Search Results - "Walmsley, S"

Refeeding syndrome: Screening, incidence, and treatment during parenteral nutrition by Walmsley, Russell S

“…The possible deleterious effects of feeding after a period of prolonged starvation have been known for over 60 years. The resultant biochemical disturbance,…”
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Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer by Coates, James T, Sun, Sheng, Leshchiner, Ignaty, Thimmiah, Nayana, Martin, Elizabeth E, McLoughlin, Daniel, Danysh, Brian P, Slowik, Kara, Jacobs, Raquel A, Rhrissorrakrai, Kahn, Utro, Filippo, Levovitz, Chaya, Denault, Elyssa, Walmsley, Charlotte S, Kambadakone, Avinash, Stone, James R, Isakoff, Steven J, Parida, Laxmi, Juric, Dejan, Getz, Gad, Bardia, Aditya, Ellisen, Leif W

“…Sacituzumab govitecan (SG), the first antibody-drug conjugate (ADC) approved for triple-negative breast cancer, incorporates the anti-TROP2 antibody hRS7…”
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α by Tannahill, G. M., Curtis, A. M., Adamik, J., Palsson-McDermott, E. M., McGettrick, A. F., Goel, G., Frezza, C., Bernard, N. J., Kelly, B., Foley, N. H., Zheng, L., Gardet, A., Tong, Z., Jany, S. S., Corr, S. C., Haneklaus, M., Caffrey, B. E., Pierce, K., Walmsley, S., Beasley, F. C., Cummins, E., Nizet, V., Whyte, M., Taylor, C. T., Lin, H., Masters, S. L., Gottlieb, E., Kelly, V. P., Clish, C., Auron, P. E., Xavier, R. J., O’Neill, L. A. J.

“…Succinate is identified as a metabolite in innate immune signalling, which leads to enhanced interleukin-1β production during inflammation. Succinate is an…”
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Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers by Klotz, Remi, Thomas, Amal, Teng, Teng, Han, Sung Min, Iriondo, Oihana, Li, Lin, Restrepo-Vassalli, Sara, Wang, Alan, Izadian, Negeen, MacKay, Matthew, Moon, Byoung-San, Liu, Kevin J, Ganesan, Sathish Kumar, Lee, Grace, Kang, Diane S, Walmsley, Charlotte S, Pinto, Christopher, Press, Michael F, Lu, Wange, Lu, Janice, Juric, Dejan, Bardia, Aditya, Hicks, James, Salhia, Bodour, Attenello, Frank, Smith, Andrew D, Yu, Min

“…Hematogenous metastasis is initiated by a subset of circulating tumor cells (CTC) shed from primary or metastatic tumors into the blood circulation. Thus, CTCs…”
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The VEGF receptor neuropilin 2 promotes homologous recombination by stimulating YAP/TAZ-mediated Rad51 expression by Elaimy, Ameer L., Amante, John J., Zhu, Lihua Julie, Wang, Mengdie, Walmsley, Charlotte S., FitzGerald, Thomas J., Goel, Hira Lal, Mercurio, Arthur M.

“…Vascular endothelial growth factor (VEGF) signaling in tumor cells mediated by neuropilins (NRPs) contributes to the aggressive nature of several cancers,…”
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EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma by Wu, Qibiao, Zhen, Yuanli, Shi, Lei, Vu, Phuong, Greninger, Patricia, Adil, Ramzi, Merritt, Joshua, Egan, Regina, Wu, Meng-Ju, Yin, Xunqin, Ferrone, Cristina R, Deshpande, Vikram, Baiev, Islam, Pinto, Christopher J, McLoughlin, Daniel E, Walmsley, Charlotte S, Stone, James R, Gordan, John D, Zhu, Andrew X, Juric, Dejan, Goyal, Lipika, Benes, Cyril H, Bardeesy, Nabeel

“…FGFR inhibitors are approved for the treatment of advanced cholangiocarcinoma harboring FGFR2 fusions. However, the response rate is moderate, and resistance…”
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Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages by Bain, C C, Gibson, D A, Steers, N J, Boufea, K, Louwe, P A, Doherty, C, González-Huici, V, Gentek, R, Magalhaes-Pinto, M, Shaw, T, Bajénoff, M, Bénézech, C, Walmsley, S R, Dockrell, D H, Saunders, P T K, Batada, N N, Jenkins, S J

“…Macrophages reside in the body cavities where they maintain serosal homeostasis and provide immune surveillance. Peritoneal macrophages are implicated in the…”
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Color inference in visual communication: the meaning of colors in recycling by Schloss, Karen B., Lessard, Laurent, Walmsley, Charlotte S., Foley, Kathleen

