Search Results - "Walle, R."

A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic by Shapira, Tirosh, Monreal, I. Abrrey, Dion, Sébastien P., Buchholz, David W., Imbiakha, Brian, Olmstead, Andrea D., Jager, Mason, Désilets, Antoine, Gao, Guang, Martins, Mathias, Vandal, Thierry, Thompson, Connor A. H., Chin, Aaleigha, Rees, William D., Steiner, Theodore, Nabi, Ivan Robert, Marsault, Eric, Sahler, Julie, Diel, Diego G., Van de Walle, Gerlinde R., August, Avery, Whittaker, Gary R., Boudreault, Pierre-Luc, Leduc, Richard, Aguilar, Hector C., Jean, François

“…The COVID-19 pandemic caused by the SARS-CoV-2 virus remains a global public health crisis. Although widespread vaccination campaigns are underway, their…”
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Antimicrobial peptides secreted by equine mesenchymal stromal cells inhibit the growth of bacteria commonly found in skin wounds by Harman, Rebecca M, Yang, Steven, He, Megan K, Van de Walle, Gerlinde R

“…The prevalence of chronic skin wounds in humans is high, and treatment is often complicated by the presence of pathogenic bacteria. Therefore, safe and…”
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Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis by Tomlinson, Joy E, Wolfisberg, Raphael, Fahnøe, Ulrik, Sharma, Himanshu, Renshaw, Randall W, Nielsen, Louise, Nishiuchi, Eiko, Holm, Christina, Dubovi, Edward, Rosenberg, Brad R, Tennant, Bud C, Bukh, Jens, Kapoor, Amit, Divers, Thomas J, Rice, Charles M, Van de Walle, Gerlinde R, Scheel, Troels K H

“…Pegiviruses frequently cause persistent infection (as defined by >6 months), but unlike most other Flaviviridae members, no apparent clinical disease. Human…”
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Secreted sphingomyelins modulate low mammary cancer incidence observed in certain mammals by Ledet, Melissa M., Harman, Rebecca M., Fan, Jennifer C., Schmitt-Matzen, Emily, Diaz-Rubio, Maria Elena, Zhang, Sheng, Van de Walle, Gerlinde R.

“…Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel…”
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Peripheral Blood‐Derived Mesenchymal Stromal Cells Promote Angiogenesis via Paracrine Stimulation of Vascular Endothelial Growth Factor Secretion in the Equine Model by Bussche, Leen, Van de Walle, Gerlinde R.

“…The presence of angiogenic‐stimulating factors in conditioned medium (CM) of peripheral blood‐derived equine mesenchymal stromal cells (PB‐MSCs) was examined,…”
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A semantic rule checking environment for building performance checking by Pauwels, P., Van Deursen, D., Verstraeten, R., De Roo, J., De Meyer, R., Van de Walle, R., Van Campenhout, J.

“…Today's construction industry relies heavily on high-performing building information modelling (BIM) systems. By deploying the Industry Foundation Classes…”
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Beyond tradition and convention: benefits of non-traditional model organisms in cancer research by Harman, Rebecca M., Das, Sanjna P., Bartlett, Arianna P., Rauner, Gat, Donahue, Leanne R., Van de Walle, Gerlinde R.

“…Traditional laboratory model organisms are indispensable for cancer research and have provided insight into numerous mechanisms that contribute to cancer…”
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Scalable Feature‐Preserving Irregular Mesh Coding by El Sayeh Khalil, J., Munteanu, A., Denis, L., Lambert, P., Walle, R.

“…This paper presents a novel wavelet‐based transform and coding scheme for irregular meshes. The transform preserves geometric features at lower resolutions by…”
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Identification and Characterization of Equine Herpesvirus Type 1 pUL56 and Its Role in Virus-Induced Downregulation of Major Histocompatibility Complex Class I by Ma, Guanggang, Feineis, Silke, Osterrieder, Nikolaus, Van de Walle, Gerlinde R

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tropism, pathology, and transmission of equine parvovirus-hepatitis by Tomlinson, Joy Ellen, Jager, Mason, Struzyna, Alyssa, Laverack, Melissa, Fortier, Lisa Ann, Dubovi, Edward, Foil, Lane D., Burbelo, Peter D., Divers, Thomas J., Van de Walle, Gerlinde R.

