Search Results - "Walsh, Sharon L"

Therapeutic potential of opioid/cannabinoid combinations in humans: Review of the evidence by Babalonis, Shanna, Walsh, Sharon L.

“…The endogenous opioid and cannabinoid receptor systems are widely distributed and co-localized throughout central and peripheral nervous system regions. A…”
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Cannabinoid Poisoning-Related Emergency Department Visits and Inpatient Hospitalizations in Kentucky, 2017 to 2019 by Britch, Stevie C., Walsh, Sharon L., Vickers-Smith, Rachel, Babalonis, Shanna, Slavova, Svetla

“…Background and objectives: Cannabis is the most used federally illicit substance. Due to widespread medicinal use and state-level legalization, public…”
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Abuse liability and reinforcing efficacy of oral tramadol in humans by Babalonis, Shanna, Lofwall, Michelle R, Nuzzo, Paul A, Siegel, Anthony J, Walsh, Sharon L

“…Abstract Background Tramadol, a monoaminergic reuptake inhibitor, is hepatically metabolized to an opioid agonist (M1). This atypical analgesic is generally…”
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Recent Increase in Methamphetamine Use in a Cohort of Rural People Who Use Drugs: Further Evidence for the Emergence of Twin Epidemics by Havens, Jennifer R, Knudsen, Hannah K, Strickland, Justin C, Young, April M, Babalonis, Shanna, Lofwall, Michelle R, Walsh, Sharon L

“…Appalachian Kentucky was at the epicenter of the prescription opioid epidemic in the early 2000's. As we enter the third decade of the epidemic, patterns have…”
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Bioavailability and Pharmacokinetics of Oral Cocaine in Humans by Coe, Marion A, Jufer Phipps, Rebecca A, Cone, Edward J, Walsh, Sharon L

“…Abstract The pharmacokinetic profile of oral cocaine has not been fully characterized and prospective data on oral bioavailability are limited. A…”
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Scaling up overdose education and naloxone distribution in Kentucky: adoption and reach achieved through a "hub with many spokes" model by Knudsen, Hannah K, Freeman, Patricia R, Oyler, Douglas R, Oser, Carrie B, Walsh, Sharon L

“…Scaling up overdose education and naloxone distribution (OEND), an evidence-based practice for reducing opioid overdose mortality, in communities remains a…”
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Cannabidiol: pharmacology and therapeutic targets by Britch, Stevie C., Babalonis, Shanna, Walsh, Sharon L.

“…Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-treat a myriad of conditions and for their unsubstantiated health…”
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Signal of increased opioid overdose during COVID-19 from emergency medical services data by Slavova, Svetla, Rock, Peter, Bush, Heather M., Quesinberry, Dana, Walsh, Sharon L.

“…•COVID-19 pandemic disrupted treatment service delivery and harm reduction.•Individuals with opioid use disorder may be at heightened risk of opioid…”
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Protocol for community-driven selection of strategies to implement evidence-based practices to reduce opioid overdoses in the HEALing Communities Study: a trial to evaluate a community-engaged intervention in Kentucky, Massachusetts, New York and Ohio by Young, April M, Brown, Jennifer L, Hunt, Timothy, Sprague Martinez, Linda S, Chandler, Redonna, Oga, Emmanuel, Winhusen, T John, Baker, Trevor, Battaglia, Tracy, Bowers-Sword, Rachel, Button, Amy, Fallin-Bennett, Amanda, Fanucchi, Laura, Freeman, Patricia, Glasgow, LaShawn M, Gulley, Jennifer, Kendell, Charles, Lofwall, Michelle, Lyons, Michael S, Quinn, Maria, Rapkin, Bruce David, Surratt, Hilary L, Walsh, Sharon L

“…IntroductionOpioid-involved overdose deaths continue to surge in many communities, despite numerous evidence-based practices (EBPs) that exist to prevent them…”
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Alternatives to dental opioid prescribing after tooth extraction (ADOPT): protocol for a stepped wedge cluster randomized trial by Oyler, Douglas R, Westgate, Philip M, Walsh, Sharon L, Dolly Prothro, Jennifer, Miller, Craig S, Roberts, Monica F, Freeman, Patricia R, Knudsen, Hannah K, Lang, Maggie, Dominguez-Fernandez, Enif, Rojas-Ramirez, Marcia V

“…Dentists and oral surgeons are leading prescribers of opioids to adolescents and young adults (AYA), who are at high risk for developing problematic opioid use…”
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Equity of overdose education and naloxone distribution provided in the Kentucky HEALing Communities Study by Oyler, Douglas R., Knudsen, Hannah K., Oser, Carrie B., Walsh, Sharon L., Roberts, Monica, Nigam, Shawn R., Westgate, Philip M., Freeman, Patricia R.

