Search Results - "Wallert, Mark A."
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Inside Out: Targeting NHE1 as an Intracellular and Extracellular Regulator of Cancer Progression
Published in Chemical biology & drug design (01-01-2013)“…The sodium hydrogen exchanger isoform one is a critical regulator of intracellular pH, serves as an anchor for the formation of cytoplasmic signaling…”
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Sodium hydrogen exchanger (NHE1) palmitoylation and potential functional regulation
Published in Life sciences (1973) (01-01-2022)“…Determine the effect of palmitoylation on the sodium hydrogen exchanger isoform 1 (NHE1), a member of the SLC9 family. NHE1 expressed in native rat tissues or…”
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RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration
Published in Cellular signalling (01-03-2015)“…The sodium hydrogen exchanger isoform one (NHE1) plays a critical role coordinating asymmetric events at the leading edge of migrating cells and is regulated…”
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Bringing the Excitement and Motivation of Research to Students; Using Inquiry and Research-Based Learning in a Year-Long Biochemistry Laboratory: Part I--Guided Inquiry--Purification and Characterization of a Fusion Protein--Histidine Tag, Malate Dehydrogenase, and Green Fluorescent Protein
Published in Biochemistry and molecular biology education (01-09-2010)“…A successful laboratory experience provides the foundation for student success, creating active participation in the learning process. Here, we describe a new…”
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Integrating standard operating procedures and industry notebook standards to evaluate students in laboratory courses
Published in Biochemistry and molecular biology education (01-01-2014)“…To enhance the preparedness of graduates from the Biochemistry and Biotechnology (BCBT) Major at Minnesota State University Moorhead for employment in the…”
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Bringing the Excitement and Motivation of Research to Students; Using Inquiry and Research-Based Learning in a Year-Long Biochemistry Laboratory: Part II--Research-Based Laboratory--A Semester-Long Research Approach Using Malate Dehydrogenase as a Research Model
Published in Biochemistry and molecular biology education (01-09-2010)“…Research-based learning in a teaching environment is an effective way to help bring the excitement and experience of independent bench research to a large…”
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Investigating the Role of NHE1 in Idiopathic Pulmonary Fibrosis
Published in The FASEB journal (01-04-2020)“…Abstract only Idiopathic pulmonary fibrosis is a chronic lung disorder characterized by thickening, stiffening and scaring of tissue within the lungs. Affected…”
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Investigating the Potential of NHE1 Inhibitors as Potential Adjuvant Therapies in the Treatment of Ovarian Cancer
Published in The FASEB journal (01-04-2020)“…Abstract only Each year in the United States over 200,000 women are diagnosed with ovarian cancer leading to more than 14,000 deaths. Increases in the…”
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Characterizing the Role of the Na + ‐H + Exchanger Isoform 1 (NHE1) in Pulmonary Fibrosis
Published in The FASEB journal (01-04-2020)“…Abstract only Pulmonary fibrosis is a chronic, progressive lung disease characterized by stiffening and thickening of the lung tissue leading to reduced…”
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The Interplay between Palmitoylation and Phosphorylation of NHE1 in the Regulation of Cell Proliferation
Published in The FASEB journal (01-04-2020)“…Abstract only The Na + ‐H + Exchanger Isoform 1 (NHE1) is key to the regulation of cell cycle progression and cell proliferation. NHE1 is a 12‐pass…”
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alpha(1)-Adrenergic receptor stimulation of cell motility requires phospholipase D-mediated extracellular signal-regulated kinase activation
Published in Chemical biology & drug design (01-04-2007)“…Phospholipase D is suspected to play a role in tumorigenesis, and the inhibition of phospholipase D has been associated with changes in several cellular events…”
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Regulation of Cellular Proliferation and Migration by Palmitoylation of the Na + ‐H + Exchanger Isoform 1 (NHE1)
Published in The FASEB journal (01-04-2020)“…Abstract only The Na + ‐H + Exchanger Isoform 1 (NHE1) is an important factor in cellular proliferation and migration of cells in both healthy and diseased…”
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Identifying Kinase Inhibitors as Potential Adjuvant Chemotherapeutics in Treatment for Ovarian Cancer
Published in The FASEB journal (01-04-2020)“…Abstract only In the United States, 22,000 women are diagnosed with ovarian cancer annually resulting in 14,000 deaths. This makes ovarian cancer the fifth…”
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Is Less Actually More? Investigating the Synergistic Relationship between Chemotherapy Agents and NHE1 Inhibitors in Ovarian Cancer Cells
Published in The FASEB journal (01-04-2019)“…Chemotherapeutic regimens continue to be the conventional therapy utilized in the treatment of ovarian cancer. These treatment plans often include the use of…”
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Investigating the Role of Inhibitors of NHE1 Activation as Potential Adjuvant Therapies in the Treatment of Ovarian Cancer
Published in The FASEB journal (01-04-2019)“…Each year in the United States over 22,000 women are diagnosed with ovarian cancer leading to more than 14,000 deaths. Increases in the expression and activity…”
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Evaluating the Role of NHE1 Palmitoylation in the Regulation of Cell Proliferation and Migration
Published in The FASEB journal (01-04-2019)“…The Na+‐ H+ Exchanger Isoform I (NHE1) is a key regulator of cell proliferation and migration in a range of cell types. Activation of NHE1 is an initial step…”
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Hypoxia and Serum‐Deprivation Impacts Calcineurin B Homologous Protein Isoform 2 Expression and Activity in Non‐Small Cell Lung Cancer
Published in The FASEB journal (01-04-2017)“…Abstract only The Na + ‐ H + exchanger isoform 1 (NHE1) is a key regulator of cell proliferation, migration and invasion in cells from a variety of solid…”
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The Role of the Na + ‐H + Exchanger Isoform 1 (NHE1) and Calcineurin B Homologous Protein Isoform 2 (CHP2) on Cell Proliferation and Migration in Squamous Cell Carcinoma of the Lung
Published in The FASEB journal (01-04-2017)“…Abstract only Lung cancer is a debilitating disease affecting thousands of people worldwide. Approximately 80% of lung cancers are comprised of non‐small cell…”
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The Phosphorylation of the Na + ‐H + Exchanger Isoform I (NHE1) and Its Role in the Regulation of Cell Proliferation and Migration
Published in The FASEB journal (01-04-2017)“…Abstract only The hallmarks of cancer are a collection of phenotypic changes that define cancer development and progression. Two of these hallmarks, sustaining…”
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The Effect of Proline Rich Tyrosine Kinase 2 Activity on the Na + ‐H + Exchanger Isoform 1 Regulation of Cell Proliferation and Migration
Published in The FASEB journal (01-04-2017)“…Abstract only The Na + ‐H + exchanger isoform 1 (NHE1) is a 12‐pass transmembrane protein that functions by exchanging one extracellular sodium ion for one…”
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