Search Results - "Waltner, Olivia G"

TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice by Minnie, Simone A, Waltner, Olivia G, Ensbey, Kathleen S, Olver, Stuart D, Collinge, Alika D, Sester, David P, Schmidt, Christine R, Legg, Samuel Rw, Takahashi, Shuichiro, Nemychenkov, Nicole S, Sekiguchi, Tomoko, Driessens, Gregory, Zhang, Ping, Koyama, Motoko, Spencer, Andrew, Holmberg, Leona A, Furlan, Scott N, Varelias, Antiopi, Hill, Geoffrey R

“…Autologous stem cell transplantation (ASCT) with subsequent lenalidomide maintenance is standard consolidation therapy for multiple myeloma, and a subset of…”
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Cancer-Associated Fibroblast-Like Tumor Cells Remodel the Ewing Sarcoma Tumor Microenvironment by Wrenn, Emma D, Apfelbaum, April A, Rudzinski, Erin R, Deng, Xuemei, Jiang, Wei, Sud, Sudha, Van Noord, Raelene A, Newman, Erika A, Garcia, Nicolas M, Miyaki, Aya, Hoglund, Virginia J, Bhise, Shruti S, Kanaan, Sami B, Waltner, Olivia G, Furlan, Scott N, Lawlor, Elizabeth R

“…Despite limited genetic and histologic heterogeneity, Ewing sarcoma (EwS) tumor cells are transcriptionally heterogeneous and display varying degrees of…”
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Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation by Yeh, Albert C, Koyama, Motoko, Waltner, Olivia G, Minnie, Simone A, Boiko, Julie R, Shabaneh, Tamer B, Takahashi, Shuichiro, Zhang, Ping, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel R W, Sekiguchi, Tomoko, Nelson, Ethan, Bhise, Shruti S, Stevens, Andrew R, Goodpaster, Tracy, Chakka, Saranya, Furlan, Scott N, Markey, Kate A, Bleakley, Marie E, Elson, Charles O, Bradley, Philip H, Hill, Geoffrey R

“…Allogeneic T cell expansion is the primary determinant of graft-versus-host disease (GVHD), and current dogma dictates that this is driven by…”
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Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD by Wang, Yewei, Ullah, Md Ashik, Waltner, Olivia G, Bhise, Shruti S, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel Rw, Sekiguchi, Tomoko, Nelson, Ethan L, Kuns, Rachel D, Nemychenkov, Nicole S, Atilla, Erden, Yeh, Albert C, Takahashi, Shuichiro, Boiko, Julie R, Varelias, Antiopi, Blazar, Bruce R, Koyama, Motoko, Minnie, Simone A, Clouston, Andrew D, Furlan, Scott N, Zhang, Ping, Hill, Geoffrey R

“…Calcineurin inhibitors (CNIs) constitute the backbone of modern acute graft-versus-host disease (aGVHD) prophylaxis regimens but have limited efficacy in the…”
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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks by Jaeger-Ruckstuhl, Carla A, Lo, Yun, Fulton, Elena, Waltner, Olivia G, Shabaneh, Tamer B, Simon, Sylvain, Muthuraman, Pranav V, Correnti, Colin E, Newsom, Oliver J, Engstrom, Ian A, Kanaan, Sami B, Bhise, Shruti S, Peralta, Jobelle M C, Ruff, Raymond, Price, Jason P, Stull, Sylvia M, Stevens, Andrew R, Bugos, Grace, Kluesner, Mitchell G, Voillet, Valentin, Muhunthan, Vishaka, Morrish, Fionnuala, Olson, James M, Gottardo, Raphaël, Sarthy, Jay F, Henikoff, Steven, Sullivan, Lucas B, Furlan, Scott N, Riddell, Stanley R

“…The interaction of the tumor necrosis factor receptor (TNFR) family member CD27 on naive CD8 T (Tn) cells with homotrimeric CD70 on antigen-presenting cells…”
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IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation by Zhang, Ping, Fleming, Peter, Andoniou, Christopher E, Waltner, Olivia G, Bhise, Shruti S, Martins, Jose Paulo, McEnroe, Benjamin A, Voigt, Valentina, Daly, Sheridan, Kuns, Rachel D, Ekwe, Adaeze P, Henden, Andrea S, Saldan, Alda, Olver, Stuart, Varelias, Antiopi, Smith, Corey, Schmidt, Christine R, Ensbey, Kathleen S, Legg, Samuel Rw, Sekiguchi, Tomoko, Minnie, Simone A, Gradwell, Mark, Wagenaar, Irma, Clouston, Andrew D, Koyama, Motoko, Furlan, Scott N, Kennedy, Glen A, Ward, E Sally, Degli-Esposti, Mariapia A, Hill, Geoffrey R, Tey, Siok-Keen

