Search Results - "Wan, Guoyun"

Stepwise pH-responsive nanoparticles containing charge-reversible pullulan-based shells and poly(β-amino ester)/poly(lactic-co-glycolic acid) cores as carriers of anticancer drugs for combination therapy on hepatocellular carcinoma by Zhang, Cong, An, Tong, Wang, Dan, Wan, Guoyun, Zhang, Mingming, Wang, Hemei, Zhang, Sipei, Li, Rongshan, Yang, Xiaoying, Wang, Yinsong

“…Stepwise pH-responsive nanoparticle system containing charge reversible pullulan-based (CAPL) shell and poly(β-amino ester) (PBAE)/poly(lactic-co-glycolic…”
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Leukocyte/platelet hybrid membrane-camouflaged dendritic large pore mesoporous silica nanoparticles co-loaded with photo/chemotherapeutic agents for triple negative breast cancer combination treatment by Zhang, Tao, Liu, Hui, Li, Ling, Guo, Zhaoyang, Song, Jia, Yang, Xiaoying, Wan, Guoyun, Li, Rongshan, Wang, Yinsong

“…Triple-negative breast cancer (TNBC) is an aggressive subset of breast cancer and currently lacks effective therapeutic targets. As two main phototherapeutic…”
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pH and redox dual-responsive nanoparticles based on disulfide-containing poly(β-amino ester) for combining chemotherapy and COX-2 inhibitor to overcome drug resistance in breast cancer by Zhang, Sipei, Guo, Nan, Wan, Guoyun, Zhang, Tao, Li, Chunyu, Wang, Yongfei, Wang, Yinsong, Liu, Yuanyuan

“…Multidrug resistance (MDR) generally leads to breast cancer treatment failure. The most common mechanism of MDR is the overexpression of ATP-binding cassette…”
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Gene augmented nuclear-targeting sonodynamic therapy via Nrf2 pathway-based redox balance adjustment boosts peptide-based anti-PD-L1 therapy on colorectal cancer by Wan, Guoyun, Chen, Xuheng, Wang, Haijiao, Hou, Shenglei, Wang, Qian, Cheng, Yuanyuan, Chen, Qian, Lv, Yingge, Chen, Hongli, Zhang, Qiqing

“…Colorectal cancer is known to be resistant to immune checkpoint blockade (ICB) therapy. Sonodynamic therapy (SDT) has been reported to improve the efficacy of…”
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A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma by Liu, Yang, Wan, Guoyun, Guo, Hua, Liu, Yuanyuan, Zhou, Ping, Wang, Hemei, Wang, Dan, Zhang, Sipei, Wang, Yinsong, Zhang, Ning

“…Hepatocellular carcinoma （HCC） is one of the most common and deadly malignancies worldwide. To date, the survival of patients with HCC has not improved because…”
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Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases by Wang, Bin, Chen, Xuheng, Chen, Zhiyuan, Xiao, Huiwen, Dong, Jiali, Li, Yuan, Zeng, Xiaozhou, Liu, Jinjian, Wan, Guoyun, Fan, Saijun, Cui, Ming

“…Gut microbial preparations are widely used in treating intestinal diseases but show mixed success. In this study, we found that the therapeutic efficacy of A…”
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Dual pH-responsive multifunctional nanoparticles for targeted treatment of breast cancer by combining immunotherapy and chemotherapy by Liu, Yuanyuan, Qiao, Linan, Zhang, Sipei, Wan, Guoyun, Chen, Bowei, Zhou, Ping, Zhang, Ning, Wang, Yinsong

“…[Display omitted] In the present study, a dual pH-responsive multifunctional nanoparticle system was designed for combining immunotherapy and chemotherapy to…”
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An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling by Cheng, Yuanyuan, Chen, Qian, Guo, Zhaoyang, Li, Mengwen, Yang, Xiaoying, Wan, Guoyun, Chen, Hongli, Zhang, Qiqing, Wang, Yinsong

“…Metastasis is one of the main causes of failure in the treatment of triple-negative breast cancer (TNBC). Immunotherapy brings hope and opportunity to solve…”
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Nanoscaled red blood cells facilitate breast cancer treatment by combining photothermal/photodynamic therapy and chemotherapy by Wan, Guoyun, Chen, Bowei, Li, Ling, Wang, Dan, Shi, Shurui, Zhang, Tao, Wang, Yue, Zhang, Lianyun, Wang, Yinsong

“…Red blood cells (RBCs)-based vesicles have been widely used for drug delivery due to their unique advantages. Intact RBCs contain a large amount of…”
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Nucleus-targeting near-infrared nanoparticles based on TAT peptide-conjugated IR780 for photo-chemotherapy of breast cancer by Wan, Guoyun, Cheng, Yuanyuan, Song, Jia, Chen, Qian, Chen, Bowei, Liu, Yuanyuan, Ji, Shenglu, Chen, Hongli, Wang, Yinsong

