Search Results - "Wallich, R"

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin by Pardo, J, Wallich, R, Ebnet, K, Iden, S, Zentgraf, H, Martin, P, Ekiciler, A, Prins, A, Müllbacher, A, Huber, M, Simon, M M

“…Mast cells respond to pathogens and allergens by secreting a vast array of preformed and newly synthesized mediators, including enzymes, vasoactive amines,…”
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Mouse granzyme K has pro-inflammatory potential by Joeckel, L T, Wallich, R, Martin, P, Sanchez-Martinez, D, Weber, F C, Martin, S F, Borner, C, Pardo, J, Froelich, C, Simon, M M

“…Granzymes (gzms) are key components of T-killer (Tc) cells believed to mediate pro-apoptotic activities. Recent evidence suggests that gzms also possess…”
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Granzyme B-induced cell death exerted by ex vivo CTL: discriminating requirements for cell death and some of its signs by Pardo, J, Wallich, R, Martin, P, Urban, C, Rongvaux, A, Flavell, R A, Müllbacher, A, Borner, C, Simon, M M

“…Granzyme B (gzmB) of cytotoxic T lymphocytes (CTL) is essential for recovery from intracellular pathogens, but the molecular basis of its action is still…”
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Molecular cloning and immunological characterization of a novel linear-plasmid-encoded gene, pG, of Borrelia burgdorferi expressed only in vivo by Wallich, R. (German Cancer Research Center, Heidelberg, Germany.), Brenner, C, Kramer, M.D, Simon, M.M

“…Previously we have found that sera from immunocompetent mice infected either naturally by ticks or experimentally with low numbers of Borrelia burgdorferi ZS7…”
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Concerted Action of the FasL/Fas and Perforin/Granzyme A and B Pathways Is Mandatory for the Development of Early Viral Hepatitis but Not for Recovery from Viral Infection by Balkow, Sandra, Kersten, Astrid, Tran, Thi Thanh Thao, Stehle, Thomas, Grosse, Philipp, Museteanu, Crisan, Utermöhlen, Olaf, Pircher, Hanspeter, von Weizsäcker, Fritz, Wallich, Reinhard, Müllbacher, Arno, Simon, Markus M.

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The Outer Surface Protein A of the Spirochete Borrelia burgdorferi is a Plasmin(ogen) Receptor by Fuchs, Hans, Wallich, Reinhard, Simon, Markus M., Kramer, Michael D.

“…The spirochete Borrelia burgdorferi is the causative agent of Lyme borreliosis (Lyme disease) and is transmitted to mammalian hosts by tick vectors. In humans,…”
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Detection of Borrelia burgdorferi sensu lato in lesional skin of patients with erythema migrans and acrodermatitis chronica atrophicans by ospA-specific PCR by MOTER, S. E, HOFMANN, H, WALLICH, R, SIMON, M. M, KRAMER, M. D

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Lyme borreliosis: research gaps and research approaches. Results from an interdisciplinary expert meeting at the Robert Koch Institute by Poggensee, G, Fingerle, V, Hunfeld, K-P, Kraiczy, P, Krause, A, Matuschka, F-R, Richter, D, Simon, M M, Wallich, R, Hofman, H, Kohn, B, Lierz, M, Linde, A, Schneider, T, Straubinger, R, Stark, K, Süss, J, Talaska, T, Jansen, A

“…Lyme borreliosis is currently the most frequent tick-transmitted zoonosis in the northern hemisphere. Germany and other European countries are regarded as…”
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Evaluation of genetic divergence among Borrelia burgdorferi isolates by use of OspA, fla, HSP60, and HSP70 gene probes by Wallich, R, Helmes, C, Schaible, U E, Lobet, Y, Moter, S E, Kramer, M D, Simon, M M

