Search Results - "Walters, Julian"

The Role of Bile After Roux-en-Y Gastric Bypass in Promoting Weight Loss and Improving Glycaemic Control by Pournaras, Dimitri J, Glicksman, Clare, Vincent, Royce P, Kuganolipava, Shophia, Alaghband-Zadeh, Jamie, Mahon, David, Bekker, Jan H.R, Ghatei, Mohammad A, Bloom, Stephen R, Walters, Julian R.F, Welbourn, Richard, le Roux, Carel W

“…Gastric bypass leads to the remission of type 2 diabetes independently of weight loss. Our hypothesis is that changes in bile flow due to the altered anatomy…”
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Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy by Walters, Julian R. F.

“…Key Points Bile acid diarrhoea (BAD) is a prevalent but poorly understood cause of chronic diarrhoea; bile acid malabsorption occurs in ileal disease, but the…”
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Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease by Hegyi, Peter, Maléth, Joszef, Walters, Julian R, Hofmann, Alan F, Keely, Stephen J

“…Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs where they primarily function in transporting digestive…”
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Making the Diagnosis of Bile Acid Diarrhea by Walters, Julian R.F.

“…Bile acid diarrhea is a frequent, treatable cause of functional diarrhea but is difficult to diagnose when the nuclear medicine seleno-taurohomocholic acid…”
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The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids by Sagar, Nidhi M., Duboc, Henri, Kay, Gemma L., Alam, Mohammad T., Wicaksono, Alfian N., Covington, James A., Quince, Christopher, Kokkorou, Margarita, Svolos, Vaios, Palmieri, Lola J., Gerasimidis, Konstantinos, Walters, Julian R. F., Arasaradnam, Ramesh P.

“…Bile acid diarrhoea (BAD) is a common disorder resulting from increased loss of bile acids (BAs), overlapping irritable bowel syndrome with diarrhoea (IBS-D)…”
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Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition by Arasaradnam, Ramesh P, Brown, Steven, Forbes, Alastair, Fox, Mark R, Hungin, Pali, Kelman, Lawrence, Major, Giles, O'Connor, Michelle, Sanders, Dave S, Sinha, Rakesh, Smith, Stephen Charles, Thomas, Paul, Walters, Julian R F

“…Chronic diarrhoea is a common problem, hence clear guidance on investigations is required. This is an updated guideline from 2003 for the investigations of…”
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CANADIAN ASSOCIATION OF GASTROENTEROLOGY CLINICAL PRACTICE GUIDELINE ON THE MANAGEMENT OF BILE ACID DIARRHEA by Sadowski, Daniel C, Camilleri, Michael, Chey, William D, Leontiadis, Grigorios I, Marshall, John K, Shaffer, Eldon A, Tse, Frances, Walters, Julian R.F

“…ABSTRACTBackground & AimsChronic diarrhea affects about 5% of the population overall. Altered bile acid metabolism is a common but frequently undiagnosed…”
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A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis by Walters, Julian R.F, Tasleem, Ali M, Omer, Omer S, Brydon, W. Gordon, Dew, Tracy, le Roux, Carel W

“…Background & Aims Primary (idiopathic) bile acid malabsorption (BAM) is a common, yet underrecognized, chronic diarrheal syndrome. Diagnosis is difficult…”
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Non-alcoholic fatty liver disease is associated with dysregulated bile acid synthesis and diarrhea: A prospective observational study by Appleby, Richard N, Moghul, Iman, Khan, Shahid, Yee, Michael, Manousou, Pinelope, Neal, Tracy Dew, Walters, Julian R F

“…Non-alcoholic fatty liver disease (NAFLD) may be associated with changes in bile acid (BA) metabolism. Hepatic BA production, measured by serum levels of the…”
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Chronic diarrhea, bile acids, and Clostridia by Walters, Julian Rf, Marchesi, Julian R

