Search Results - "Walters, Elisabetta"

Quantitation of Circulating Mycobacterium tuberculosis Antigens by Nanopore Biosensing in Children Evaluated for Pulmonary Tuberculosis in South Africa by Wang, Xiaoqin, Wei, Xiaojun, van der Zalm, Marieke M., Zhang, Zehui, Subramanian, Nandhini, Demers, Anne-Marie, Ghimenton Walters, Elisabetta, Hesseling, Anneke, Liu, Chang

“…Nanopore sensing of proteomic biomarkers lacks accuracy due to the ultralow abundance of targets, a wide variety of interferents in clinical samples, and the…”
Get full text

Utility of host markers detected in Quantiferon supernatants for the diagnosis of tuberculosis in children in a high-burden setting by Chegou, Novel N, Detjen, Anne K, Thiart, Lani, Walters, Elisabetta, Mandalakas, Anna M, Hesseling, Anneke C, Walzl, Gerhard

“…The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified…”
Get full text

Complementary surveillance strategies are needed to better characterise the epidemiology, care pathways and treatment outcomes of tuberculosis in children by du Preez, Karen, Schaaf, H Simon, Dunbar, Rory, Walters, Elisabetta, Swartz, Alvera, Solomons, Regan, Hesseling, Anneke C

“…Tuberculosis (TB) in young and HIV-infected children is frequently diagnosed at hospital level. In settings where general hospitals do not function as TB…”
Get full text

Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis by Gunasekera, Kenneth S, Marcy, Olivier, Muñoz, Johanna, Lopez-Varela, Elisa, Sekadde, Moorine P, Franke, Molly F, Bonnet, Maryline, Ahmed, Shakil, Amanullah, Farhana, Anwar, Aliya, Augusto, Orvalho, Aurilio, Rafaela Baroni, Banu, Sayera, Batool, Iraj, Brands, Annemieke, Cain, Kevin P, Carratalá-Castro, Lucía, Caws, Maxine, Click, Eleanor S, Cranmer, Lisa M, García-Basteiro, Alberto L, Hesseling, Anneke C, Huynh, Julie, Kabir, Senjuti, Lecca, Leonid, Mandalakas, Anna, Mavhunga, Farai, Myint, Aye Aye, Myo, Kyaw, Nampijja, Dorah, Nicol, Mark P, Orikiriza, Patrick, Palmer, Megan, Sant'Anna, Clemax Couto, Siddiqui, Sara Ahmed, Smith, Jonathan P, Song, Rinn, Thuong Thuong, Nguyen Thuy, Ung, Vibol, van der Zalm, Marieke M, Verkuijl, Sabine, Viney, Kerri, Walters, Elisabetta G, Warren, Joshua L, Zar, Heather J, Marais, Ben J, Graham, Stephen M, Debray, Thomas P A, Cohen, Ted, Seddon, James A

“…Many children with pulmonary tuberculosis remain undiagnosed and untreated with related high morbidity and mortality. Recent advances in childhood tuberculosis…”
Get more information

Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy by Walters, Elisabetta, Cotton, Mark F, Rabie, Helena, Schaaf, H Simon, Walters, Lourens O, Marais, Ben J

“…The tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are poorly controlled in sub-Saharan Africa, where highly active antiretroviral…”
Get full text

Optimising computer aided detection to identify intra-thoracic tuberculosis on chest x-ray in South African children by Palmer, Megan, Seddon, James A, van der Zalm, Marieke M, Hesseling, Anneke C, Goussard, Pierre, Schaaf, H Simon, Morrison, Julie, van Ginneken, Bram, Melendez, Jaime, Walters, Elisabetta, Murphy, Keelin

“…Diagnostic tools for paediatric tuberculosis remain limited, with heavy reliance on clinical algorithms which include chest x-ray. Computer aided detection…”
Get full text

Validation of biomarkers for distinguishing Mycobacterium tuberculosis from non-tuberculous mycobacteria using gas chromatography-mass spectrometry and chemometrics by Dang, Ngoc A, Kuijper, Sjoukje, Walters, Elisabetta, Claassens, Mareli, van Soolingen, Dick, Vivo-Truyols, Gabriel, Janssen, Hans-Gerd, Kolk, Arend H J

“…Tuberculosis (TB) remains a major international health problem. Rapid differentiation of Mycobacterium tuberculosis complex (MTB) from non-tuberculous…”
Get full text

Diagnostic Advances in Childhood Tuberculosis-Improving Specimen Collection and Yield of Microbiological Diagnosis for Intrathoracic Tuberculosis by Wobudeya, Eric, Bonnet, Maryline, Walters, Elisabetta Ghimenton, Nabeta, Pamela, Song, Rinn, Murithi, Wilfred, Mchembere, Walter, Dim, Bunnet, Taguebue, Jean-Voisin, Orne-Gliemann, Joanna, Nicol, Mark P, Marcy, Olivier

“…There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The paucibacillary nature of the disease, challenges in sample collection…”
Get full text

UMOYA: a prospective longitudinal cohort study to evaluate novel diagnostic tools and to assess long-term impact on lung health in South African children with presumptive pulmonary TB-a study protocol by Dewandel, Isabelle, van Niekerk, Margaret, Ghimenton-Walters, Elisabetta, Palmer, Megan, Anthony, Michaile G, McKenzie, Carla, Croucamp, Rolanda, Alter, Galit, Demers, Anne-Marie, van Zyl, Gert, Claassen, Mathilda, Goussard, Pierre, Swanepoel, Ruan, Hoddinott, Graeme, Bosch, Corne, Dunbar, Rory, Allwood, Brian, McCollum, Eric D, Schaaf, H Simon, Hesseling, Anneke C, van der Zalm, Marieke M

