Search Results - "Walsh, Sonya"

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  1. 1
    Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

    Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis by Branford, Susan, Rudzki, Zbigniew, Walsh, Sonya, Parkinson, Ian, Grigg, Andrew, Szer, Jeff, Taylor, Kerry, Herrmann, Richard, Seymour, John F., Arthur, Chris, Joske, David, Lynch, Kevin, Hughes, Tim

    Published in Blood (01-07-2003)
    “…Imatinib-treated chronic myeloid leukemia (CML) patients with acquired resistance commonly have detectable BCR-ABL kinase domain mutations. It is unclear…”
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    High frequency of point mutations clustered within the adenosine triphosphate–binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

    High frequency of point mutations clustered within the adenosine triphosphate–binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance by Branford, Susan, Rudzki, Zbigniew, Walsh, Sonya, Grigg, Andrew, Arthur, Chris, Taylor, Kerry, Herrmann, Richard, Lynch, Kevin P., Hughes, Timothy P.

    Published in Blood (01-05-2002)
    “…Point mutations were found in the adenosine triphosphate (ATP) binding region of BCR/ABL in 12 of 18 patients with chronic myeloid leukemia (CML) or…”
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