Search Results - "Wamiru, Antony"

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana by Jiang, Wei, Wang, Dongdong, Wilson, Brice A P, Kang, Unwoo, Bokesch, Heidi R, Smith, Emily A, Wamiru, Antony, Goncharova, Ekaterina I, Voeller, Donna, Lipkowitz, Stanley, O'Keefe, Barry R, Gustafson, Kirk R

“…An extract of the coralline demosponge inhibited the ubiquitin ligase activity of the immunomodulatory protein Cbl-b. The bioassay-guided separation of the…”
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Madurahydroxylactone Derivatives as Dual Inhibitors of Human Immunodeficiency Virus Type 1 Integrase and RNase H by MARCHAND, Christophe, BEUTLER, John A, WAMIRU, Antony, BUDIHAS, Scott, MÖLLMANN, Ute, HEINISCH, Lothar, MELLORS, John W, LE GRICE, Stuart F, POMMIER, Yves

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Photochemical Dimerization of Plakinidine B Leads to Potent Inhibition of the E3 Ubiquitin-Protein Ligase CBL‑B by Khong, Quan T., Li, Donghao, Wilson, Brice A. P., Ranguelova, Kalina, Dalilian, Masoumeh, Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Grkovic, Tanja, Voeller, Donna, Lipkowitz, Stanley, Schnermann, Martin J., O’Keefe, Barry R., Du, Lin

“…A new dimeric alkaloid plakoramine A [(±)-1] was identified from a marine sponge Plakortis sp. Chiral-phase HPLC separation of (±)-1 led to the purified…”
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Acroamine A, a 2‑Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha by Senadeera, Sarath P. D., Wang, Dongdong, Wilson, Brice A. P., Smith, Emily A., Wamiru, Antony, Martinez Fiesco, Juliana A., Du, Lin, Zhang, Ping, O’Keefe, Barry R., Beutler, John A.

“…A high throughput screen performed to identify catalytic inhibitors of the oncogenic fusion form of cAMP-dependent protein kinase A catalytic subunit alpha…”
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Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases by Du, Lin, Wilson, Brice A. P., Li, Ning, Shah, Rohan, Dalilian, Masoumeh, Wang, Dongdong, Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Zhang, Ping, O’Keefe, Barry R.

“…The DNAJB1–PRKACA oncogenic gene fusion results in an active kinase enzyme, J-PKAcα, that has been identified as an attractive antitumor target for…”
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Harnessing Natural Product Diversity for Fluorophore Discovery: Naturally Occurring Fluorescent Hydroxyanthraquinones from the Marine Crinoid Pterometra venusta by Singh, A. Jonathan, Gorka, Alexander P, Bokesch, Heidi R, Wamiru, Antony, O’Keefe, Barry R, Schnermann, Martin J, Gustafson, Kirk R

“…Fluorescent small molecules are important tools in many aspects of modern biology. A two-stage evaluation process involving fluorescence screening and…”
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Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′,5′-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors by Wilson, Brice A. P., Li, Ning, Martinez Fiesco, Juliana A., Dalilian, Masoumeh, Wang, Dongdong, Smith, Emily A., Wamiru, Antony, Shah, Rohan, Goncharova, Ekaterina I., Beutler, John A., Grkovic, Tanja, Zhang, Ping, O’Keefe, Barry R.

“…The recent demonstration that adenosine 3′,5′-cyclic monophosphate (cAMP)-dependent protein kinase A (PKA) plays an oncogenic role in a number of important…”
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Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones by Budihas, Scott R., Gorshkova, Inna, Gaidamakov, Sergei, Wamiru, Antony, Bona, Marion K., Parniak, Michael A., Crouch, Robert J., McMahon, James B., Beutler, John A., Le Grice, Stuart F. J.

“…High-throughput screening of a National Cancer Institute library of pure natural products identified the hydroxylated tropolone derivatives β-thujaplicinol…”
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In Vitro Ubiquitination Platform Identifies Methyl Ellipticiniums as Ubiquitin Ligase Inhibitors by Wilson, Brice A P, Voeller, Donna, Smith, Emily A, Wamiru, Antony, Goncharova, Ekaterina I, Liu, Gang, Lipkowitz, Stanley, O'Keefe, Barry R

“…The transfer of the small protein ubiquitin to a target protein is an intricately orchestrated process called ubiquitination that results in modulation of…”
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Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro by Dull, Angie B, George, Anuja A, Goncharova, Ekaterina I, Evans, Jason R, Wamiru, Antony, Cartner, Laura K, Hager, Gordon L, McMahon, James B

“…We have completed a robust high-content imaging screen for novel estrogen receptor α (ERα) agonists and antagonists by quantitation of cytoplasmic to nuclear…”
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HIV-1 Ribonuclease H Inhibitory Phenolic Glycosides from Eugenia hyemalis by Bokesch, Heidi R, Wamiru, Antony, Le Grice, Stuart F. J, Beutler, John A, McKee, Tawnya C, McMahon, James B

“…Three new galloyl arbutins, hyemalosides A−C (1−3), along with nine known compounds were isolated from the evergreen tree Eugenia hyemalis. The structures of…”
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A Dimeric Lactone from Ardisia japonica with Inhibitory Activity for HIV-1 and HIV-2 Ribonuclease H by Dat, Nguyen Tien, Bae, KiHwan, Wamiru, Antony, McMahon, James B, Le Grice, Stuart F. J, Bona, Marion, Beutler, John A, Kim, Young Ho

“…A new dimeric lactone, ardimerin digallate (1), was isolated from the whole plants of Ardisia japonica, along with six known constituents. The structure of 1…”
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An HIV RNase H Inhibitory 1,3,4,5-Tetragalloylapiitol from the African Plant Hylodendron gabunensis by Takada, Kentaro, Bermingham, Alun, O’Keefe, Barry R, Wamiru, Antony, Beutler, John A, Le Grice, Stuart F. J, Lloyd, John, Gustafson, Kirk R, McMahon, James B

“…A new compound, 1,3,4,5-tetragalloylapiitol (1), was isolated from the aqueous extract of the plant Hylodendron gabunensis and was found to be a potent…”
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A capillary electrophoretic assay for ribonuclease H activity by Chan, King C, Budihas, Scott R, Le Grice, Stuart F.J, Parniak, Michael A, Crouch, Robert J, Gaidamakov, Sergei A, Isaaq, Haleem J, Wamiru, Antony, McMahon, James B, Beutler, John A

“…A capillary electrophoretic assay was developed to measure the ribonuclease (RNase) H activity of human immunodeficiency virus (HIV) type 1 reverse…”
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