Search Results - "Walsh, Jonathon D"

Tracking N- and C-termini of C. elegans polycystin-1 reveals their distinct targeting requirements and functions in cilia and extracellular vesicles by Walsh, Jonathon D, Wang, Juan, DeHart, Molly, Nikonorova, Inna A, Srinivasan, Jagan, Barr, Maureen M

“…The cilium acts as an antenna receiving and sending signals, the latter via extracellular vesicles (EVs). In C. elegans and mammals, the Autosomal Dominant…”
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IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium by Wingfield, Jenna L, Mengoni, Ilaria, Bomberger, Heather, Jiang, Yu-Yang, Walsh, Jonathon D, Brown, Jason M, Picariello, Tyler, Cochran, Deborah A, Zhu, Bing, Pan, Junmin, Eggenschwiler, Jonathan, Gaertig, Jacek, Witman, George B, Kner, Peter, Lechtreck, Karl

“…Intraflagellar transport (IFT) trains, multimegadalton assemblies of IFT proteins and motors, traffic proteins in cilia. To study how trains assemble, we…”
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Mutation of NEKL-4/NEK10 and TTLL genes suppress neuronal ciliary degeneration caused by loss of CCPP-1 deglutamylase function by Power, Kade M, Akella, Jyothi S, Gu, Amanda, Walsh, Jonathon D, Bellotti, Sebastian, Morash, Margaret, Zhang, Winnie, Ramadan, Yasmin H, Ross, Nicole, Golden, Andy, Smith, Harold E, Barr, Maureen M, O'Hagan, Robert

“…Ciliary microtubules are subject to post-translational modifications that act as a "Tubulin Code" to regulate motor traffic, binding proteins and stability. In…”
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Sensory cilia act as a specialized venue for regulated extracellular vesicle biogenesis and signaling by Wang, Juan, Nikonorova, Inna A., Silva, Malan, Walsh, Jonathon D., Tilton, Peter E., Gu, Amanda, Akella, Jyothi S., Barr, Maureen M.

“…Ciliary extracellular vesicle (EV) shedding is evolutionarily conserved. In Chlamydomonas and C. elegans, ciliary EVs act as signaling devices.1–3 In cultured…”
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Isolation, profiling, and tracking of extracellular vesicle cargo in Caenorhabditis elegans by Nikonorova, Inna A., Wang, Juan, Cope, Alexander L., Tilton, Peter E., Power, Kaiden M., Walsh, Jonathon D., Akella, Jyothi S., Krauchunas, Amber R., Shah, Premal, Barr, Maureen M.

“…Extracellular vesicles (EVs) may mediate intercellular communication by carrying protein and RNA cargo. The composition, biology, and roles of EVs in…”
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What about the males? the C. elegans sexually dimorphic nervous system and a CRISPR-based tool to study males in a hermaphroditic species by Walsh, Jonathon D., Boivin, Olivier, Barr, Maureen M.

“…Sexual dimorphism is a device that supports genetic diversity while providing selective pressure against speciation. This phenomenon is at the core of sexually…”
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