Search Results - "Walsh, David A."

Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis by Mapp, Paul I., Walsh, David A.

“…Angiogenesis facilitates inflammation and contributes to structural disease progression in osteoarthritis (OA). As new blood vessel growth is coupled with…”
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Quantitative sensory testing and predicting outcomes for musculoskeletal pain, disability, and negative affect: a systematic review and meta-analysis by Georgopoulos, Vasileios, Akin-Akinyosoye, Kehinde, Zhang, Weiya, McWilliams, Daniel F., Hendrick, Paul, Walsh, David A.

“…Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse clinical outcomes, but the ability of quantitative sensory testing…”
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Giant virus diversity and host interactions through global metagenomics by Schulz, Frederik, Roux, Simon, Paez-Espino, David, Jungbluth, Sean, Walsh, David A., Denef, Vincent J., McMahon, Katherine D., Konstantinidis, Konstantinos T., Eloe-Fadrosh, Emiley A., Kyrpides, Nikos C., Woyke, Tanja

“…Our current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely derived from viral isolates that are co-cultivated with protists and algae…”
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Mechanisms, impact and management of pain in rheumatoid arthritis by Walsh, David A., McWilliams, Daniel F.

“…Key Points Pain in rheumatoid arthritis (RA) results from interplay between joint pathology and processing of pain signals by peripheral nerves, spinal and…”
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Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages by Kieft, Kristopher, Zhou, Zhichao, Anderson, Rika E., Buchan, Alison, Campbell, Barbara J., Hallam, Steven J., Hess, Matthias, Sullivan, Matthew B., Walsh, David A., Roux, Simon, Anantharaman, Karthik

“…Microbial sulfur metabolism contributes to biogeochemical cycling on global scales. Sulfur metabolizing microbes are infected by phages that can encode…”
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Association of subchondral bone marrow lesion localization with weight-bearing pain in people with knee osteoarthritis: data from the Osteoarthritis Initiative by Aso, Koji, Shahtaheri, Seyed Mohsen, McWilliams, Daniel F, Walsh, David A

“…Subchondral bone marrow lesions (BMLs) detected on MRI in knee osteoarthritis (OA) are associated with knee pain. The prevalence and progression of subchondral…”
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Television and Video Game Exposure and the Development of Attention Problems by SWING, Edward L, GENTILE, Douglas A, ANDERSON, Craig A, WALSH, David A

“…Television viewing has been associated with greater subsequent attention problems in children. Few studies have examined the possibility of a similar…”
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Calcitonin gene‐related peptide in the joint: contributions to pain and inflammation by Walsh, David A., Mapp, Paul I., Kelly, Sara

“…Arthritis is the commonest cause of disabling chronic pain, and both osteoarthritis (OA) and rheumatoid arthritis (RA) remain major burdens on both individuals…”
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Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis by Ashraf, Sadaf, Mapp, Paul I., Walsh, David A.

“…Objective To determine the contributions of angiogenesis to inflammation, joint damage, and pain behavior in a rat meniscal transection model of osteoarthritis…”
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Diversity and biogeography of SAR11 bacteria from the Arctic Ocean by Kraemer, Susanne, Ramachandran, Arthi, Colatriano, David, Lovejoy, Connie, Walsh, David A.

“…The Arctic Ocean is relatively isolated from other oceans and consists of strongly stratified water masses with distinct histories, nutrient, temperature, and…”
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A Novel Freshwater to Marine Evolutionary Transition Revealed within Methylophilaceae Bacteria from the Arctic Ocean by Ramachandran, Arthi, McLatchie, Susan, Walsh, David A

“…Bacteria inhabiting polar oceans, particularly the Arctic Ocean, are less studied than those at lower latitudes. Discovering bacterial adaptations to Arctic…”
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Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis Cartilage by Pearson, Mark J., Philp, Ashleigh M., Heward, James A., Roux, Benoit T., Walsh, David A., Davis, Edward T., Lindsay, Mark A., Jones, Simon W.

