthma. As a main component of the RAS,…”
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Coexistence of Th1/Th2 and Th17/Treg imbalances in patients with allergic asthma
Published in Chinese medical journal (05-07-2011)“…Recent recognition is that Th2 response is insufficient to fully explain the aetiology of asthma. Other CD4(+) T cells subsets might play a role in asthma. We…”
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Obstructive sleep apnea is associated with impaired glucose metabolism in Han Chinese subjects
Published in Chinese medical journal (01-01-2013)“…Background Increasingly, evidence from population, clinic-based and laboratory studies supports an independent association between obstructive sleep apnea…”
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5
An increased ratio of Th2/Treg cells in patients with moderate to severe asthma
Published in Chinese medical journal (20-06-2013)“…Background Recent studies have shown that T helper type-2 (Th2) cells can induce the apoptosis of CD4+CD25+ Treg cells or resist the immunosuppressive effect…”
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Chronic Intermittent Hypoxia Induces Thioredoxin System Changes in a Gender-Specific Fashion in Mice
Published in The American journal of the medical sciences (01-06-2012)“…Abstract Obstructive sleep apnea (OSA) is an independent risk factor of multisystem injury including liver and cardiovascular system. Chronic intermittent…”
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Association between the interleukin-13 gene and development of chronic obstructive pulmonary disease in southern Chinese Han population: a case-control study
Published in Chinese medical journal (05-12-2013)“…Background Interleukin-13 (IL-13) has been implicated to be responsible for recruitment of inflammatory cells from the blood to the lung,regulation of matrix…”
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Preliminary molecular epidemiology of the Staphylococcus aureus in lower respiratory tract infections: a multicenter study in China
Published in Chinese medical journal (01-03-2011)“…Background Staphylococcus aureus (S. aureus) remains as an important microbial pathogen resulting in community and nosocomial acquired infections with…”
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Drug-resistant genes carried by Acinetobacter baumanii isolated from patients with lower respiratory tract infection
Published in Chinese medical journal (20-09-2010)“…Background Acinetobacter baumanii (A. baumanii ) remains an important microbial pathogen resulting in nosocomialacquired infections with significant morbidity…”
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10
Validity of Asthma Control Test in Chinese patients
Published in Chinese medical journal (20-06-2007)“…So far, in China, there has been no effective or easy procedure to define the control of asthma. This study assesses the validity of Asthma Control Test in…”
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Effects of thrombolytic drugs and a selective endothelin-1 receptor antagonist on acute pulmonary thromboembolism in dogs
Published in Chinese medical journal (20-02-2010)“…Background It has been shown that neurohumoral factors other than mechanical obstruction are involved in the pathophysiology of acute pulmonary thromboembolism…”
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12
Angiotensin-converting enzyme 2 attenuates the metastasis of non-small cell lung cancer through inhibition of epithelial-mesenchymal transition
Published in Oncology reports (01-06-2013)“…Angiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin-angiotensin system (RAS). ACE2 plays a critical counterbalancing role by degrading…”
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Gemcitabine and cisplatin treatment over a 3-week versus a 4-week dosing schedule: a randomized trial coducted in Chinese patients with nonsmall cell lung cancer
Published in Chinese medical journal (20-05-2008)“…Background Gemcitabine plus cisplatin is a standard treatment for stages IIIB and IV nonsmall cell lung cancer (NSCLC). This randomized phase Ⅱ study evaluated…”
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Effect of smoking cessation on airway inflammation of rats with chronic bronchitis
Published in Chinese medical journal (05-09-2007)“…Smoking is the major cause of airway inflammation in chronic obstructive pulmonary disease (COPD), and smoking cessation is regarded as one of the important…”
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Levels of thioredoxin are related to the severity of obstructive sleep apnea: based on oxidative stress concept
Published in Sleep & breathing (01-03-2013)“…Background Oxidative stress is a typical feature of obstructive sleep apnea (OSA). Thioredoxin (TRX), as one of the oxidative stress biomarkers, is a potent…”
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Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers
Published in International journal of oncology (01-09-2013)“…Squamous cell lung cancer is a major histotype of non-small cell lung cancer (NSCLC) that is distinct from lung adenocarcinoma. We used whole-exome sequencing…”
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MUC5AC expression up-regulation goblet cell hyperplasia in the airway of patients with chronic obstructive pulmonary disease
Published in Chinese medical sciences journal (01-09-2005)“…To determine the number of goblet cells, the change of MUC5AC expression in chronic obstructive pulmonary disease (COPD) patients and the relationship of…”
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Pulmonary Function Parameters in High-resolution Computed Tomography Phenotypes of Chronic Obstructive Pulmonary Disease
Published in The American journal of the medical sciences (01-03-2015)“…Abstract Background Heterogeneity of clinical presentation of chronic obstructive pulmonary disease (COPD) attributes to different pathological basis…”
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Quantification of Circulating Cell-Free DNA in the Serum of Patients with Obstructive Sleep Apnea-Hypopnea Syndrome
Published in Lung (01-12-2010)“…Serum cell-free DNA concentrations have been reported to increase in many acute diseases as well as in some chronic conditions such as cancer and autoimmune…”
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CD39/CD73 and the imbalance of Th17 cells and regulatory T cells in allergic asthma
Published in Molecular medicine reports (01-11-2013)“…In the immune system, CD4+CD25+Foxp3+ regulatory T cells (Tregs) maintain self-tolerance and Th17 cells mediate inflammatory responses. CD39 is expressed on…”
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