Search Results - "Walls, Jenna D"

Characterization and Novel Purification of Recombinant Human Protein C from Three Mammalian Cell Lines by Yan, S.C. Betty, Razzano, Pam, Chao, Y. Bernice, Walls, Jenna D, Berg, David T, McClure, Don B, Grinnell, Brain W

“…Human Protein C (HPC), an antithrombotic factor with potential clinical utility, is a vitamin K-dependent protein that has several complex post-translational…”
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The purification and characterization of recombinant human renin expressed in the human kidney cell line 293 by Vlahos, C J, Walls, J D, Berg, D T, Grinnell, B W

“…The cDNA encoding human preprorenin has been introduced into the adenovirus-transformed human kidney cell line 293. The recombinant 293 cells expressed and…”
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Glycosylation of human protein C affects its secretion, processing, functional activities, and activation by thrombin by GRINNELL, B. W, WALLS, J. D, GERLITZ, B

“…Human protein C (HPC) is an antithrombotic serine protease that circulates in the plasma as several glycoforms. To examine the role of glycosylation in the…”
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Post-translational processing events in the secretion pathway of human protein C, a complex vitamin K-dependent antithrombotic factor by MCCLURE, D. B, WALLS, J. D, GRINNELL, B. W

“…Human protein C (HPC) undergoes several post-translational modifications, including gamma-carboxylation, N-linked glycosylation, and internal proteolytic…”
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γ-Carboxylated Isoforms of Recombinant Human Protein S With Different Biologic Properties by Grinnell, Brian W., Walls, Jenna D., Marks, Carol, Glasebrook, Andrew L., Berg, David T., Yan, S. Betty, Bang, Nils U.

“…Human protein S (HPS), a regulator of hemostasis, is a vitamin K-dependent plasma protein with potential clinical utility. We have obtained high-level…”
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Amplification of multicistronic plasmids in the human 293 cell line and secretion of correctly processed recombinant human protein C by Walls, J D, Berg, D T, Yan, S B, Grinnell, B W

“…We have constructed multicistronic vectors containing the cDNAs for murine dihydrofolate reductase (DHFR), hygromycin phosphotransferase (HyPR), and human…”
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Characterization of a modified human tissue plasminogen activator comprising a kringle-2 and a protease domain by BURCK, P. J, BERG, D. H, GRINNELL, B. W, WARRICK, M. W, BERG, D. T, WALLS, J. D, JASKUNAS, S. R, CRISEL, R. M, WEIGEL, B, VLAHOS, C. J, MCCLURE, D. B

“…To study structure/function relationships of tissue plasminogen activator (t-PA) activity, one of the simplest modified t-PA structures to activate plasminogen…”
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A variant enhancer/regulatory region from a cloned human prototype BK virus genome by BERG, D. T, WALLS, J. D, GRINNELL, B. W

“…The authors have cloned the genome of a unique human BK virus strain, designated BKV-P2, from a preparation of prototype (Gardner) BK virus grown in human…”
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Negative Regulation of the Human Polyomavirus BK Enhancer Involves Cell-Specific Interaction with a Nuclear Repressor by Grinnell, Brian W., Berg, David T., Walls, Jenna D.

“…We have examined the cell type-specific regulation of the human BK virus (BKV) enhancer. This enhancer functions efficiently in cis to activate expression from…”
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Viral transformation increases vitamin K-dependent gamma-carboxylation of glutamate by Berg, D T, McClure, D B, Walls, J D, Yan, S B, Grinnell, B W

“…Mammalian cells contain a microsomal vitamin K-dependent carboxylase activity which catalyzes the gamma-carboxylation of glutamate. While most cells have a…”
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E1A-Induced Enhancer Activity of the Poly(dG-dT) · Poly(dA-dC) Element (GT Element) and Interactions with a GT-Specific Nuclear Factor by Berg, David T., Walls, Jenna D., Reifel-Miller, Anne E., Grinnell, Brian W.

“…The alternating sequence poly(dG-dT) · poly(dA-dC) is a highly repeated sequence in the eucaryotic genome. We have examined the effect of trans-acting early…”
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