“…Despite a high paediatric tuberculosis (TB) burden globally, sensitive and specific diagnostic tools are lacking. In addition, no data exist on the impact of…”
Get full text

Optimizing the Threshold to Treat Children for Latent Tuberculosis Infection: A North-East England Experience by Porter, George James, Whyte, Martin, Walters, Elisabetta Ghimenton, Owens, Stephen

“…We assessed the impact of the updated guidelines on tuberculin skin test interpretation in the North East of England. Data on 241 children screened for latent…”
Get full text

Optimizing the Threshold to Treat Children for Latent Tuberculosis Infection: A North-East England Experience by Porter, George James, Whyte, Martin, Walters, Elisabetta Ghimenton, Owens, Stephen

“…We assessed the impact of the updated guidelines on tuberculin skin test interpretation in the North East of England. Data on 241 children screened for latent…”
Get full text

Development of a Treatment-decision Algorithm for Human Immunodeficiency Virus–uninfected Children Evaluated for Pulmonary Tuberculosis by Gunasekera, Kenneth S, Walters, Elisabetta, van der Zalm, Marieke M, Palmer, Megan, Warren, Joshua L, Hesseling, Anneke C, Cohen, Ted, Seddon, James A

“…Abstract Background Limitations in the sensitivity and accessibility of diagnostic tools for childhood tuberculosis contribute to the substantial gap between…”
Get full text

EDITORIAL COMMENTARY: Improving Children's Access to New Tuberculosis Diagnostic Tools Starts With the Collection of Appropriate Specimens by Detjen, Anne K., Walters, Elisabetta

Get full text

Clinical Evaluation of a Blood Assay to Diagnose Paucibacillary Tuberculosis via Bacterial Antigens by Liu, Chang, Lyon, Christopher J, Bu, Yang, Deng, Zaian, Walters, Elisabetta, Li, Yan, Zhang, Liqun, Hesseling, Anneke C, Graviss, Edward A, Hu, Ye

“…The diagnosis of active tuberculosis (TB) cases primarily relies on methods that detect ( ) bacilli or their DNA in patient samples (e.g., mycobacterial…”
Get full text

Xpert MTB/RIF on Stool Is Useful for the Rapid Diagnosis of Tuberculosis in Young Children With Severe Pulmonary Disease by Walters, Elisabetta, van der Zalm, Marieke Magrieta, Palmer, Megan, Bosch, Corné, Demers, Anne-Marie, Draper, Heather, Goussard, Pierre, Schaaf, Hendrik Simon, Friedrich, Sven Olaf, Whitelaw, Andrew, Warren, Robin, Gie, Robert P, Hesseling, Anneke C

“…BACKGROUND:Tuberculosis (TB) continues to result in high morbidity and mortality in children from resource-limited settings. Diagnostic challenges, including…”
Get full text

Recurrent Tuberculosis Treatment Episodes in Children Presenting With Presumptive Pulmonary Tuberculosis in Cape Town, South Africa by Mckenzie, Carla, Schaaf, H. Simon, Croucamp, Rolanda, Palmer, Megan, Bosch, Corné, Goussard, Pierre, Rabie, Helena, Whitelaw, Andrew, Hesseling, Anneke C., van Niekerk, Margaret, van der Zalm, Marieke M., Ghimenton-Walters, Elisabetta

Get full text

The Diagnostic Accuracy of Chest Radiographic Features for Pediatric Intrathoracic Tuberculosis by Palmer, Megan, Gunasekera, Kenneth S, van der Zalm, Marieke M, Morrison, Julie, Simon Schaaf, H, Goussard, Pierre, Hesseling, Anneke C, Walters, Elisabetta, Seddon, James A

“…Abstract Introduction The chest radiograph (CR) remains a key tool in the diagnosis of pediatric tuberculosis (TB). In children with presumptive intrathoracic…”
Get full text

GeneXpert MTB/RIF on bronchoalveolar lavage samples in children with suspected complicated intrathoracic tuberculosis: A pilot study by Walters, Elisabetta, Goussard, Pierre, Bosch, Corne, Hesseling, Anneke C., Gie, Robert P.

“…Summary Background Children with complicated intrathoracic tuberculosis (TB) require rapid confirmation of TB diagnosis and of drug susceptibility to institute…”
Get full text

Stool Culture for Diagnosis of Pulmonary Tuberculosis in Children by Walters, Elisabetta, Demers, Anne-Marie, van der Zalm, Marieke M, Whitelaw, Andrew, Palmer, Megan, Bosch, Corné, Draper, Heather R, Gie, Robert P, Hesseling, Anneke C

“…Bacteriological confirmation of is achieved in the minority of young children with tuberculosis (TB), since specimen collection is resource intensive and…”
Get full text

Rapid Diagnosis of Pediatric Intrathoracic Tuberculosis From Stool Samples Using the Xpert MTB/RIF Assay: A Pilot Study by Walters, Elisabetta, Gie, Robert Peter, Hesseling, Anneke Catharina, Friedrich, Sven Olaf, Diacon, Andreas Henri

Get full text