Search Results - "Wallet, Pierre"

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11 by Lagrange, Brice, Benaoudia, Sacha, Wallet, Pierre, Magnotti, Flora, Provost, Angelina, Michal, Fanny, Martin, Amandine, Di Lorenzo, Flaviana, Py, Bénédicte F., Molinaro, Antonio, Henry, Thomas

“…Caspase-4/5 in humans and caspase-11 in mice bind hexa-acylated lipid A, the lipid moeity of lipopolysaccharide (LPS), to induce the activation of…”
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Multiple Pseudomonas species secrete exolysin‐like toxins and provoke Caspase‐1‐dependent macrophage death by Basso, Pauline, Wallet, Pierre, Elsen, Sylvie, Soleilhac, Emmanuelle, Henry, Thomas, Faudry, Eric, Attrée, Ina

“…Summary Pathogenic bacteria secrete protein toxins that provoke apoptosis or necrosis of eukaryotic cells. Here, we developed a live‐imaging method, based on…”
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IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection by Wallet, Pierre, Benaoudia, Sacha, Mosnier, Amandine, Lagrange, Brice, Martin, Amandine, Lindgren, Helena, Golovliov, Igor, Michal, Fanny, Basso, Pauline, Djebali, Sophia, Provost, Angelina, Allatif, Omran, Meunier, Etienne, Broz, Petr, Yamamoto, Masahiro, Py, Bénédicte F, Faudry, Eric, Sjöstedt, Anders, Henry, Thomas

“…Guanylate binding proteins (GBPs) are interferon-inducible proteins involved in the cell-intrinsic immunity against numerous intracellular pathogens. The…”
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Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida by Meunier, Etienne, Wallet, Pierre, Dreier, Roland F, Costanzo, Stéphanie, Anton, Leonie, Rühl, Sebastian, Dussurgey, Sébastien, Dick, Mathias S, Kistner, Anne, Rigard, Mélanie, Degrandi, Daniel, Pfeffer, Klaus, Yamamoto, Masahiro, Henry, Thomas, Broz, Petr

“…How host cells induce the release of DNA from cytosolic bacteria is unclear. Broz and colleagues show that the guanylate-binding proteins GBP2 and GBP5 trigger…”
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Circulating immune cell phenotype dynamics reflect the strength of tumor–immune cell interactions in patients during immunotherapy by Griffiths, Jason I., Wallet, Pierre, Pflieger, Lance T., Stenehjem, David, Liu, Xuan, Cosgrove, Patrick A., Leggett, Neena A., McQuerry, Jasmine A., Shrestha, Gajendra, Rossetti, Maura, Sunga, Gemalene, Moos, Philip J., Adler, Frederick R., Chang, Jeffrey T., Sharma, Sunil, Bild, Andrea H.

“…The extent to which immune cell phenotypes in the peripheral blood reflect within-tumor immune activity prior to and early in cancer therapy is unclear. To…”
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The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors by Spaan, András N., Vrieling, Manouk, Wallet, Pierre, Badiou, Cédric, Reyes-Robles, Tamara, Ohneck, Elizabeth A., Benito, Yvonne, de Haas, Carla J. C., Day, Christopher J., Jennings, Michael P., Lina, Gérard, Vandenesch, François, van Kessel, Kok P. M., Torres, Victor J., van Strijp, Jos A. G., Henry, Thomas

“…Evasion of the host phagocyte response by Staphylococcus aureus is crucial to successful infection with the pathogen. γ-haemolysin AB and CB (HlgAB, HlgCB) are…”
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Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data by Liu, Xuan, Gosline, Sara J C, Pflieger, Lance T, Wallet, Pierre, Iyer, Archana, Guinney, Justin, Bild, Andrea H, Chang, Jeffrey T

“…Single-cell RNA sequencing (scRNA-Seq) is an emerging strategy for characterizing immune cell populations. Compared to flow or mass cytometry, scRNA-Seq could…”
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Francisella Inflammasomes: Integrated Responses to a Cytosolic Stealth Bacterium by Wallet, Pierre, Lagrange, Brice, Henry, Thomas

“…Francisella tularensis is a facultative intracellular bacterium causing tularemia, a zoonotic disease. Francisella replicates in the macrophage cytosol and…”
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Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS by Kalvala, Arjun, Wallet, Pierre, Yang, Lu, Wang, Chongkai, Li, Haiqing, Nam, Arin, Nathan, Anusha, Mambetsariev, Isa, Poroyko, Valeriy, Gao, Hanlin, Chu, Peiguo, Sattler, Martin, Bild, Andrea, Manuel, Edwin R., Lee, Peter P., Jolly, Mohit Kumar, Kulkarni, Prakash, Salgia, Ravi

