Search Results - "Walum, Joshua"

Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle by Jackson, Devine, Walum, Joshua, Banerjee, Priyanka, Lewis, Brandon W, Prakash, Y S, Sathish, Venkatachalem, Xu, Zhaohui, Britt, Jr, Rodney D

“…Corticosteroids remain a key therapy for treating children with asthma. Patients with severe asthma are insensitive, resistant, or refractory to…”
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Chronic Allergen Challenge Induces Corticosteroid Insensitivity With Persistent Airway Remodeling and Type 2 Inflammation by Lewis, Brandon W, Ford, Maria L, Khan, Aiman Q, Walum, Joshua, Britt, Jr, Rodney D

“…Type 2-high severe asthma is described as a distinct endotype with Th2 inflammation, high eosinophil lung infiltration, impaired lung function, and reduced…”
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Innate immune responses are increased in children with acute asthma exacerbation by Sheikh, Shahid, Eisner, Mariah, Walum, Joshua, Heyob, Kathryn, Khan, Aiman Q., Lewis, Brandon, Grayson, Mitchell, Kopp, Benjamin, McCoy, Karen, Britt, Rodney

“…Background Little is known about the immune responses during acute asthma exacerbation. In this study, we examined immune responses in children following an…”
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PRMT5 in T cells drives Th17 responses, mixed granulocytic inflammation and severe allergic airway inflammation1 by Lewis, Brandon W., Amici, Stephanie A., Kim, Hye-Young, Shalosky, Emily M., Khan, Aiman Q., Walum, Joshua, Gowdy, Kymberly M., Englert, Joshua A., Porter, Ned A., Grayson, Mitchell H., Britt, Rodney D., Guerau-de-Arellano, Mireia

“…Severe asthma is characterized by steroid insensitivity and poor symptom control, and is responsible for the majority of asthma-related hospital costs…”
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Corticosteroid insensitivity persists in the absence of STAT1 signaling in severe allergic airway inflammation by Lewis, Brandon W, Jackson, Devine, Amici, Stephanie A, Walum, Joshua, Guessas, Manel, Guessas, Sonia, Coneglio, Elise, Boda, Akhila V, Guerau-de-Arellano, Mireia, Grayson, Mitchell H, Britt, Jr, Rodney D

“…Corticosteroid insensitivity in asthma limits the ability to effectively manage severe asthma, which is characterized by persistent airway inflammation, airway…”
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PRMT5 in T Cells Drives Th17 Responses, Mixed Granulocytic Inflammation, and Severe Allergic Airway Inflammation by Lewis, Brandon W, Amici, Stephanie A, Kim, Hye-Young, Shalosky, Emily M, Khan, Aiman Q, Walum, Joshua, Gowdy, Kymberly M, Englert, Joshua A, Porter, Ned A, Grayson, Mitchell H, Britt, Jr, Rodney D, Guerau-de-Arellano, Mireia

“…Severe asthma is characterized by steroid insensitivity and poor symptom control and is responsible for most asthma-related hospital costs. Therapeutic options…”
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