Search Results - "Walters, Dewi J."

The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists by Lunniss, Gillian E., Barnes, Ashley A., Barton, Nick, Biagetti, Matteo, Bianchi, Federica, Blowers, Stephen M., Caberlotto, Laura L., Emmons, Amanda, Holmes, Ian P., Montanari, Dino, Norris, Roz, Puckey, Gemma V., Walters, Dewi J., Watson, Steve P., Willis, John

“…The optimisation of diamide 1 to amine 2, a soluble and selective NPY Y2 receptor antagonist with enhanced CNS exposure is described. The identification and…”
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The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists by Lunniss, Gillian E., Barnes, Ashley A., Barton, Nick, Biagetti, Matteo, Bianchi, Federica, Blowers, Stephen M., Caberlotto, Laura, Emmons, Amanda, Holmes, Ian P., Montanari, Dino, Norris, Ros, Walters, Dewi J., Watson, Steve P.

“…Identification of novel small molecule NPY Y2 antagonist 3 and optimisation through to 36 is described. A novel small molecule NPY Y2 antagonist (3) identified…”
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