Search Results - "Waller, Kimberly A."

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  1. 1

    The biology of Lubricin: Near frictionless joint motion by Jay, Gregory D., Waller, Kimberly A.

    Published in Matrix biology (01-10-2014)
    “…Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an important role in cartilage integrity. In healthy joints,…”
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    Journal Article
  2. 2

    Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis by Waller, Kimberly A., Zhang, Ling X., Elsaid, Khaled A., Fleming, Braden C., Warman, Matthew L., Jay, Gregory D.

    “…Osteoarthritis is a complex disease involving the mechanical breakdown of articular cartilage in the presence of altered joint mechanics and chondrocyte death,…”
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    Journal Article
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    Friction-Induced Mitochondrial Dysregulation Contributes to Joint Deterioration in Prg4 Knockout Mice by Waller, Kimberly A, Zhang, Ling X, Jay, Gregory D

    “…Deficiency of PRG4 (lubricin), the boundary lubricant in mammalian joints, contributes to increased joint friction accompanied by superficial and upper…”
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    Journal Article
  5. 5

    Lubricin Restoration in a Mouse Model of Congenital Deficiency by Hill, Adele, Waller, Kimberly A., Cui, Yajun, Allen, Justin M., Smits, Patrick, Zhang, Ling X., Ayturk, Ugur M., Hann, Steven, Lessard, Samantha G., Zurakowski, David, Warman, Matthew L., Jay, Gregory D.

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2015)
    “…Objective Congenital deficiency of the principal boundary lubricant in cartilage (i.e., lubricin, encoded by the gene PRG4) increases joint friction and causes…”
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    Journal Article
  6. 6

    Transcriptional profiling of articular cartilage in a porcine model of early post‐traumatic osteoarthritis by Sieker, Jakob T., Proffen, Benedikt L., Waller, Kimberly A., Chin, Kaitlyn E., Karamchedu, Naga Padmini, Akelman, Matthew R., Perrone, Gabriel S., Kiapour, Ata M., Konrad, Johannes, Murray, Martha M., Fleming, Braden C.

    Published in Journal of orthopaedic research (01-01-2018)
    “…ABSTRACT To identify the molecular pathophysiology present in early post‐traumatic osteoarthritis (PTOA), the transcriptional profile of articular cartilage…”
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    Journal Article
  7. 7

    Transcriptional profiling of synovium in a porcine model of early post‐traumatic osteoarthritis by Sieker, Jakob T., Proffen, Benedikt L., Waller, Kimberly A., Chin, Kaitlyn E., Karamchedu, Naga Padmini, Akelman, Matthew R., Perrone, Gabriel S., Kiapour, Ata M., Konrad, Johannes, Fleming, Braden C., Murray, Martha M.

    Published in Journal of orthopaedic research (01-08-2018)
    “…ABSTRACT To determine the transcriptional profile of synovium during the molecular phase of post‐traumatic osteoarthritis, anterior cruciate ligament…”
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  8. 8

    Superficial zone cellularity is deficient in mice lacking lubricin: a stereoscopic analysis by Karamchedu, Naga Padmini, Tofte, Josef N, Waller, Kimberly A, Zhang, Ling X, Patel, Tarpit K, Jay, Gregory D

    Published in Arthritis research & therapy (14-03-2016)
    “…Lubricin, a mucinous glycoprotein secreted by synoviocytes and chondrocytes plays an important role in reducing the coefficient of friction in mammalian…”
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    Journal Article
  9. 9

    Preventing Friction-induced Chondrocyte Apoptosis: Comparison of Human Synovial Fluid and Hylan G-F 20 by WALLER, Kimberly A, ZHANG, Ling X, FLEMING, Braden C, JAY, Gregory D

    Published in Journal of rheumatology (01-07-2012)
    “…Symptomatic osteoarthritis (OA) is a common painful disease with limited treatment options. A rising number of patients with OA have been treated with…”
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    Using a Symbolic Interactionist Approach to Role and Identity to Illuminate Medical Student Avoidance of Primary Care by Waller, Kimberly A.

    “…A symbolic interactionist approach is presented and analyzed in reference to helping solve the problem of medical students not choosing primary care practice…”
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