Search Results - "Walpole, Samuel"

Dynamic and Principled: The Influence of Sir Anthony Mason by Samuel Walpole

“…Review(s) of: Dynamic and principled: The influence of Sir Anthony Mason, Barbara McDonald, Ben Chen and Jeffrey, Gordon (eds); Federation Press, 2022; 464,…”
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Fighting the system: New approaches to addressing systematic corporate misconduct by Walpole, Samuel, Corrigan, Matt

“…Traditional criminal law evolved to address morally unacceptable conduct by individuals, before expanding into regulatory contexts. Classical models of…”
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Structural basis for arginine glycosylation of host substrates by bacterial effector proteins by Park, Jun Bae, Kim, Young Hun, Yoo, Youngki, Kim, Juyeon, Jun, Sung-Hoon, Cho, Jin Won, El Qaidi, Samir, Walpole, Samuel, Monaco, Serena, García-García, Ana A., Wu, Miaomiao, Hays, Michael P., Hurtado-Guerrero, Ramon, Angulo, Jesus, Hardwidge, Philip R., Shin, Jeon-Soo, Cho, Hyun-Soo

“…The bacterial effector proteins SseK and NleB glycosylate host proteins on arginine residues, leading to reduced NF-κB-dependent responses to infection…”
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Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design by Beekman, Andrew M, Cominetti, Marco M D, Walpole, Samuel J, Prabhu, Saurabh, O'Connell, Maria A, Angulo, Jesus, Searcey, Mark

“…The development of protein-protein interaction (PPI) inhibitors with therapeutic value is of increasing importance as the first clinical agent has now been…”
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The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract by Wu, Haiyang, Crost, Emmanuelle H, Owen, C David, van Bakel, Wouter, Martínez Gascueña, Ana, Latousakis, Dimitrios, Hicks, Thomas, Walpole, Samuel, Urbanowicz, Paulina A, Ndeh, Didier, Monaco, Serena, Sánchez Salom, Laura, Griffiths, Ryan, Reynolds, Raven S, Colvile, Anna, Spencer, Daniel I R, Walsh, Martin, Angulo, Jesus, Juge, Nathalie

“…The human gut symbiont Ruminococcus gnavus displays strain-specific repertoires of glycoside hydrolases (GHs) contributing to its spatial location in the gut…”
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The intrinsically disordered Tarp protein from chlamydia binds actin with a partially preformed helix by Tolchard, James, Walpole, Samuel J., Miles, Andrew J., Maytum, Robin, Eaglen, Lawrence A., Hackstadt, Ted, Wallace, B. A., Blumenschein, Tharin M. A.

“…Tarp (translocated actin recruiting phosphoprotein) is an effector protein common to all chlamydial species that functions to remodel the host-actin…”
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Correction: Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design by Beekman, Andrew M., Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O’Connell, Maria A., Angulo, Jesus, Searcey, Mark

“…Correction for ‘Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design’ by Andrew M…”
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Hotchpot and the insolvent trading trustee: Commissioner of Taxation v Lane [2020] FCAFC 184 by Walpole, Samuel

“…Abstract For forty years, the insolvency of trading trustees in Australia has produced uncertainty. In 2019, the High Court of Australia resolved the central…”
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Fighting the system: New approaches to addressing systematic corporate misconduct by Samuel Walpole, Matt Corrigan

“…Traditional criminal law evolved to address morally unacceptable conduct by individuals, before expanding into regulatory contexts. Classical models of…”
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Fighting the system: New approaches to addressing systematic corporate misconduct by Samuel Walpole, Matt Corrigan

“…Traditional criminal law evolved to address morally unacceptable conduct by individuals, before expanding into regulatory contexts. Classical models of…”
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Bug Off Pain: An Educational Virtual Reality Game on Spider Venoms and Chronic Pain for Public Engagement by Bibic, Lucka, Druskis, Justinas, Walpole, Samuel, Angulo, Jesus, Stokes, Leanne

