Search Results - "Walston, Jeremy D."

Management of frailty: opportunities, challenges, and future directions by Dent, Elsa, Martin, Finbarr C, Bergman, Howard, Woo, Jean, Romero-Ortuno, Roman, Walston, Jeremy D

“…Frailty is a complex age-related clinical condition characterised by a decline in physiological capacity across several organ systems, with a resultant…”
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Underlying Vulnerabilities to the Cytokine Storm and Adverse COVID-19 Outcomes in the Aging Immune System by Nidadavolu, Lolita S, Walston, Jeremy D

“…Abstract Older adults are far more vulnerable to adverse health outcomes and mortality after contracting COVID-19. There are likely multiple age-related…”
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Frailty in Older Adults: A Nationally Representative Profile in the United States by Bandeen-Roche, Karen, Seplaki, Christopher L, Huang, Jin, Buta, Brian, Kalyani, Rita R, Varadhan, Ravi, Xue, Qian-Li, Walston, Jeremy D, Kasper, Judith D

“…Frailty assessment provides a means of identifying older adults most vulnerable to adverse outcomes. Attention to frailty in clinical practice is more likely…”
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Frailty assessment instruments: Systematic characterization of the uses and contexts of highly-cited instruments by Buta, Brian J, Walston, Jeremy D, Godino, Job G, Park, Minsun, Kalyani, Rita R, Xue, Qian-Li, Bandeen-Roche, Karen, Varadhan, Ravi

“…Highlights • Frailty tool proliferation is a challenge for selecting an assessment instrument. • We categorized how the nine most-cited frailty instruments…”
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Development of a Claims-based Frailty Indicator Anchored to a Well-established Frailty Phenotype by Segal, Jodi B., Chang, Hsien-Yen, Du, Yu, Walston, Jeremy D., Carlson, Michelle C., Varadhan, Ravi

“…Fried and colleagues described a frailty phenotype measured in the Cardiovascular Health Study (CHS). This phenotype is manifest when ≥3 of the following are…”
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Frailty and cardiovascular outcomes in the National Health and Aging Trends Study by Damluji, Abdulla A, Chung, Shang-En, Xue, Qian-Li, Hasan, Rani K, Moscucci, Mauro, Forman, Daniel E, Bandeen-Roche, Karen, Batchelor, Wayne, Walston, Jeremy D, Resar, Jon R, Gerstenblith, Gary

“…Abstract Aims Physical frailty is a commonly encountered geriatric syndrome among older adults without coronary heart disease (CHD). The impact of frailty on…”
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Frailty for Surgeons: Review of a National Institute on Aging Conference on Frailty for Specialists by Robinson, Thomas N., MD, MS, FACS, Walston, Jeremy D., MD, Brummel, Nathan E., MD, MSCI, Deiner, Stacie, MD, MS, Brown, Charles H., MD, MHS, Kennedy, Maura, MD, MPH, Hurria, Arti, MD

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Brain Renin-Angiotensin System at the Intersect of Physical and Cognitive Frailty by Cosarderelioglu, Caglar, Nidadavolu, Lolita S, George, Claudene J, Oh, Esther S, Bennett, David A, Walston, Jeremy D, Abadir, Peter M

“…The renin-angiotensin system (RAS) was initially considered to be part of the endocrine system regulating water and electrolyte balance, systemic vascular…”
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Individual Frailty Components and Mortality in Kidney Transplant Recipients by McAdams-DeMarco, Mara A, Ying, Hao, Olorundare, Israel, King, Elizabeth A, Haugen, Christine, Buta, Brian, Gross, Alden L, Kalyani, Rita, Desai, Niraj M, Dagher, Nabil N, Lonze, Bonnie E, Montgomery, Robert A, Bandeen-Roche, Karen, Walston, Jeremy D, Segev, Dorry L

“…BACKGROUNDFrailty increases early hospital readmission and mortality risk among kidney transplantation (KT) recipients. Although frailty represents a high-risk…”
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Frailty and Access to Kidney Transplantation by Haugen, Christine E, Chu, Nadia M, Ying, Hao, Warsame, Fatima, Holscher, Courtenay M, Desai, Niraj M, Jones, Miranda R, Norman, Silas P, Brennan, Daniel C, Garonzik-Wang, Jacqueline, Walston, Jeremy D, Bingaman, Adam W, Segev, Dorry L, McAdams-DeMarco, Mara

“…Frailty, a syndrome distinct from comorbidity and disability, is clinically manifested as a decreased resistance to stressors and is present in up to 35% of…”
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Delirium After Spine Surgery in Older Adults: Incidence, Risk Factors, and Outcomes by Brown IV, Charles H., LaFlam, Andrew, Max, Laura, Wyrobek, Julie, Neufeld, Karin J., Kebaish, Khaled M., Cohen, David B., Walston, Jeremy D., Hogue, Charles W., Riley, Lee H.

