Search Results - "Walton, Paul"

On the catalytic mechanisms of lytic polysaccharide monooxygenases by Walton, Paul H, Davies, Gideon J

“…•Lytic polysaccharide monooxygenases are newly discovered copper oxygenases.•LPMOs open up new thinking about oxidation mechanisms.•Copper histidine brace…”
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The Peroxisome-Mitochondria Connection: How and Why? by Fransen, Marc, Lismont, Celien, Walton, Paul

“…Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid and reactive oxygen species metabolism. In mammals, these…”
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Molecular Mechanisms of Oxygen Activation and Hydrogen Peroxide Formation in Lytic Polysaccharide Monooxygenases by Wang, Binju, Walton, Paul H, Rovira, Carme

“…Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes for the degradation of recalcitrant polysaccharides such as chitin and cellulose…”
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Secreted pectin monooxygenases drive plant infection by pathogenic oomycetes by Sabbadin, Federico, Urresti, Saioa, Henrissat, Bernard, Avrova, Anna O., Welsh, Lydia R. J., Lindley, Peter J., Csukai, Michael, Squires, Julie N., Walton, Paul H., Davies, Gideon J., Bruce, Neil C., Whisson, Stephen C., McQueen-Mason, Simon J.

“…Potato pectin falls to Phytophthora Phytophthora infestans is a plant oomycete pathogen that drove the potato famines of the 1800s and continues to afflict…”
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Lytic xylan oxidases from wood-decay fungi unlock biomass degradation by Couturier, Marie, Ladevèze, Simon, Sulzenbacher, Gerlind, Ciano, Luisa, Fanuel, Mathieu, Moreau, Céline, Villares, Ana, Cathala, Bernard, Chaspoul, Florence, Frandsen, Kristian E, Labourel, Aurore, Herpoël-Gimbert, Isabelle, Grisel, Sacha, Haon, Mireille, Lenfant, Nicolas, Rogniaux, Hélène, Ropartz, David, Davies, Gideon J, Rosso, Marie-Noëlle, Walton, Paul H, Henrissat, Bernard, Berrin, Jean-Guy

“…A new type of fungal lytic polysaccharide monooxygenase (LPMO) catalyzes the oxidative degradation of xylan components of cellulosic biomass and offers…”
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Author Correction: Enzymes knuckle down to the job by Walton, Paul H.

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An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion by Sabbadin, Federico, Hemsworth, Glyn R., Ciano, Luisa, Henrissat, Bernard, Dupree, Paul, Tryfona, Theodora, Marques, Rita D. S., Sweeney, Sean T., Besser, Katrin, Elias, Luisa, Pesante, Giovanna, Li, Yi, Dowle, Adam A., Bates, Rachel, Gomez, Leonardo D., Simister, Rachael, Davies, Gideon J., Walton, Paul H., Bruce, Neil C., McQueen-Mason, Simon J.

“…Thermobia domestica belongs to an ancient group of insects and has a remarkable ability to digest crystalline cellulose without microbial assistance. By…”
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Enzymes knuckle down to the job by Walton, Paul H.

“…A suite of new enzymes reveals more on how Nature breaks down plant-based polysaccharides and how these enzymes might be harnessed in the utilization of…”
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Discovery and characterization of a new family of lytic polysaccharide monooxygenases by Hemsworth, Glyn R, Henrissat, Bernard, Davies, Gideon J, Walton, Paul H

“…Use of a domain of unknown function as the input for bioinformatic searching reveals a new Cu-dependent family of chitinases, assigned as CAZy group AA11, that…”
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Lytic Polysaccharide Monooxygenases in Biomass Conversion by Hemsworth, Glyn R, Johnston, Esther M, Davies, Gideon J, Walton, Paul H

“…The derivation of second-generation biofuels from non-edible biomass is viewed as crucial for establishing a sustainable bio-based economy for the future. The…”
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The Limitations of Decision-Making by Walton, Paul