“…Virtual reality (VR) technology has been capturing the public imagination for decades. VR software applications that allow for interactive immersion are…”
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Deriving Ligand Orientation in Weak Protein–Ligand Complexes by DEEP‐STD NMR Spectroscopy in the Absence of Protein Chemical‐Shift Assignment by Nepravishta, Ridvan, Walpole, Samuel, Tailford, Louise, Juge, Nathalie, Angulo, Jesus

“…Differential epitope mapping saturation transfer difference (DEEP‐STD) NMR spectroscopy is a recently developed powerful approach for elucidating the structure…”
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Fast Quantitative Validation of 3D Models of Low-Affinity Protein–Ligand Complexes by STD NMR Spectroscopy by Nepravishta, Ridvan, Ramírez-Cárdenas, Jonathan, Rocha, Gabriel, Walpole, Samuel, Hicks, Thomas, Monaco, Serena, Muñoz-García, Juan C., Angulo, Jesús

“…Low-affinity protein–ligand interactions are important for many biological processes, including cell communication, signal transduction, and immune responses…”
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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 by Bidula, Stefan M., Cromer, Brett A., Walpole, Samuel, Angulo, Jesus, Stokes, Leanne

“…P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and…”
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Fucosidases from the human gut symbiont Ruminococcus gnavus by Wu, Haiyang, Rebello, Osmond, Crost, Emmanuelle H., Owen, C. David, Walpole, Samuel, Bennati-Granier, Chloe, Ndeh, Didier, Monaco, Serena, Hicks, Thomas, Colvile, Anna, Urbanowicz, Paulina A., Walsh, Martin A., Angulo, Jesus, Spencer, Daniel I. R., Juge, Nathalie

“…The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation of gut bacteria species to ecological…”
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Ginsenosides Act As Positive Modulators of P2X4 Receptors by Dhuna, Kshitija, Felgate, Matthew, Bidula, Stefan M, Walpole, Samuel, Bibic, Lucka, Cromer, Brett A, Angulo, Jesus, Sanderson, Julie, Stebbing, Martin J, Stokes, Leanne

“…We investigated the selectivity of protopanaxadiol ginsenosides from acting as positive allosteric modulators on P2X receptors. ATP-induced responses were…”
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Structural basis for the role of serine-rich repeat proteins from Lactobacillus reuteri in gut microbe–host interactions by Sequeira, Saannya, Kavanaugh, Devon, MacKenzie, Donald A., Šuligoj, Tanja, Walpole, Samuel, Leclaire, Charlotte, Gunning, A. Patrick, Latousakis, Dimitrios, Willats, William G. T., Angulo, Jesus, Dong, Changjiang, Juge, Nathalie

“…Lactobacillus reuteri, a Gram-positive bacterial species inhabiting the gastrointestinal tract of vertebrates, displays remarkable host adaptation. Previous…”
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Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors by Watt, Jessica E., Hughes, Gregory R., Walpole, Samuel, Monaco, Serena, Stephenson, G. Richard, Bulman Page, Philip C., Hemmings, Andrew M., Angulo, Jesus, Chantry, Andrew

“…We have screened small molecule libraries specifically for inhibitors that target WWP2, an E3 ubiquitin ligase associated with tumour outgrowth and spread…”
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Speeding-up the Determination of Protein–Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR) by Rocha, Gabriel, Ramírez-Cárdenas, Jonathan, Padilla-Pérez, M. Carmen, Walpole, Samuel, Nepravishta, Ridvan, García-Moreno, M. Isabel, Sánchez-Fernández, Elena M., Ortiz Mellet, Carmen, Angulo, Jesús, Muñoz-García, Juan C.

“…STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small molecules and low molecular weight…”
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Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand designElectronic supplementary information (ESI) available: Experimental procedures, spectra and processed biophysical assay data. See DOI: 10.1039/c9sc00059c by Beekman, Andrew M, Cominetti, Marco M. D, Walpole, Samuel J, Prabhu, Saurabh, O'Connell, Maria A, Angulo, Jesus, Searcey, Mark

“…The development of protein-protein interaction (PPI) inhibitors with therapeutic value is of increasing importance as the first clinical agent has now been…”
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