“…Objectives To characterize the incidence, risk factors, and consequences of delirium in older adults undergoing spine surgery. Design Prospective observational…”
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Frailty and Postkidney Transplant Health-Related Quality of Life by McAdams-DeMarco, Mara A, Olorundare, Israel O, Ying, Hao, Warsame, Fatima, Haugen, Christine E, Hall, Rasheeda, Garonzik-Wang, Jacqueline M, Desai, Niraj M, Walston, Jeremy D, Norman, Silas P, Segev, Dorry L

“…BACKGROUNDHealth-related quality of life (HRQOL) reflects a patient’s disease burden, treatment effectiveness, and health status and is summarized by physical,…”
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Frailty Among Older Adults With Acute Myocardial Infarction and Outcomes From Percutaneous Coronary Interventions by Damluji, Abdulla A, Huang, Jin, Bandeen-Roche, Karen, Forman, Daniel E, Gerstenblith, Gary, Moscucci, Mauro, Resar, Jon R, Varadhan, Ravi, Walston, Jeremy D, Segal, Jodi B

“…Background Frailty is a predictor of adverse outcomes after acute myocardial infarction (AMI). Methods and Results We estimated the prevalence of frailty among…”
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Identification and characterization of a functional mitochondrial angiotensin system by Abadir, Peter M, Foster, D. Brian, Crow, Michael, Cooke, Carol A, Rucker, Jasma J, Jain, Alka, Smith, Barbara J, Burks, Tyesha N, Cohn, Ronald D, Fedarko, Neal S, Carey, Robert M, O’Rourke, Brian, Walston, Jeremy D

“…The renin-angiotensin (Ang) system regulates multiple physiological functions through Ang II type 1 and type 2 receptors. Prior studies suggest an…”
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The transition to family caregiving and its effect on biomarkers of inflammation by Roth, David L., Haley, William E., Sheehan, Orla C., Huang, Jin, Rhodes, J. David, Durda, Peter, Howard, Virginia J., Walston, Jeremy D., Cushman, Mary

“…Chronic stress has been widely proposed to increase systemic inflammation, a pathway that may link stress with a heightened risk for many diseases. The chronic…”
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Inflammation and Frailty in Older Women by Leng, Sean X., Xue, Qian-Li, Tian, Jing, Walston, Jeremy D., Fried, Linda P.

“…OBJECTIVES: To evaluate relationships between white blood cell (WBC) count and interleukin‐6 (IL‐6) and prevalent frailty. DESIGN: Cross‐sectional study…”
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Associations between circulating cell-free mitochondrial DNA, inflammatory markers, and cognitive and physical outcomes in community dwelling older adults by Nidadavolu, Lolita S, Feger, Danielle, Chen, Diefei, Wu, Yuqiong, Grodstein, Francine, Gross, Alden L, Bennett, David A, Walston, Jeremy D, Oh, Esther S, Abadir, Peter M

“…Dementia and frailty are common age-related syndromes often linked to chronic inflammation. Identifying the biological factors and pathways that contribute to…”
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Comorbidity, Frailty, and Waitlist Mortality among Kidney Transplant Candidates of All Ages by Pérez Fernández, María, Martínez Miguel, Patricia, Ying, Hao, Haugen, Christine E, Chu, Nadia M, Rodríguez Puyol, Diego María, Rodríguez-Mañas, Leocadio, Norman, Silas P, Walston, Jeremy D, Segev, Dorry L, McAdams-DeMarco, Mara A

“…Kidney transplantation (KT) candidates often present with multiple comorbidities. These patients also have a substantial burden of frailty, which is also…”
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Sex-Specific Differences in the Effect of Free Testosterone on Sarcopenia Components in Older Adults by Shin, Hyung Eun, Walston, Jeremy D, Kim, Miji, Won, Chang Won

“…The association of free testosterone (FT) with sarcopenia and its components is well known in men but incompletely understood in women. We examined the…”
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Association of fatigue, inflammation, and physical activity on gait speed: the Long Life Family Study by Renner, Sharon W., Qiao, Yujia, Gmelin, Theresa, Santanasto, Adam J., Boudreau, Robert M., Walston, Jeremy D., Perls, Thomas T., Christensen, Kaare, Newman, Anne B., Glynn, Nancy W.

“…Background Fatigue, inflammation, and physical activity (PA) are all independently associated with gait speed, but their directionality is not fully…”
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