Search Results - "Walton, Jeffrey G. A."

Peptides for cell-selective drug delivery by Svensen, Nina, Walton, Jeffrey G.A, Bradley, Mark

“…The ability to target specific cell types to achieve optimal distribution of therapeutic entities into diseased tissues, while limiting possible adverse…”
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Photoluminescent Carbon Dots from 1,4-Addition Polymers by Jiang, Zhiqiang, Nolan, Andrew, Walton, Jeffrey G. A., Lilienkampf, Annamaria, Zhang, Rong, Bradley, Mark

“…Photoluminescent carbon dots were synthesised directly by thermopyrolysis of 1,4‐addition polymers, allowing precise control of their properties. The effect of…”
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Click Chemistry Generated Model DNA–Peptide Heteroconjugates as Tools for Mass Spectrometry by Flett, Fiona J., Walton, Jeffrey G. A., Mackay, C. Logan, Interthal, Heidrun

“…UV cross-linking of nucleic acids to proteins in combination with mass spectrometry is a powerful technique to identify proteins, peptides, and the amino acids…”
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Optimisation of Conoidin A, a Peroxiredoxin Inhibitor by Liu, Gu, Botting, Catherine H., Evans, Kathryn M., Walton, Jeffrey A. G., Xu, Guogang, Slawin, Alexandra M. Z., Westwood, Nicholas J.

“…Lead optimisation: Interest in the inhibition of peroxiredoxin has been revitalised by their recently identified role in signalling cascades. Here, the…”
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Fluorescent Formazans and Tetrazolium Salts - Towards Fluorescent Cytotoxicity Assays by Ladyman, Melissa K, Walton, Jeffrey G A, Lilienkampf, Annamaria, Bradley, Mark

“…Formazan-based colorimetric cytotoxicity assays, such as the MTT assay, are typically used to assess cell viability with only metabolically active cells…”
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Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase by Walton, Jeffrey G. A., Jones, Deuan C., Kiuru, Paula, Durie, Alastair J., Westwood, Nicholas J., Fairlamb, Alan H.

“…The search for novel compounds of relevance to the treatment of diseases caused by trypanosomatid protozoan parasites continues. Screening of a large library…”
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A fluorescein-derived anthocyanidin-inspired pH sensor by Unciti-Broceta, Asier, Rahimi Yusop, M., Richardson, Patricia R., Walton, Jeffrey G.A., Bradley, Mark

“…Anthofluorescein, a new multicolor fluorophore with high pH-sensitivity in the physiological range has been synthesized from fluorescein using…”
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Cover Picture: Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase / Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 / Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase (ChemMedChem 2/2011) by Walton, Jeffrey G. A., Jones, Deuan C., Kiuru, Paula, Durie, Alastair J., Westwood, Nicholas J., Fairlamb, Alan H., Spinks, Daniel, Ong, Han B., Mpamhanga, Chidochangu P., Shanks, Emma J., Robinson, David A., Collie, Iain T., Read, Kevin D., Frearson, Julie A., Wyatt, Paul G., Brenk, Ruth, Fairlamb, Alan H., Gilbert, Ian H., Ruda, Gian Filippo, Nguyen, Corinne, Ziemkowski, Przemysław, Felczak, Krzysztof, Kasinathan, Ganasan, Musso-Buendia, Alexander, Sund, Christian, Zhou, Xiao Xiong, Kaiser, Marcel, Ruiz-Pérez, Luis M., Brun, Reto, Kulikowski, Tadeusz, Johansson, Nils Gunnar, González-Pacanowska, Dolores, Gilbert, Ian H.

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