“…Endothelial function and integrity are compromised after allogeneic bone marrow transplantation (BMT), but how this affects immune responses broadly remains…”
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Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity by Minnie, Simone A, Waltner, Olivia G, Ensbey, Kathleen S, Nemychenkov, Nicole S, Schmidt, Christine R, Bhise, Shruti S, Legg, Samuel R W, Campoy, Gabriela, Samson, Luke D, Kuns, Rachel D, Zhou, Ting, Huck, John D, Vuckovic, Slavica, Zamora, Danniel, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate A, Lane, Steven W, Boeckh, Michael, Ring, Aaron M, Furlan, Scott N, Hill, Geoffrey R

“…Some hematological malignancies such as multiple myeloma are inherently resistant to immune-mediated antitumor responses, the cause of which remains unknown…”
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TIM-3 + CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies by Minnie, Simone A, Waltner, Olivia G, Zhang, Ping, Takahashi, Shuichiro, Nemychenkov, Nicole S, Ensbey, Kathleen S, Schmidt, Christine R, Legg, Samuel R W, Comstock, Melissa, Boiko, Julie R, Nelson, Ethan, Bhise, Shruti S, Wilkens, Alec B, Koyama, Motoko, Dhodapkar, Madhav V, Chesi, Marta, Riddell, Stanley R, Green, Damian J, Spencer, Andrew, Furlan, Scott N, Hill, Geoffrey R

“…Chronic antigen stimulation is thought to generate dysfunctional CD8 T cells. Here, we identify a CD8 T cell subset in the bone marrow tumor microenvironment…”
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Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease by Boiko, Julie R, Ensbey, Kathleen S, Schmidt, Christine R, Waltner, Olivia G, Minnie, Simone A, Furlan, Scott N, Hill, Geoffrey R

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320 - Single Cell RNA Sequencing Identifies IL-17- and CSF-1-Associated Pathologic Gene Expression Signatures in Blood during Chronic Graft-Versus-Host Disease by Boiko, Julie R, Ensbey, Kathleen S, Schmidt, Christine R, Waltner, Olivia G, Minnie, Simone A, Furlan, Scott N, Hill, Geoffrey R

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Abstract 1360: CD8 T cells display distinct trajectories of T cell exhaustion in the bone marrow of mice with multiple myeloma by Minnie, Simone A., Nemychenkov, Nicole S., Waltner, Olivia G., Ensbey, Kathleen S., Schmidt, Christine R., Bhise, Shruti S., Furlan, Scott N., Hill, Geoffrey R.

“…Abstract Multiple myeloma (MM) is the second most common hematological malignancy and despite the developments of novel therapies, it remains largely…”
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Alloantigen-Driven CD8 T Cell Exhaustion Is Reduced By PT-Cy and Subsequent Agonist Immunotherapy Drives Potent Graft-Versus-Myeloma Effects by Minnie, Simone A, Waltner, Olivia G., Ensbey, Kathleen S, Nemychenkov, Nicole S, Schmidt, Christine R, Bhise, Shruti S, Legg, Samuel R.W, Campoy, Gabriela, Samson, Luke D, Kuns, Rachel D, Vuckovic, Slavica, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate Ann, Lane, Steven W, Ring, Aaron M, Furlan, Scott N, Hill, Geoffrey R

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71 - Alloantigen-Driven CD8 T Cell Exhaustion Is Reduced By PT-Cy and Subsequent Agonist Immunotherapy Drives Potent Graft-Versus-Myeloma Effects by Minnie, Simone A, Waltner, Olivia G., Ensbey, Kathleen S, Nemychenkov, Nicole S, Schmidt, Christine R, Bhise, Shruti S, Legg, Samuel R.W, Campoy, Gabriela, Samson, Luke D, Kuns, Rachel D, Vuckovic, Slavica, Yeh, Albert, Spencer, Andrew, Koyama, Motoko, Markey, Kate Ann, Lane, Steven W, Ring, Aaron M, Furlan, Scott N, Hill, Geoffrey R

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