Search Results - "Walsmann, P"

Isolation and characterization of hirudin from Hirudo medicinalis by Walsmann, P

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On the isolation of the thrombin inhibitor hirudin by Walsmann, P, Markwardt, F

“…A procedure for isolation of hirudin from crude preparations was described. By the use of ion exchange chromatography and affinity chromatography preparations…”
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Hirudin as a diagnostic agent by Walsmann, P

“…The high specificity and strong affinity of hirudin for thrombin enables the inhibitor to interfere with most effects of this enzyme. The paper reviews the…”
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Isolation and characterization of a thrombin inhibitor from the tick ixodes ricinus by Hoffmann, A, Walsmann, P, Riesener, G, Paintz, M, Markwardt, F

“…The secretion of the salivary glands of ticks, Ixodes ricinus, contains anticoagulant substances. Some years ago an antithromboplastin, ixodin, was described…”
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Cyclic amides of N alpha-arylsulfonylaminoacylated 4-amidinophenylalanine--tight binding inhibitors of thrombin by Stürzebecher, J, Markwardt, F, Voigt, B, Wagner, G, Walsmann, P

“…Variation of the potent thrombin inhibitors derived from N alpha-arylsulfonyl-4-amidinophenylalanine was carried out by interposition of an…”
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Pharmacological studies on the antithrombotic action of hirudin in experimental animals by Markwardt, F, Hauptmann, J, Nowak, G, Klessen, C, Walsmann, P

“…The pharmacodynamics and pharmacokinetics of hirudin were studied in dogs, rabbits and rats. Hirudin proved to be a well tolerated substance with low toxicity…”
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Structure-activity relationships of recombinant hirudins by Stürzebecher, J, Walsmann, P

“…The complex formation between thrombin and hirudin is unique among other serine proteinase-inhibitor complexes. The serpines occupy the specificity pocket of…”
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The hirudin standard by Markwardt, F, Stürzebecher, J, Walsmann, P

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Neutralization of hirudin anticoagulant action by DIP-thrombin by Brüggener, E, Walsmann, P, Markwardt, F

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Inhibition of bovine and human thrombins by derivatives of benzamidine by Stürzebecher, J, Walsmann, P, Voigt, B, Wagner, G

“…Thirty-four derivatives of benzamidine were tested for their inhibitory activities on bovine and human thrombins using the chromogenic peptide substrate…”
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Plasma level of dextran-r-hirudin by Richter, M, Walsmann, P, Markwardt, F

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Inhibition of serine proteinases by benzamidine derivatives by Walsmann, P

“…Derivatives of benzamidine inhibit competitively the activity of the serine proteinases trypsin, plasmin, thrombin, and of the clotting factor Xa. The…”
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A thrombin binding assay for 125I-hirudin by Richter, M, Walsmann, P, Markwardt, F

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Synthetic inhibitors of serine proteinases XIV.+) inhibition of Factor Xa by derivatives of benzamidine by Stürzebecher, J, Markwardt, F, Walsmann, P

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Hirudin binding to soluble dextran by Walsmann, P, Maksimenko, A V, Abramova, V

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Evidence for the identity of hirudin isolated after kidney passage with the starting material by Henschen, A, Markwardt, F, Walsmann, P

“…Natural, sulfated and recombinant, non-sulfated hirudin preparations re-isolated from urine after kidney passage were compared with the corresponding…”
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Synthetic inhibitors of serine proteinases. XXIII. Inhibition of factor Xa by diamidines by Stürzebecher, J, Markwardt, F, Walsmann, P

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Quality control of 125I-labelled fibrinogen of various species by Richter, M, Cyranka, U, Walsmann, P

“…The modified chloramine-T method used for radioiodination of human, rat, and bovine fibrinogen guaranteed mild labelling conditions and a satisfactory…”
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Synthetic inhibitors of serine proteinases. XVI. Influence of 3- and 4-amidinobenzyl derivatives on the formation and action of thrombin by Hauptmann, J, Markwardt, F, Walsmann, P

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Comparative Studies on the Inhibition of Trypsin, Plasmin, and Thrombin by Derivatives of Benzylamine and Benzamidine by Markwardt, F., Landmann, H., Walsmann, P.

“…Derivatives of benzylamine and benzamidine were found to be competitive inhibitors of the proteolytic enzymes trypsin, plasmin, and thrombin. The inhibitor…”
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