Search Results - "Walters, Jennifer"
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Review of preclinical studies on pediatric general anesthesia-induced developmental neurotoxicity
Published in Neurotoxicology and teratology (01-03-2017)“…Abstract Thousands of infants and children undergo complicated surgical procedures that require prolonged periods of anesthesia and/or sedation each year. A…”
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An emerging role of STriatal-Enriched protein tyrosine Phosphatase in hyperexcitability-associated brain disorders
Published in Neurobiology of disease (01-10-2024)“…STriatal-Enriched protein tyrosine Phosphatase (STEP) is a brain-specific tyrosine phosphatase that is associated with numerous neurological and…”
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3
Access to Diverse Oxygen Heterocycles via Oxidative Rearrangement of Benzylic Tertiary Alcohols
Published in Organic letters (15-04-2016)“…A facile method for the synthesis of challenging medium-sized cyclic ethers has been developed via a novel oxidative rearrangement of benzylic tertiary…”
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Services to domestic minor victims of sex trafficking: Opportunities for engagement and support
Published in Children and youth services review (01-07-2015)“…Human trafficking of young people is a social problem of growing concern. This paper reports selected findings from an evaluation of three programs serving…”
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Evaluation of optimal treatment for urinary tract infections in outpatient clinics at an academic medical center: Opportunities for antimicrobial stewardship
Published in American journal of infection control (01-01-2022)“…•Differences in prescribing of outpatient antibiotics for UTIs exist between provider and clinic types.•Beta-lactam allergies did not influence prescribing…”
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Heterocyclic group transfer reactions with I(iii) N -HVI reagents: access to N -alkyl(heteroaryl)onium salts via olefin aminolactonization
Published in Chemical science (Cambridge) (12-04-2021)“…Pyridinium and related -alkyl(heteroaryl)onium salts are versatile synthetic intermediates in organic chemistry, with applications ranging from ring…”
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Basolateral amygdala corticotropin-releasing factor receptor type 1 regulates context-cocaine memory strength during reconsolidation in a sex-dependent manner
Published in Neuropharmacology (01-12-2021)“…The basolateral amygdala (BLA) is a critical brain region for cocaine-memory reconsolidation. Corticotropin-releasing factor receptor type 1 (CRFR1) is densely…”
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Pharmacological inhibition of STriatal‐Enriched protein tyrosine Phosphatase by TC‐2153 reduces hippocampal excitability and seizure propensity
Published in Epilepsia (Copenhagen) (01-05-2022)“…Objective STriatal‐Enriched protein tyrosine Phosphatase (STEP) is a brain‐specific tyrosine phosphatase. Membrane‐bound STEP61 is the only isoform expressed…”
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Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy
Published in Neurobiology of disease (01-10-2018)“…Neuronal Kv7/KCNQ channels are voltage-gated potassium channels composed of Kv7.2/KCNQ2 and Kv7.3/KCNQ3 subunits. Enriched at the axonal membrane, they…”
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The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats
Published in Toxicology and applied pharmacology (01-12-2015)“…This study sought to investigate the effects of environmentally relevant gestational followed by continued chronic exposure to the herbicide, atrazine, on…”
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Sevoflurane exposure has minimal effect on cognitive function and does not alter microglial activation in adult monkeys
Published in Neurotoxicology (Park Forest South) (01-03-2019)“…•An 8-hour exposure to sevoflurane did not cause an increase in neuroinflammation as measured by [18F]-FEPPA in aged monkeys.•Extended exposure to sevoflurane…”
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Regions of the basal ganglia and primary olfactory system are most sensitive to neurodegeneration after extended sevoflurane anesthesia in the perinatal rat
Published in Neurotoxicology and teratology (01-07-2020)“…Extended general anesthesia early in life is neurotoxic in multiple species. However, little is known about the temporal progression of neurodegeneration after…”
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Polycystin 2 is increased in disease to protect against stress-induced cell death
Published in Scientific reports (15-01-2020)“…Polycystin 2 (PC2 or TRPP1, formerly TRPP2) is a calcium-permeant Transient Receptor Potential (TRP) cation channel expressed primarily on the endoplasmic…”
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(Poly)cationic λ3‐Iodane‐Mediated Oxidative Ring Expansion of Secondary Alcohols
Published in European journal of organic chemistry (29-03-2018)“…Herein, a simplified approach to the synthesis of medium‐ring ethers through the electrophilic activation of secondary alcohols with (poly)cationic λ3‐iodanes…”
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(Poly)cationic λ 3 -Iodane Mediated Oxidative Ring Expansion of Secondary Alcohols
Published in European journal of organic chemistry (29-03-2018)“…Herein, we report a simplified approach to the synthesis of medium-ring ethers through the electrophilic activation of secondary alcohols with (poly)cationic λ…”
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Acetyl-l-carnitine does not prevent neurodegeneration in a rodent model of prolonged neonatal anesthesia
Published in Neurotoxicology and teratology (01-07-2020)“…Many studies have shown that prolonged or repeated use of general anesthesia early in life can cause an increase in neurodegeneration and lasting changes in…”
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17
Approaches used by employee assistance programs to address perpetration of intimate partner violence
Published in Violence and victims (01-01-2012)“…Employee Assistance Programs (EAPs) are workplace resources available to employees with problems impacting work performance. EAPs are well-positioned to…”
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Single and repeated exposures to the volatile anesthetic isoflurane do not impair operant performance in aged rats
Published in Neurotoxicology (Park Forest South) (01-09-2016)“…The effects of isoflurane on operant performance in aged rats were assessed.Operant tasks measured behavioral inhibition, counting, sequential learning, and…”
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Are You A Leader? How We Learned to Stop Asking
Published in Theory into practice (02-10-2015)“…Smith College initiated an ePortfolio pilot project to guide students in documenting key learning experiences and in linking those experiences to Smith's…”
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Substance Use by Soldiers Who Abuse Their Spouses
Published in Violence against women (01-11-2010)“…Data on 7,424 soldier spouse abuse offenders were analyzed to determine the prev alence of substance use during abusiv e incidents, and to examine differences…”
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