Search Results - "Walter Wray, D"
-
1
Ultrasound Assessment of Flow-Mediated Dilation
Published in Hypertension (Dallas, Tex. 1979) (01-05-2010)“…Developed in 1992, the flow-mediated dilation test is now the most commonly used noninvasive assessment of vascular endothelial function in humans. Since its…”
Get full text
Journal Article -
2
Assessment of resistance vessel function in human skeletal muscle: guidelines for experimental design, Doppler ultrasound, and pharmacology
Published in American journal of physiology. Heart and circulatory physiology (01-02-2020)“…The introduction of duplex Doppler ultrasound almost half a century ago signified a revolutionary advance in the ability to assess limb blood flow in humans…”
Get more information
Journal Article -
3
Vascular function and endothelin-1: tipping the balance between vasodilation and vasoconstriction
Published in Journal of applied physiology (1985) (01-02-2017)“…Endothelin-1 (ET-1), a potent vasoconstrictor secreted by vascular endothelial cells, has been implicated in the pathophysiology of numerous cardiovascular…”
Get full text
Journal Article -
4
Exercise intolerance in heart failure with preserved ejection fraction: Causes, consequences and the journey towards a cure
Published in Experimental physiology (01-04-2024)“…Heart failure with preserved ejection fraction (HFpEF) accounts for over 50% of all heart failure cases nationwide and continues to rise in its prevalence. The…”
Get full text
Journal Article -
5
Acute Reversal of Endothelial Dysfunction in the Elderly After Antioxidant Consumption
Published in Hypertension (Dallas, Tex. 1979) (01-04-2012)“…Aging is associated with a pro-oxidant state and a decline in endothelial function. Whether acute, enteral antioxidant treatment can reverse this decrement in…”
Get full text
Journal Article -
6
On the contribution of group III and IV muscle afferents to the circulatory response to rhythmic exercise in humans
Published in The Journal of physiology (01-08-2011)“…Non‐technical summary We investigated the role of thin fibre muscle afferents in the circulatory response to exercise in humans. The results not only document…”
Get full text
Journal Article -
7
Exercise-induced brachial artery vasodilation: effects of antioxidants and exercise training in elderly men
Published in American journal of physiology. Heart and circulatory physiology (01-02-2010)“…Aging, vascular function, and exercise are thought to have a common link in oxidative stress. Of the 28 subjects studied (young, 26 +/- 2 yr; old, 71 +/- 6…”
Get more information
Journal Article -
8
No effect of acute tetrahydrobiopterin (BH 4 ) supplementation on vascular dysfunction in the old
Published in Journal of applied physiology (1985) (01-03-2022)“…As a deficiency in tetrahydrobiopterin (BH ), a cofactor for endothelial nitric oxide synthase, has been implicated in the age-related decline in vascular…”
Get full text
Journal Article -
9
The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure
Published in Medicine and science in sports and exercise (01-03-2016)“…BACKGROUNDSensitization of mechanosensitive afferents, which contribute to the exercise pressor reflex, has been recognized as a characteristic of patients…”
Get full text
Journal Article -
10
Group III/IV muscle afferents impair limb blood in patients with chronic heart failure
Published in International journal of cardiology (15-06-2014)“…Abstract Objective To better understand the hemodynamic and autonomic reflex abnormalities in heart-failure patients (HF), we investigated the influence of…”
Get full text
Journal Article -
11
Progressive handgrip exercise: evidence of nitric oxide-dependent vasodilation and blood flow regulation in humans
Published in American journal of physiology. Heart and circulatory physiology (01-03-2011)“…In the peripheral circulation, nitric oxide (NO) is released in response to shear stress across vascular endothelial cells. We sought to assess the degree to…”
Get more information
Journal Article -
12
Does Brachial Artery Flow–Mediated Vasodilation Provide a Bioassay for NO?
Published in Hypertension (Dallas, Tex. 1979) (01-08-2013)“…This study sought to better define the role of NO in brachial artery flow–mediated vasodilation (FMD) in young, healthy humans. Brachial artery blood velocity…”
Get full text
Journal Article -
13
Limb-specific differences in flow-mediated dilation: the role of shear rate
Published in Journal of applied physiology (1985) (01-09-2007)“…1 Department of Medicine, University of California, San Diego, La Jolla, California; and 2 Departments of Medicine and of Exercise and Sport Science,…”
Get full text
Journal Article -
14
Human skeletal muscle intracellular oxygenation: the impact of ambient oxygen availability
Published in The Journal of physiology (01-03-2006)“…Intracellular oxygen (O 2 ) availability and the impact of ambient hypoxia have far reaching ramifications in terms of cell signalling and homeostasis;…”
Get full text
Journal Article -
15
Oral antioxidants and cardiovascular health in the exercise-trained and untrained elderly: a radically different outcome
Published in Clinical science (1979) (01-03-2009)“…Both antioxidant supplementation and exercise training have been identified as interventions which may reduce oxidative stress and thus improve cardiovascular…”
Get more information
Journal Article -
16
Ascorbic acid improves brachial artery vasodilation during progressive handgrip exercise in the elderly through a nitric oxide-mediated mechanism
Published in American journal of physiology. Heart and circulatory physiology (15-03-2016)“…The proposed mechanistic link between the age-related attenuation in vascular function and free radicals is an attractive hypothesis; however, direct evidence…”
Get more information
Journal Article -
17
Exercise-induced brachial artery blood flow and vascular function is impaired in systemic sclerosis
Published in American journal of physiology. Heart and circulatory physiology (01-12-2016)“…Systemic sclerosis (SSc) is a rare autoimmune disease characterized by debilitating fibrosis and vascular dysfunction; however, little is known about the…”
Get more information
Journal Article -
18
Differential effects of aging on limb blood flow in humans
Published in American journal of physiology. Heart and circulatory physiology (01-01-2006)“…Aging appears to attenuate leg blood flow during exercise; in contrast, such data are scant and do not support this contention in the arm. Therefore, to…”
Get more information
Journal Article -
19
Oral antioxidants improve leg blood flow during exercise in patients with chronic obstructive pulmonary disease
Published in American journal of physiology. Heart and circulatory physiology (01-09-2015)“…The consequence of elevated oxidative stress on exercising skeletal muscle blood flow as well as the transport and utilization of O2 in patients with chronic…”
Get more information
Journal Article -
20
Aging affects vascular structure and function in a limb-specific manner
Published in Journal of applied physiology (1985) (01-11-2008)“…1 Department of Medicine, University of California, San Diego, La Jolla, California; 2 Department of Medicine, Division of Geriatrics, University of Utah, Salt…”
Get full text
Journal Article