“…•Strategies to reduce opioid overdose death are not consistently equitably delivered.•Specific strategies to increase naloxone availability for males are…”
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Eliminating hepatitis C in a rural Appalachian county: protocol for the Kentucky Viral Hepatitis Treatment Study (KeY Treat), a phase IV, single-arm, open-label trial of sofosbuvir/velpatasvir for the treatment of hepatitis C by Havens, Jennifer R, Schaninger, Takako, Fraser, Hannah, Lofwall, Michelle, Staton, Michele, Young, April M, Hoven, Ardis, Walsh, Sharon L, Vickerman, Peter

“…ObjectivesThe overall goal of the Kentucky Viral Hepatitis Treatment Study (KeY Treat) is to eliminate hepatitis C transmission from a county in Appalachian…”
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The development of a recovery coaching training curriculum to facilitate linkage to and increase retention on medications for opioid use disorder by Moffitt, Trevor, Fallin-Bennett, Amanda, Fanucchi, Laura, Walsh, Sharon L, Cook, Christopher, Oller, Devin, Ross, Anna, Gallivan, Molly, Lauckner, John, Byard, Jeremy, Wheeler-Crum, Phoebe, Lofwall, Michelle R

“…Medication treatment for opioid use disorder (MOUD) decreases opioid overdose risk and is the standard of care for persons with opioid use disorder (OUD)…”
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Rapid jail-based implementation of overdose education and naloxone distribution in response to the COVID-19 pandemic by Oser, Carrie B., McGladrey, Margaret, Booty, Marisa, Surratt, Hilary, Knudsen, Hannah K., Freeman, Patricia R., Stevens-Watkins, Danelle, Roberts, Monica F., Staton, Michele, Young, April, Draper, Emma, Walsh, Sharon L.

“…Background People incarcerated in jails are highly impacted by the opioid epidemic, and overdose education and naloxone distribution (OEND) is an effective…”
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Gabapentin misuse, abuse and diversion: a systematic review by Smith, Rachel V., Havens, Jennifer R., Walsh, Sharon L.

“…Background and Aims Since its market release, gabapentin has been presumed to have no abuse potential and subsequently has been prescribed widely off‐label,…”
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Efficacy of extended-release tramadol for treatment of prescription opioid withdrawal: A two-phase randomized controlled trial by Lofwall, Michelle R, Babalonis, Shanna, Nuzzo, Paul A, Siegel, Anthony, Campbell, Charles, Walsh, Sharon L

“…Abstract Background Tramadol is an atypical analgesic with monoamine and modest mu opioid agonist activity. The purpose of this study was to evaluate: (1) the…”
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Treatment of opioid overdose: current approaches and recent advances by Britch, Stevie C., Walsh, Sharon L.

“…Background The USA has recently entered the third decade of the opioid epidemic. Opioid overdose deaths reached a new record of over 74,000 in a 12-month…”
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Effects of Short-Term Oxycodone Maintenance on Experimental Pain Responses in Physically Dependent Opioid Abusers by Coe, Marion A, Nuzzo, Paul A, Lofwall, Michelle R, Walsh, Sharon L

“…A common clinical problem with opioid analgesics is the loss of analgesic efficacy after repeated dosing; when this occurs, it is not clear what principles…”
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Pharmacodynamic profile of tramadol in humans: influence of naltrexone pretreatment by Stoops, William W., Lofwall, Michelle R., Nuzzo, Paul A., Craig, Lori B., Siegel, Anthony J., Walsh, Sharon L.

“…Rationale Tramadol is a prescription analgesic that activates mu opioid and monoamine receptor systems. Tramadol is thought to have limited abuse potential…”
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Adaptation of a standard extended-release naltrexone (XR-NTX) protocol for rural re-entering offenders with OUD by Staton, Michele, Knudsen, Hannah K., Walsh, Sharon L., Oser, Carrie, Pike, Erika, Lofwall, Michelle

“…Background Despite a growing body of empirical support for the effectiveness of extended-release naltrexone (XR-NTX) to reduce opioid relapse among people with…”
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