“…In a world faced with technological, health and environmental change and uncertainty, decision-making is challenging. In addition, decision-making itself is…”
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Artificial Intelligence and the Limitations of Information by Walton, Paul

“…Artificial intelligence (AI) and machine learning promise to make major changes to the relationship of people and organizations with technology and…”
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Activation of O2 and H2O2 by Lytic Polysaccharide Monooxygenases by Wang, Binju, Wang, Zhanfeng, Davies, Gideon J, Walton, Paul H, Rovira, Carme

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The peroxisomal import receptor PEX5 functions as a stress sensor, retaining catalase in the cytosol in times of oxidative stress by Walton, Paul A., Brees, Chantal, Lismont, Celien, Apanasets, Oksana, Fransen, Marc

“…Accumulating evidence indicates that peroxisome functioning, catalase localization, and cellular oxidative balance are intimately interconnected. Nevertheless,…”
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Recent insights into copper-containing lytic polysaccharide mono-oxygenases by Hemsworth, Glyn R, Davies, Gideon J, Walton, Paul H

“…•Recently discovered polysaccharide mono-oxygenases are copper-containing enzymes.•Different sequence families in bacteria and fungi are structurally similar…”
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QM/MM Studies into the H2O2‑Dependent Activity of Lytic Polysaccharide Monooxygenases: Evidence for the Formation of a Caged Hydroxyl Radical Intermediate by Wang, Binju, Johnston, Esther M, Li, Pengfei, Shaik, Sason, Davies, Gideon J, Walton, Paul H, Rovira, Carme

“…Lytic polysaccharide monooxygenases (LPMOs) are promising enzymes for the conversion of lignocellulosic biomass into biofuels and biomaterials. Classically…”
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Formation of a Copper(II)–Tyrosyl Complex at the Active Site of Lytic Polysaccharide Monooxygenases Following Oxidation by H2O2 by Paradisi, Alessandro, Johnston, Esther M, Tovborg, Morten, Nicoll, Callum R, Ciano, Luisa, Dowle, Adam, McMaster, Jonathan, Hancock, Y, Davies, Gideon J, Walton, Paul H

“…Hydrogen peroxide is a cosubstrate for the oxidative cleavage of saccharidic substrates by copper-containing lytic polysaccharide monooxygenases (LPMOs). The…”
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The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases by Frandsen, Kristian E H, Simmons, Thomas J, Dupree, Paul, Poulsen, Jens-Christian N, Hemsworth, Glyn R, Ciano, Luisa, Johnston, Esther M, Tovborg, Morten, Johansen, Katja S, von Freiesleben, Pernille, Marmuse, Laurence, Fort, Sébastien, Cottaz, Sylvain, Driguez, Hugues, Henrissat, Bernard, Lenfant, Nicolas, Tuna, Floriana, Baldansuren, Amgalanbaatar, Davies, Gideon J, Lo Leggio, Leila, Walton, Paul H

“…Lytic polysaccharide monooxygenases (LPMOs) are a class of copper-dependent enzymes that oxidatively degrade polysaccharides and find use in industrial…”
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The Contribution of Non-catalytic Carbohydrate Binding Modules to the Activity of Lytic Polysaccharide Monooxygenases by Crouch, Lucy I., Labourel, Aurore, Walton, Paul H., Davies, Gideon J., Gilbert, Harry J.

“…Lignocellulosic biomass is a sustainable industrial substrate. Copper-dependent lytic polysaccharide monooxygenases (LPMOs) contribute to the degradation of…”
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Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5‑Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing by Mathieu, Yann, Offen, Wendy A, Forget, Stephanie M, Ciano, Luisa, Viborg, Alexander Holm, Blagova, Elena, Henrissat, Bernard, Walton, Paul H, Davies, Gideon J, Brumer, Harry

“…Alternatives to petroleum-based chemicals are highly sought-after for ongoing efforts to reduce the damaging effects of human activity on the environment…”
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