“…Excessive fecal bile acid (BA) loss causes symptoms in a large proportion of people diagnosed with irritable bowel syndrome with diarrhea, a common functional…”
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Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis by Ovadia, Caroline, Perdones‐Montero, Alvaro, Spagou, Konstantina, Smith, Ann, Sarafian, Magali H., Gomez‐Romero, Maria, Bellafante, Elena, Clarke, Louise C.D., Sadiq, Fouzia, Nikolova, Vanya, Mitchell, Alice, Dixon, Peter H., Santa‐Pinter, Natalie, Wahlström, Annika, Abu‐Hayyeh, Shadi, Walters, Julian R.F., Marschall, Hanns‐Ulrich, Holmes, Elaine, Marchesi, Julian R., Williamson, Catherine

“…Pregnancy is associated with progressive hypercholanemia, hypercholesterolemia, and hypertriglyceridemia, which can result in metabolic disease in susceptible…”
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Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy by Ovadia, Caroline, Perdones-Montero, Alvaro, Fan, Hei Man, Mullish, Benjamin H., McDonald, Julie A. K., Papacleovoulou, Georgia, Wahlström, Annika, Ståhlman, Marcus, Tsakmaki, Anastasia, Clarke, Louise C. D., Sklavounos, Alexandros, Dixon, Peter H., Bewick, Gavin A., Walters, Julian R. F., Marschall, Hanns-Ulrich, Marchesi, Julian R., Williamson, Catherine

“…Ursodeoxycholic acid (UDCA) treatment can reduce itch and lower endogenous serum bile acids in intrahepatic cholestasis of pregnancy (ICP). We sought to…”
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The role of bile acids and their TGR5 receptor in irritable bowel syndrome and diarrhoea by Walters, Julian R.F.

“…This commentary looks at recent findings relating to bile acids in patients with irritable bowel syndrome with diarrhoea (IBS-D). Bile acid diarrhoea is…”
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Managing bile acid diarrhea: aspects of contention by Walters, Julian R F, Sikafi, Rafid

“…Bile acid diarrhea is a common cause of bowel symptoms and often goes unrecognized or misdiagnosed. Many aspects of management remain contentious. The primary,…”
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A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid Pathways by Quraishi, Mohammed Nabil, Acharjee, Animesh, Beggs, Andrew D, Horniblow, Richard, Tselepis, Chris, Gkoutos, Georgios, Ghosh, Subrata, Rossiter, A E, Loman, Nicholas, van Schaik, Willem, Withers, David, Walters, Julian R F, Hirschfield, Gideon M, Iqbal, Tariq H

“…Abstract Background Although a majority of patients with PSC have colitis [PSC-IBD; primary sclerosing cholangitis-inflammatory bowel disease], this is…”
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Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain by Akbar, Ayesha, Yiangou, Yiangos, Facer, Paul, Brydon, W G, Walters, Julian R F, Anand, Praveen, Ghosh, Subrata

“…Transient receptor potential vanilloid type 1 (TRPV1) has been shown to play an important role in visceral hypersensitivity. A significant proportion of…”
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Lessons from a trial of colesevelam for bile acid diarrhoea by Walters, Julian R F

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Randomised clinical trial: significant biochemical and colonic transit effects of the farnesoid X receptor agonist tropifexor in patients with primary bile acid diarrhoea by Camilleri, Michael, Nord, Sara Linker, Burton, Duane, Oduyebo, Ibironke, Zhang, Yiming, Chen, Jin, Im, Koeun, Bhad, Prafulla, Badman, Michael K., Sanders, David S., Walters, Julian R. F.

“…Summary Background In primary bile acid diarrhoea, feedback by farnesoid X receptor (FXR) and fibroblast growth hormone 19 (FGF19) on hepatic bile acid…”
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Letter: long‐term treatment of severe bile acid diarrhoea—obeticholic acid can normalise SeHCAT retention by Walters, Julian R. F.

“…Linked Content This article is linked to Damsgaard et al papers. To view these articles visit https://doi.org/10.1111/apt.14533 and…”
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The Farnesoid X Receptor: Good for BAD by Keely, Stephen J, Walters, Julian R.F

“…Diarrhea is a feature of several chronic intestinal disorders that are associated with increased delivery of bile acids into the colon. Although the prevalence…”
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