“…Oncogenic (mutant) Ras protein Kirsten rat sarcoma viral oncogene homolog (KRAS) promotes uncontrolled proliferation, altered metabolism, and loss of genome…”
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Abstract 7353: Exploring intrapatient heterogeneity in metastatic breast cancer: Insights into tumor evolution from a warm procurement trial by Bishara, Isaac, Liu, Xuan, Griffiths, Jason, Liu, Jiayi, Cosgrove, Patrick, McQuerry, Jasmine R., Chi, Feng, Wallet, Pierre, Grolmusz, Vince K., Copeland, Benjamin, Pflieger, Lance, Chen, Jinfeng, Majumdar, Sumana, Ronquillo, Grace, Crowder, Terron, Emond, Rena, Factor, Rachel, Barragan, Eliza, Bowtell, David, Cohen, Adam, Schmolze, Daniel D., Lee, Peter, Ihle, Kena, Tumyan, Lusine, Nath, Aritro, Waisman, James, Bild, Andrea, Chang, Jeff

“…Abstract Metastatic breast cancers show variable clinical responses due to inherent heterogeneity, both within tumors and among patients. Studies mainly…”
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IFN-[gamma] extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection by Wallet, Pierre, Benaoudia, Sacha, Mosnier, Amandine, Lagrange, Brice, Martin, Amandine, Lindgren, Helena, Golovliov, Igor, Michal, Fanny, Basso, Pauline, Djebali, Sophia, Provost, Angelina, Allatif, Omran, Meunier, Etienne, Broz, Petr, Yamamoto, Masahiro, Py, Bénédicte F, Faudry, Eric, Sjöstedt, Anders, Henry, Thomas

“…Guanylate binding proteins (GBPs) are interferon-inducible proteins involved in the cell-intrinsic immunity against numerous intracellular pathogens. The…”
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Guanylate-binding proteins promote AIM2 inflammasome activation during Francisella novicida infection by inducing cytosolic bacteriolysis and DNA release by Meunier, Etienne, Wallet, Pierre, Dreier, Roland F., Costanzo, Stéphanie, Anton, Leonie, Rühl, Sebastian, Dussurgey, Sébastien, Dick, Mathias S., Kistner, Anne, Rigard, Mélanie, Degrandi, Daniel, Pfeffer, Klaus, Yamamoto, Masahiro, Henry, Thomas, Broz, Petr

“…The AIM2 inflammasome detects double-stranded DNA in the cytosol and induces caspase-1-dependent pyroptosis as well as release of the inflammatory cytokines…”
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Guanylate binding proteins: new proteins from the cell host cytosol involved in antibacterial immunity by Wallet, Pierre, Lagrange, Brice, Henry, Thomas

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The Staphylococcal Toxins γ-Hemolysin AB and CB Differentially Target Phagocytes by Employing Specific Chemokine Receptors by Spaan, András N., Vrieling, Manouk, Wallet, Pierre, Badiou, Cédric, Reyes-Robles, Tamara, Ohneck, Elizabeth A., Benito, Yvonne, de Haas, Carla J.C., Day, Christopher J., Jennings, Michael P., Lina, Gérard, Vandenesch, François, van Kessel, Kok P.M., Torres, Victor J., van Strijp, Jos A.G., Henry, Thomas

“…Evasion of the host phagocyte response by Staphylococcus aureus is crucial to successful infection with the pathogen. γ-Hemolysin AB and CB (HlgAB, HlgCB) are…”
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The staphylococcal toxins [gamma]-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors by Spaan, András N, Vrieling, Manouk, Wallet, Pierre, Badiou, Cédric, Reyes-robles, Tamara, Ohneck, Elizabeth A, Benito, Yvonne, De Haas, Carla J C, Day, Christopher J, Jennings, Michael P, Lina, Gérard, Vandenesch, François, Van Kessel, Kok P M, Torres, Victor J, Van Strijp, Jos A G, Henry, Thomas

“…Evasion of the host phagocyte response by Staphylococcus aureus is crucial to successful infection with the pathogen. γ-haemolysin AB and CB (HlgAB, HlgCB) are…”
Get full text