Search Results - "Walters, Matthew S."

Cilia Dysfunction in Lung Disease by Tilley, Ann E, Walters, Matthew S, Shaykhiev, Renat, Crystal, Ronald G

“…A characteristic feature of the human airway epithelium is the presence of ciliated cells bearing motile cilia, specialized cell surface projections containing…”
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Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway by Gomi, Kazunori, Arbelaez, Vanessa, Crystal, Ronald G, Walters, Matthew S

“…Airway basal cells (BC) function as stem/progenitor cells capable of differentiating into the luminal ciliated and secretory cells to replenish the airway…”
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Ontogeny and Biology of Human Small Airway Epithelial Club Cells by Zuo, Wu-Lin, Shenoy, Sushila A, Li, Sheng, O'Beirne, Sarah L, Strulovici-Barel, Yael, Leopold, Philip L, Wang, Guoqing, Staudt, Michelle R, Walters, Matthew S, Mason, Christopher, Kaner, Robert J, Mezey, Jason G, Crystal, Ronald G

“…Little is known about human club cells, dome-shaped cells with dense cytoplasmic granules and microvilli that represent the major secretory cells of the human…”
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The human airway epithelial basal cell transcriptome by Hackett, Neil R, Shaykhiev, Renat, Walters, Matthew S, Wang, Rui, Zwick, Rachel K, Ferris, Barbara, Witover, Bradley, Salit, Jacqueline, Crystal, Ronald G

“…The human airway epithelium consists of 4 major cell types: ciliated, secretory, columnar and basal cells. During natural turnover and in response to injury,…”
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Mitogen-Activated Protein Kinase Phosphatase 3 (MKP-3)-Deficient Mice Are Resistant to Diet-Induced Obesity by BIN FENG, PING JIAO, YNES HELOU, YUJIE LI, QIN HE, WALTERS, Matthew S, SALOMON, Arthur, HAIYAN XU

“…Mitogen-activated protein kinase phosphatase 3 (MKP-3) is a negative regulator of extracellular signal-related kinase signaling. Our laboratory recently…”
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Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease by Staudt, Michelle R, Buro-Auriemma, Lauren J, Walters, Matthew S, Salit, Jacqueline, Vincent, Thomas, Shaykhiev, Renat, Mezey, Jason G, Tilley, Ann E, Kaner, Robert J, Ho, Melisa W Y, Crystal, Ronald G

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Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2 by Ryan, Dorothy M, Vincent, Thomas L, Salit, Jacqueline, Walters, Matthew S, Agosto-Perez, Francisco, Shaykhiev, Renat, Strulovici-Barel, Yael, Downey, Robert J, Buro-Auriemma, Lauren J, Staudt, Michelle R, Hackett, Neil R, Mezey, Jason G, Crystal, Ronald G

“…Genome-wide association studies (GWAS) and candidate gene studies have identified a number of risk loci associated with the smoking-related disease COPD, a…”
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POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes by Zhou, Haixia, Brekman, Angelika, Zuo, Wu-Lin, Ou, Xuemei, Shaykhiev, Renat, Agosto-Perez, Francisco J, Wang, Rui, Walters, Matthew S, Salit, Jacqueline, Strulovici-Barel, Yael, Staudt, Michelle R, Kaner, Robert J, Mezey, Jason G, Crystal, Ronald G, Wang, Guoqing

“…In the process of seeking novel lung host defense regulators by analyzing genome-wide RNA sequence data from normal human airway epithelium, we detected…”
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Extracellular vesicles from human airway basal cells respond to cigarette smoke extract and affect vascular endothelial cells by Saxena, Ashish, Walters, Matthew S., Shieh, Jae-Hung, Shen, Ling-Bo, Gomi, Kazunori, Downey, Robert J., Crystal, Ronald G., Moore, Malcolm A. S.

“…The human airway epithelium lining the bronchial tree contains basal cells that proliferate, differentiate, and communicate with other components of their…”
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IRF7 Is Required for the Second Phase Interferon Induction during Influenza Virus Infection in Human Lung Epithelia by Wu, Wenxin, Zhang, Wei, Tian, Lili, Brown, Brent R, Walters, Matthew S, Metcalf, Jordan P

“…Influenza A virus (IAV) infection is a major cause of morbidity and mortality. Retinoic acid-inducible protein I (RIG-I) plays an important role in the…”
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RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium by Didon, Lukas, Zwick, Rachel K, Chao, Ion Wa, Walters, Matthew S, Wang, Rui, Hackett, Neil R, Crystal, Ronald G