“…Objective To identify long noncoding RNAs (lncRNAs), including long intergenic noncoding RNAs (lincRNAs), antisense RNAs, and pseudogenes, associated with the…”
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Annual nitrification dynamics in a seasonally ice-covered lake by Massé, Stéphanie, Botrel, Morgan, Walsh, David A, Maranger, Roxane

“…We investigated the variability in ammonia oxidation (AO) rates and the presence of ammonia-oxidizing archaea and bacteria (AOB and AOA) over an annual cycle…”
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Structural Associations of Symptomatic Knee Osteoarthritis by Stoppiello, Laura A., Mapp, Paul I., Wilson, Deborah, Hill, Roger, Scammell, Brigitte E., Walsh, David A.

“…Objective Structural changes of osteoarthritis (OA) may occur in the absence of pain. In this study, we aimed to identify histopathologic features that are…”
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Long‐Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial by Hochberg, Marc C., Carrino, John A., Schnitzer, Thomas J., Guermazi, Ali, Walsh, David A., White, Alexander, Nakajo, Satoru, Fountaine, Robert J., Hickman, Anne, Pixton, Glenn, Viktrup, Lars, Brown, Mark T., West, Christine R., Verburg, Kenneth M.

“…Objective To assess the long‐term safety and 16‐week efficacy of subcutaneous tanezumab in patients with hip or knee osteoarthritis (OA). Methods This was a…”
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The NSERC Canadian Lake Pulse Network: A national assessment of lake health providing science for water management in a changing climate by Huot, Yannick, Brown, Catherine A., Potvin, Geneviève, Antoniades, Dermot, Baulch, Helen M., Beisner, Beatrix E., Bélanger, Simon, Brazeau, Stéphanie, Cabana, Hubert, Cardille, Jeffrey A., del Giorgio, Paul A., Gregory-Eaves, Irene, Fortin, Marie-Josée, Lang, Andrew S., Laurion, Isabelle, Maranger, Roxane, Prairie, Yves T., Rusak, James A., Segura, Pedro A., Siron, Robert, Smol, John P., Vinebrooke, Rolf D., Walsh, David A.

“…The distribution and quality of water resources vary dramatically across Canada, and human impacts such as land-use and climate changes are exacerbating…”
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Toward a comprehensive taxonomy of human motives by Talevich, Jennifer R, Read, Stephen J, Walsh, David A, Iyer, Ravi, Chopra, Gurveen

“…A major success in personality has been the development of a consensual structure of traits. However, much less progress has been made on the structure of an…”
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Hand and Foot Surgery Rates in Rheumatoid Arthritis Have Declined From 1986 to 2011, but Large‐Joint Replacement Rates Remain Unchanged: Results From Two UK Inception Cohorts by Nikiphorou, Elena, Carpenter, Lewis, Morris, Stephen, MacGregor, Alex J., Dixey, Josh, Kiely, Patrick, James, David W., Walsh, David A., Norton, Sam, Young, Adam

“…Objective To assess whether there have been any secular changes in orthopedic interventions in patients with rheumatoid arthritis (RA) since 1986, as examined…”
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Degradation pathways for organic matter of terrestrial origin are widespread and expressed in Arctic Ocean microbiomes by Grevesse, Thomas, Guéguen, Céline, Onana, Vera E, Walsh, David A

“…The Arctic Ocean receives massive freshwater input and a correspondingly large amount of humic-rich organic matter of terrestrial origin. Global warming,…”
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Contribution of inflammation markers and quantitative sensory testing (QST) indices of central sensitisation to rheumatoid arthritis pain by Georgopoulos, Vasileios, Smith, Stephanie, McWilliams, Daniel F, Ferguson, Eamonn, Wakefield, Richard, Platts, Dorothy, Ledbury, Susanne, Wilson, Deborah, Walsh, David A

“…Pain, the primary complaint in rheumatoid arthritis (RA), is multifaceted, and may be driven by inflammatory disease activity and central sensitisation. We…”
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