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Differential immune responses to Borrelia burgdorferi in European wild rodent species influence spirochete transmission to Ixodes ricinus L. (Acari: Ixodidae) by KURTENBACH, K, DIZIJ, A, SEITZ, M, MARGOS, G, MOTER, S. E, KRAMER, M. D, WALLICH, R, SCHAIBLE, U. E, SIMON, M. M

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DNA Vaccines Expressing a Fusion Product of Outer Surface Proteins A and C from Borrelia burgdorferi Induce Protective Antibodies Suitable for Prophylaxis but Not for Resolution of Lyme Disease by WALLICH, Reinhard, SIEBERS, Annette, JAHRAUS, Oliver, BRENNER, Christiane, STEHLE, Thomas, SIMON, Markus M

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Differential behaviour of human adult arthrotic chondrocytes under 2D- and 3D-cultivation set-ups in a collagen I gel by Niethard, M, Schneider, U, Wallich, R

“…The aim of this study was to assess the influence of culture conditions on the differentiation of human chondrocytes expanded in monolayer (2 D) or a…”
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Recombinant low-molecular-mass proteins pG and LA7 from Borrelia burgdorferi reveal low diagnostic sensitivity in an enzyme-linked immunosorbent assay by RAUER, Sebastian, WALLICH, Reinhard, NEUBERT, Uwe

“…Serological testing is the most common way of confirming a clinical diagnosis of Lyme disease. There have been numerous efforts to improve the sensitivity and…”
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Strain variation of Lyme disease spirochetes isolated from Ixodes ricinus ticks and rodents collected in two endemic areas in Switzerland by Humair, P F, Peter, O, Wallich, R, Gern, L

“…The relationship among Lyme borreliosis, Borrelia genospecies, rodent reservoirs, and Ixodes ricinus L. ticks was studied in two endemic areas in Switzerland…”
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The Borrelia burgdorferi flagellum-associated 41-kilodalton antigen (flagellin): molecular cloning, expression, and amplification of the gene by WALLICH, R, MOTER, S. E, SIMON, M. M, EBNET, K, HEIBERGER, A, KRAMER, M. D

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Costimulatory Signals for Human T-Cell Activation Induce Nuclear Translocation of pp19/Cofilin by Samstag, Yvonne, Eckerskorn, Christoph, Wesselborg, Sebastian, Henning, Stefan, Wallich, Reinhard, Meuer, Stefan C.

“…Resting T lymphocytes that have recognized antigen bound to a major histocompatibility complex molecule with the T-cell receptor require costimulatory signals…”
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Recombinant Outer Surface Protein A from Borrelia burgdorferi Induces Antibodies Protective against Spirochetal Infection in Mice by Simon, Markus M., Schaible, Ulrich E., Kramer, Michael D., Eckerskorn, Christoph, Museteanu, C., Müller-Hermelink, Hans K., Wallich, Reinhard

“…The outer surface protein A (OspA) of Borrelia burgdorferi was isolated in its native form from strains ZS7 and B31 and as a recombinant protein from strain…”
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LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes by Schraven, B, Schoenhaut, D, Bruyns, E, Koretzky, G, Eckerskorn, C, Wallich, R, Kirchgessner, H, Sakorafas, P, Labkovsky, B, Ratnofsky, S

“…CD45, a leukocyte-specific protein tyrosine phosphatase involved in signal transduction, has previously been shown to associate with a 32-kDa phosphoprotein in…”
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Abrogation of metastatic properties of tumour cells by de novo expression of H-2K antigens following H-2 gene transfection by Wallich, R, Bulbuc, N, Hämmerling, G. J, Katzav, S, Segal, S, Feldman, M

“…H-2 gene transfection was used to restore expression of H-2K antigens in metastatic and non-metastatic subclones of a murine fibrosarcoma that lack their major…”
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Molecular and immunological characterization of a novel polymorphic lipoprotein of Borrelia burgdorferi by WALLICH, R, SIMON, M. M, HOFMANN, H, MOTER, S. E, SCHAIBLE, U. E, KRAMER, M. D

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