Search Results - "Waltz, James"
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The neural underpinnings of cognitive flexibility and their disruption in psychotic illness
Published in Neuroscience (14-03-2017)“…Highlights • Different subgroups of patients show deficits in set-shifting vs. set-maintenance. • There is heterogeneity in the functioning of frontostriatal…”
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Towards a Unifying Cognitive, Neurophysiological, and Computational Neuroscience Account of Schizophrenia
Published in Schizophrenia bulletin (11-09-2019)“…Psychotic experiences may be understood as altered information processing due to aberrant neural computations. A prominent example of such neural computations…”
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Probabilistic reversal learning impairments in schizophrenia: Further evidence of orbitofrontal dysfunction
Published in Schizophrenia research (01-07-2007)“…Abstract Impairments in feedback processing and reinforcement learning appear to be prominent aspects of schizophrenia (SZ), which may relate to symptoms of…”
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A Review of Reward Processing and Motivational Impairment in Schizophrenia
Published in Schizophrenia bulletin (01-03-2014)“…This article reviews and synthesizes research on reward processing in schizophrenia, which has begun to provide important insights into the cognitive and…”
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Effort Cost Computation in Schizophrenia: A Commentary on the Recent Literature
Published in Biological psychiatry (1969) (01-12-2015)“…Abstract The cognitive and affective factors implicated in the motivational impairments seen in many people with schizophrenia remain poorly understood. Many…”
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Negative Symptoms of Schizophrenia Are Associated with Abnormal Effort-Cost Computations
Published in Biological psychiatry (1969) (15-07-2013)“…Background Decision-making studies show that response selection is influenced by the “effort cost” associated with response alternatives. These effort-cost…”
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Working memory contributions to reinforcement learning impairments in schizophrenia
Published in The Journal of neuroscience (08-10-2014)“…Previous research has shown that patients with schizophrenia are impaired in reinforcement learning tasks. However, behavioral learning curves in such tasks…”
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The roles of reward, default, and executive control networks in set-shifting impairments in schizophrenia
Published in PloS one (27-02-2013)“…Patients with schizophrenia (SZ) show deficits on tasks of rapid reinforcement learning, like probabilistic reversal learning (PRL), but the neural bases for…”
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Interactions Among Working Memory, Reinforcement Learning, and Effort in Value-Based Choice: A New Paradigm and Selective Deficits in Schizophrenia
Published in Biological psychiatry (1969) (15-09-2017)“…When studying learning, researchers directly observe only the participants’ choices, which are often assumed to arise from a unitary learning process. However,…”
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Probabilistic Reversal Learning in Schizophrenia: Stability of Deficits and Potential Causal Mechanisms
Published in Schizophrenia bulletin (01-07-2016)“…Although individuals with schizophrenia show impaired feedback-driven learning on probabilistic reversal learning (PRL) tasks, the specific factors that…”
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An integrated cluster‐wise significance measure for fMRI analysis
Published in Human brain mapping (01-06-2022)“…Cluster‐wise inference is widely used in fMRI analysis. The cluster‐level statistic is often obtained by counting the number of intra‐cluster voxels which…”
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From Childhood Trauma to Delusions: It’s Complicated
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01-07-2022)Get full text
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Phenomenological and Cognitive Features Associated With Auditory Hallucinations in Clinical and Nonclinical Voice Hearers
Published in Schizophrenia bulletin (29-11-2023)“…Abstract Background and Hypotheses Auditory verbal hallucinations (AVH) are central features of schizophrenia (SZ). However, AVH also occur in a small…”
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All or nothing belief updating in patients with schizophrenia reduces precision and flexibility of beliefs
Published in Brain (London, England : 1878) (12-04-2021)“…Schizophrenia is characterized by abnormal perceptions and beliefs, but the computational mechanisms through which these abnormalities emerge remain unclear…”
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Selective Reinforcement Learning Deficits in Schizophrenia Support Predictions from Computational Models of Striatal-Cortical Dysfunction
Published in Biological psychiatry (1969) (01-10-2007)“…Background Rewards and punishments may make distinct contributions to learning via separate striatal-cortical pathways. We investigated whether fronto-striatal…”
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Extracting brain disease‐related connectome subgraphs by adaptive dense subgraph discovery
Published in Biometrics (01-12-2022)“…Group‐level brain connectome analysis has attracted increasing interest in neuropsychiatric research with the goal of identifying connectomic subnetworks…”
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Synchronized delta oscillations correlate with the resting-state functional MRI signal
Published in Proceedings of the National Academy of Sciences - PNAS (13-11-2007)“…Synchronized low-frequency spontaneous fluctuations of the functional MRI (fMRI) signal have recently been applied to investigate large-scale neuronal networks…”
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Increased Sensitivity to Effort and Perception of Effort in People with Schizophrenia
Published in Schizophrenia bulletin (21-09-2024)“…Motivational deficits in schizophrenia are proposed to be attributable in part to abnormal effort-cost computations, calculations weighing the costs vs. the…”
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Cognitive effort avoidance and detection in people with schizophrenia
Published in Cognitive, affective, & behavioral neuroscience (01-03-2015)“…Many people with schizophrenia exhibit avolition, a difficulty initiating and maintaining goal-directed behavior, considered to be a key negative symptom of…”
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Motivational Deficits in Schizophrenia and the Representation of Expected Value
Published in Current topics in behavioral neurosciences (01-01-2016)“…Motivational deficits (avolition and anhedonia) have historically been considered important negative symptoms of schizophrenia (SZ). Numerous studies have…”
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