“…Ciliated cells play a central role in cleansing the airways of inhaled contaminants. They are derived from basal cells that include the airway stem/progenitor…”
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Waterpipe smoking induces epigenetic changes in the small airway epithelium by Walters, Matthew S, Salit, Jacqueline, Ju, Jin Hyun, Staudt, Michelle R, Kaner, Robert J, Rogalski, Allison M, Sodeinde, Teniola B, Rahim, Riyaad, Strulovici-Barel, Yael, Mezey, Jason G, Almulla, Ahmad M, Sattar, Hisham, Mahmoud, Mai, Crystal, Ronald G

“…Waterpipe (also called hookah, shisha, or narghile) smoking is a common form of tobacco use in the Middle East. Its use is becoming more prevalent in Western…”
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Smoking-Associated Disordering of the Airway Basal Stem/Progenitor Cell Metabotype by Deeb, Ruba S, Walters, Matthew S, Strulovici-Barel, Yael, Chen, Qiuying, Gross, Steven S, Crystal, Ronald G

“…The airway epithelium is a complex pseudostratified multicellular layer lining the tracheobronchial tree, functioning as the primary defense against inhaled…”
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The Isolation and In Vitro Differentiation of Primary Fetal Baboon Tracheal Epithelial Cells for the Study of SARS-CoV-2 Host-Virus Interactions by Subramaniyan, Bharathiraja, Gurung, Sunam, Bodas, Manish, Moore, Andrew R, Larabee, Jason L, Reuter, Darlene, Georgescu, Constantin, Wren, Jonathan D, Myers, Dean A, Papin, James F, Walters, Matthew S

“…The mucociliary airway epithelium lines the human airways and is the primary site of host-environmental interactions in the lung. Following virus infection,…”
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Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals by Subramaniyan, Bharathiraja, Larabee, Jason L, Bodas, Manish, Moore, Andrew R, Burgett, Anthony W G, Myers, Dean A, Georgescu, Constantin, Wren, Jonathan D, Papin, James F, Walters, Matthew S

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), a global pandemic characterized by…”
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Smoking accelerates aging of the small airway epithelium by Walters, Matthew S, De, Bishnu P, Salit, Jacqueline, Buro-Auriemma, Lauren J, Wilson, Timothy, Rogalski, Allison M, Lief, Lindsay, Hackett, Neil R, Staudt, Michelle R, Tilley, Ann E, Harvey, Ben-Gary, Kaner, Robert J, Mezey, Jason G, Ashbridge, Beth, Moore, Malcolm A S, Crystal, Ronald G

“…Aging involves multiple biologically complex processes characterized by a decline in cellular homeostasis over time leading to a loss and impairment of…”
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Pulmonary Abnormalities in Young, Light-Use Waterpipe (Hookah) Smokers by Strulovici-Barel, Yael, Shaykhiev, Renat, Salit, Jacqueline, Deeb, Ruba S, Krause, Anja, Kaner, Robert J, Vincent, Thomas L, Agosto-Perez, Francisco, Wang, Guoqing, Hollmann, Charleen, Shanmugam, Vignesh, Almulla, Ahmad M, Sattar, Hisham, Mahmoud, Mai, Mezey, Jason G, Gross, Steven S, Staudt, Michelle R, Walters, Matthew S, Crystal, Ronald G

“…Waterpipes, also called hookahs, are currently used by millions of people worldwide. Despite the increasing use of waterpipe smoking, there is limited data on…”
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Role of KRAS in regulating normal human airway basal cell differentiation by Ogawa, Fumihiro, Walters, Matthew S, Shafquat, Afrah, O'Beirne, Sarah L, Kaner, Robert J, Mezey, Jason G, Zhang, Haijun, Leopold, Philip L, Crystal, Ronald G

“…KRAS is a GTPase that activates pathways involved in cell growth, differentiation and survival. In normal cells, KRAS-activity is tightly controlled, but with…”
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Hyperphosphorylation of Histone Deacetylase 2 by Alphaherpesvirus US3 Kinases by WALTERS, Matthew S, KINCHINGTON, Paul R, BANFIELD, Bruce W, SILVERSTEIN, Saul

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The RING Finger Domain of Varicella-Zoster Virus ORF61p Has E3 Ubiquitin Ligase Activity That Is Essential for Efficient Autoubiquitination and Dispersion of Sp100-Containing Nuclear Bodies by Walters, Matthew S, Kyratsous, Christos A, Silverstein, Saul J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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