“…Equine parvovirus-hepatitis (EqPV-H) has recently been associated with cases of Theiler's disease, a form of fulminant hepatic necrosis in horses. To assess…”
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Bovine milk-derived cells express transcriptome markers of pluripotency and secrete bioactive factors with regenerative and antimicrobial activity by Danev, Nikola, Harman, Rebecca M., Oliveira, Leane, Huntimer, Lucas, Van de Walle, Gerlinde R.

“…The bovine mammary stem/progenitor cell secretome stimulates regeneration in vitro and contains proteins associated with antimicrobial defense. This has led to…”
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Nasal transmission of equine parvovirus hepatitis by Tomlinson, Joy E., Van de Walle, Gerlinde R.

“…Background Equine parvovirus hepatitis (EqPV‐H) is highly prevalent and causes subclinical to fatal hepatitis, which can occur in outbreaks. Whereas iatrogenic…”
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The mesenchymal stromal cell secretome impairs methicillin‐resistant Staphylococcus aureus biofilms via cysteine protease activity in the equine model by Marx, Charlotte, Gardner, Sophia, Harman, Rebecca M., Van de Walle, Gerlinde R.

“…Mesenchymal stromal cells (MSCs) from various species, such as humans, mice, and horses, were recently found to effectively inhibit the growth of various…”
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Small but mighty: old and new parvoviruses of veterinary significance by Jager, Mason C, Tomlinson, Joy E, Lopez-Astacio, Robert A, Parrish, Colin R, Van de Walle, Gerlinde R

“…In line with the Latin expression "sed parva forti" meaning "small but mighty," the family Parvoviridae contains many of the smallest known viruses, some of…”
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Mesenchymal stromal cell‐secreted CCL2 promotes antibacterial defense mechanisms through increased antimicrobial peptide expression in keratinocytes by Marx, Charlotte, Gardner, Sophia, Harman, Rebecca M., Wagner, Bettina, Van de Walle, Gerlinde R.

“…Mesenchymal stromal cells (MSCs) from both humans and horses, which represent a clinically relevant translation animal model for human cutaneous wound healing,…”
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A Single‐Nucleotide Polymorphism in a Herpesvirus DNA Polymerase Is Sufficient to Cause Lethal Neurological Disease by Van de Walle, Gerlinde R. , Goupil, Ryan , Wishon, Cassandra , Damiani, Armando , Perkins, Gillian A. , Osterrieder, Nikolaus 

“…Epidemiological studies have shown that a single‐nucleotide polymorphism in the equid herpesvirus type 1 DNA polymerase gene is associated with outbreaks of…”
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Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet + B cells by Patel, Roosheel S, Tomlinson, Joy E, Divers, Thomas J, Van de Walle, Gerlinde R, Rosenberg, Brad R

“…Traditional laboratory model organisms represent a small fraction of the diversity of multicellular life, and findings in any given experimental model often do…”
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Pathogenesis, MicroRNA‐122 Gene‐Regulation, and Protective Immune Responses After Acute Equine Hepacivirus Infection by Tomlinson, Joy E., Wolfisberg, Raphael, Fahnøe, Ulrik, Patel, Roosheel S., Trivedi, Sheetal, Kumar, Arvind, Sharma, Himanshu, Nielsen, Louise, McDonough, Sean P., Bukh, Jens, Tennant, Bud C., Kapoor, Amit, Rosenberg, Brad R., Rice, Charles M., Divers, Thomas J., Van de Walle, Gerlinde R., Scheel, Troels K.H.

“…Background and Aims Equine hepacivirus (EqHV) is phylogenetically the closest relative of HCV and shares genome organization, hepatotropism, transient or…”
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Tendon Regeneration in Human and Equine Athletes: Ubi Sumus-Quo Vadimus (Where are We and Where are We Going to)? by Spaas, Jan H., Guest, Deborah J., Van de Walle, Gerlinde R.

“…Tendon injuries are one of the most common orthopaedic problems in both human and equine athletes. When a damaged tendon heals naturally, it loses a…”
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Preliminary in vivo investigation of the mesenchymal stromal cell secretome as a novel treatment for methicillin‐resistant Staphylococcus aureus in equine skin wounds by Fahey, Megan J., Harman, Rebecca M., Thomas, Matthew A., Pugliese, Brenna R., Peters‐Kennedy, Jeanine, Delco, Michelle L., Van de Walle, Gerlinde R.

“…Objective We aimed to study the antimicrobial and pro‐healing potential of equine mesenchymal stromal cell secreted products (i.e. secretome), collected as…”
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