Search Results - "Walsh, Katy R."
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Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer’s disease
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2022)“…The brain microcirculation is increasingly viewed as a potential target for disease-modifying drugs in the treatment of Alzheimer’s disease patients,…”
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Uncoupling of Ca2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-2023)“…There are no treatments available for vascular dementia, the second-most common dementia syndrome, and patients decline rapidly after diagnosis. This syndrome…”
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Uncoupling of Ca 2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-2023)“…The deficit in cerebral blood flow (CBF) seen in patients with hypertension-induced vascular dementia is increasingly viewed as a therapeutic target for…”
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PS-B10-7: A VASCULAR SMOOTH MUSCLE POTASSIUM CHANNEL DYSFUNCTION UNDERLIES SMALL VESSEL DISEASE OF THE BRAIN IN BOTH HYPERTENSION AND ALZHEIMER'S DISEASE
Published in Journal of hypertension (01-01-2023)“…Alzheimer's disease (AD) and hypertension-related vascular dementia share many common clinical and radiological features. Indeed, at post-mortem the majority…”
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