“…[Display omitted] •TAT peptide-conjugated IR780 (TAT-IR780) was synthesized.•TAT-IR780 and doxorubicin (DOX) self-assembled to form TID nanoparticles.•TID…”
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Multifunctional nanoparticles based on a polymeric copper chelator for combination treatment of metastatic breast cancer by Zhou, Ping, Qin, Jiaqi, Zhou, Ce, Wan, Guoyun, Liu, Yuanyuan, Zhang, Mingming, Yang, Xiaoying, Zhang, Ning, Wang, Yinsong

“…Copper plays an important role in tumor growth and metastasis. Copper chelation has been confirmed to be an effective strategy for breast cancer therapy…”
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Reactive Oxygen Species-Responsive Nanoparticles Based on PEGlated Prodrug for Targeted Treatment of Oral Tongue Squamous Cell Carcinoma by Combining Photodynamic Therapy and Chemotherapy by Shi, Shurui, Zhang, Lianyun, Zhu, Mengqi, Wan, Guoyun, Li, Changyi, Zhang, Juan, Wang, Yue, Wang, Yinsong

“…In this study, a reactive oxygen species (ROS)-responsive nanoparticle system was designed for combining photodynamic therapy (PDT) and chemotherapy for oral…”
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Homologous-targeting biomimetic nanoparticles for photothermal therapy and Nrf2-siRNA amplified photodynamic therapy against oral tongue squamous cell carcinoma by Shi, Shurui, Wang, Yue, Wang, Beibei, Chen, Qian, Wan, Guoyun, Yang, Xiaoying, Zhang, Juan, Zhang, Lianyun, Li, Changyi, Wang, Yinsong

“…•Biomimetic M@PPI-siRNA nanoparticles were prepared for co-loading ICG and Nrf2-siRNA.•M@PPI-siRNA nanoparticles exhibited homologous OTSCC-targeting…”
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A pH-sensitive nanotherapeutic system based on a marine sulfated polysaccharide for the treatment of metastatic breast cancer through combining chemotherapy and COX-2 inhibition by Zhang, Tao, Liu, Hui, Li, Yating, Li, Chunyu, Wan, Guoyun, Chen, Bowei, Li, Chunxia, Wang, Yinsong

“…[Display omitted] Metastasis and chemotherapy resistance are the leading causes of breast cancer mortality. Celecoxib (CXB), a selective cyclooxygenase-2…”
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Catalase-positive Staphylococcus epidermidis based cryo-millineedle platform facilitates the photo-immunotherapy against colorectal cancer via hypoxia improvement by Wang, Haijiao, Gou, Ruiling, Chen, Jiayu, Wang, Qian, Li, Xiaoyu, Chang, Jiaxin, Chen, Hongli, Wang, Xianwen, Wan, Guoyun

“…[Display omitted] •A novel catalase-positive Staphylococcus epidermidis based cryo-millineedle platform was successfully prepared.•The cryo-millineedle…”
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Design of Dendritic Large-Pore Mesoporous Silica Nanoparticles with Controlled Structure and Formation Mechanism in Dual-Templating Strategy by Guo, Zhaoyang, Wu, Liting, Wang, Yang, Zhu, Yanpeng, Wan, Guoyun, Li, Rongshan, Zhang, Yinghua, Qian, Dong, Wang, Yinsong, Zhou, Xiang, Liu, Zunfeng, Yang, Xiaoying

“…Dendritic large-pore mesoporous silica nanoparticles (DLMSN) is an important biodegradable drug carrier due to its high porosity, which can be prepared by…”
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Biomimetic nanotherapeutics based on oxygen supply and ultrasmall Cu-Se-Au alloy nanoparticles for boosting radio-photothermal ablation of breast cancer by Guo, Zhaoyang, Xin, Yujia, Yang, Lan, Ran, Ruixue, Wan, Guoyun, Ma, Aijing, Ren, Hongying, Wang, Yinsong, Yang, Xiaoying

“…Radiotherapy (RT) is one of the important tools for clinical treatment of breast cancer. Currently, some nanoradiosensitizers have been developed for…”
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Corrigendum to “Multifunctional nanoparticles based on a polymeric copper chelator for combination treatment of metastatic breast cancer” [Biomaterials 195 (2019) 86–99] by Zhou, Ping, Qin, Jiaqi, Zhou, Ce, Wan, Guoyun, Liu, Yuanyuan, Zhang, Mingming, Yang, Xiaoying, Zhang, Ning, Wang, Yinsong

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PEGylated doxorubicin nanoparticles mediated by HN-1 peptide for targeted treatment of oral squamous cell carcinoma by Wang, Yue, Wan, Guoyun, Li, Zhiyuan, Shi, Shurui, Chen, Bowei, Li, Chunyu, Zhang, Lianyun, Wang, Yinsong

“…[Display omitted] HN-1, a 12-amino acid peptide, has been reported to possess strong capabilities for targeting and penetrating head and neck squamous cell…”
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A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma by Wang, Yan, Liu, Yuanyuan, Liu, Yang, Zhou, Wen, Wang, Hemei, Wan, Guoyun, Sun, Duxin, Zhang, Ning, Wang, Yinsong

“…[Display omitted] A polymeric prodrug of cisplatin (CP) with simple chemical structure was synthesized based on pullulan and its therapeutic effects on human…”
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