Search Results - "Walsh, Sean"
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Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material
Published in BioTechniques (01-03-2013)“…Procedures utilizing Chelex 100 chelating resin have been developed for extracting DNA from forensic-type samples for use with the PCR. The procedures are…”
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2
U-Net: deep learning for cell counting, detection, and morphometry
Published in Nature methods (01-01-2019)“…U-Net is a generic deep-learning solution for frequently occurring quantification tasks such as cell detection and shape measurements in biomedical image data…”
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Federated learning for multi-center imaging diagnostics: a simulation study in cardiovascular disease
Published in Scientific reports (03-03-2022)“…Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world…”
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Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules
Published in JAMA surgery (01-09-2018)“…Use of next-generation sequencing of RNA and machine learning algorithms can classify the risk of malignancy in cytologically indeterminate thyroid nodules to…”
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Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
Published in The New England journal of medicine (23-08-2012)“…A significant fraction of fine-needle aspirates obtained from thyroid nodules are read as indeterminate. A new molecular test accurately predicts whether a…”
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Radiomics: the bridge between medical imaging and personalized medicine
Published in Nature reviews. Clinical oncology (01-12-2017)“…Key Points Radiomics is becoming increasingly more important in medical imaging The explosion of medical imaging data creates an environment ideal for…”
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Utility of a Molecular Classifier as a Complement to High-Resolution Computed Tomography to Identify Usual Interstitial Pneumonia
Published in American journal of respiratory and critical care medicine (15-01-2021)“…Usual interstitial pneumonia (UIP) is the defining morphology of idiopathic pulmonary fibrosis (IPF). Guidelines for IPF diagnosis conditionally recommend…”
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A Nasal Swab Classifier to Evaluate the Probability of Lung Cancer in Patients With Pulmonary Nodules
Published in Chest (01-04-2024)“…Accurate assessment of the probability of lung cancer (pCA) is critical in patients with pulmonary nodules (PNs) to help guide decision-making. We sought to…”
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A Randomized Trial of Single-Dose Oral Dexamethasone Versus Multidose Prednisolone for Acute Exacerbations of Asthma in Children Who Attend the Emergency Department
Published in Annals of emergency medicine (01-05-2016)“…Study objective In acute exacerbations of asthma in children, corticosteroids reduce relapses, subsequent hospital admission, and the need for ß2 -agonist…”
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Blockchain for Privacy Preserving and Trustworthy Distributed Machine Learning in multicentric Medical Imaging (C-DistriM)
Published in IEEE access (01-01-2020)“…The utility of Artificial Intelligence (AI) in healthcare strongly depends upon the quality of the data used to build models, and the confidence in the…”
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The Anti-Viral Activity of Prunella vulgaris : A Narrative Review
Published in Integrative medicine reports (01-07-2022)“…Introduction: This narrative review reports on the anti-viral activity of Prunella vulgaris with the aim of providing an overview of P. vulgaris research to…”
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Systems‐based analysis of Arabidopsis leaf growth reveals adaptation to water deficit
Published in Molecular systems biology (2012)“…Leaves have a central role in plant energy capture and carbon conversion and therefore must continuously adapt their development to prevailing environmental…”
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Analytical and Clinical Validation of Expressed Variants and Fusions From the Whole Transcriptome of Thyroid FNA Samples
Published in Frontiers in endocrinology (Lausanne) (11-09-2019)“…Introduction: The Afirma® Xpression Atlas (XA) detects gene variants and fusions in thyroid nodule FNA samples from a curated panel of 511 genes using…”
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External validation of a radiomic signature to predict p16 (HPV) status from standard CT images of anal cancer patients
Published in Scientific reports (03-05-2023)“…The paper deals with the evaluation of the performance of an existing and previously validated CT based radiomic signature, developed in oropharyngeal cancer…”
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Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions
Published in BMC genomics (09-05-2018)“…We developed a classifier using RNA sequencing data that identifies the usual interstitial pneumonia (UIP) pattern for the diagnosis of idiopathic pulmonary…”
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Analytical validation of the Percepta genomic sequencing classifier; an RNA next generation sequencing assay for the assessment of Lung Cancer risk of suspicious pulmonary nodules
Published in BMC cancer (13-04-2021)“…Bronchoscopy is a common procedure used for evaluation of suspicious lung nodules, but the low diagnostic sensitivity of bronchoscopy often results in…”
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Benefit of particle therapy in re-irradiation of head and neck patients. Results of a multicentric in silico ROCOCO trial
Published in Radiotherapy and oncology (01-12-2016)“…Abstract Background and Purpose In this multicentric in silico trial we compared photon, proton, and carbon-ion radiotherapy plans for re-irradiation of…”
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Big Data in radiation therapy: challenges and opportunities
Published in British journal of radiology (01-01-2017)“…Data collected and generated by radiation oncology can be classified by the Volume, Variety, Velocity and Veracity (4Vs) of Big Data because they are spread…”
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Editorial: Imaging assessment of response to immunotherapy
Published in Frontiers in oncology (20-01-2023)Get full text
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Parallel analysis of Arabidopsis circadian clock mutants reveals different scales of transcriptome and proteome regulation
Published in Open biology (01-03-2017)“…The circadian clock regulates physiological processes central to growth and survival. To date, most plant circadian clock studies have relied on diurnal…”
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