“…People interpret abstract meanings from colors, which makes color a useful perceptual feature for visual communication. This process is complicated, however,…”
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Successful treatment of parenteral nutrition–associated liver disease in an adult by use of a fish oil–based lipid source by Venecourt-Jackson, Esra, B.H.B., M.B.Ch.B, Hill, Simon J., BSc (Pharm), DipClinPharm, Walmsley, Russell S., M.D., F.R.C.P., F.R.A.C.P

“…Abstract Liver disease occurs in 15% to 40% of adults on long-term parenteral nutrition, with steatosis being more common than cholestasis in the adult…”
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Immunological and virological response to initial antiretroviral therapy among older people living with HIV in the Canadian Observational Cohort (CANOC) by Zhabokritsky, A, Szadkowski, L, Burchell, AN, Cooper, C, Hogg, RS, Hull, M, Kelly, DV, Klein, M, Loutfy, M, McClean, A, Montaner, J, Walmsley, SL

“…Objectives The aim of this study was to assess the adequacy of immunological recovery and virological suppression in response to antiretroviral therapy (ART)…”
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Perspectives on strategies for improving ultra-deep desulfurization of liquid fuels through hydrotreatment: Catalyst improvement and feedstock pre-treatment by Dembaremba, Tendai O., Majodina, Siphumelele, Walmsley, Ryan S., Ogunlaja, Adeniyi S., Tshentu, Zenixole R.

“…Reliance on crude oil remains high while the transition to green and renewable sources of fuel is still slow. Developing and strengthening strategies for…”
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A simple clinical colitis activity index by Walmsley, R S, Ayres, R C S, Pounder, R E, Allan, R N

“…Background—The appropriate medical treatment of patients with ulcerative colitis is determined largely by the severity of symptoms. Hospital assessment of the…”
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Contraceptive options for HIV‐positive women: making evidence‐based, patient‐centred decisions by Sharma, M, Walmsley, SL

“…Objectives Women of reproductive age represent a large proportion of the global population living with HIV/AIDS. With improvements in morbidity and mortality…”
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Loneliness and perceived social support in pregnancy and early postpartum of mothers living with HIV in Ontario, Canada by Khan, S., Ion, A., Alyass, A., Greene, S., Kwaramba, G., Smith, S., Carvalhal, A., Kennedy, V.L., Walmsley, S., Loutfy, M.

“…The HIV Mothering Study (n = 72) was a prospective, observational, cohort study exploring psychosocial experiences and needs of WLWHIV in pregnancy and…”
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Temporal lower limb barriers and facilitators to participation in targeted lifestyle programs for people with morbid obesity by Penkala, S, Chowdhury, A, Walmsley, S

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Fragility fractures and bone mineral density in HIV positive women : a case-control population-based study by PRIOR, J, BURDGE, D, MAAN, E, MILNER, R, HANKINS, C, KLEIN, M, WALMSLEY, S

“…This Canadian study of bone health showed that HIV+ women were more likely to have had fragility fractures (OR 1.7) but had BMD values that were not different…”
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An Initial Evaluation of Human Plasma cMLC-1: A Potential Protein Biomarker for Trastuzumab-Induced Cardiotoxicity, Breast Cancer Screening and Progression by Yu, Ling, Allen, Read, Jia, Lin, Sun, Ting, Isakoff, Steven J, Scherrer-Crosbie, Marielle, Kehlmann, Allison M, Zheng, Hui, Ly, Amy, Walmsley, Charlotte S, Hesler, Katherine, Varasteh, Ava N, Pinto, Christopher J, McLoughlin, Daniel E, Wu, Wenjin, Wang, Xinhui

“…Trastuzumab is a targeted therapy for human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, trastuzumab-induced cardiotoxicity (TIC)…”
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Infliximab or cyclosporine for acute severe ulcerative colitis: A retrospective analysis by Dean, Kathryn E, Hikaka, Joanna, Huakau, John T, Walmsley, Russell S

“…Background and Aim:  Medical treatment of steroid‐refractory ulcerative colitis (UC) is limited to either cyclosporine or infliximab. Studies comparing…”
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Switch to raltegravir decreases soluble CD14 in virologically suppressed overweight women: the Women, Integrase and Fat Accumulation Trial by Lake, JE, McComsey, GA, Hulgan, T, Wanke, CA, Mangili, A, Walmsley, SL, Stramotas, SA, Tracy, R, Currier, JS

“…Objectives Soluble CD14 (sCD14) is a monocyte activation marker associated with increased mortality in HIV infection. We assessed 48‐week changes in sCD14 and…”
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2: Cervical dysplasia and associated HPV types in a cohort of HIV-positive women by McClymont, E, Lee, M, Moses, E, Blitz, S, Coutlée, F, Walmsley, S, Lipsky, N, Money, D.M

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