Search Results - "Wallach, Brenda"

Construction and Characterization of a Conditionally Active Version of the Serine/Threonine Kinase Akt by Kohn, A D, Barthel, A, Kovacina, K S, Boge, A, Wallach, B, Summers, S A, Birnbaum, M J, Scott, P H, Lawrence, Jr, J C, Roth, R A

“…Akt is a serine/threonine kinase that requires a functional phosphatidylinositol 3-kinase to be stimulated by insulin and other growth factors. When directed…”
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Comparison of the Signaling Abilities of the Cytoplasmic Domains of the Insulin Receptor and the Insulin Receptor-Related Receptor in 3T3-L1 Adipocytes by Dandekar, Ajai A., Wallach, Brenda J., Barthel, Andreas, Roth, Richard A.

“…Abstract In the present work a chimeric receptor containing the intracellular domain of the insulin receptor-related receptor (IRR) and the extracellular…”
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Role of the time factor in signaling specificity: Application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases by De Meyts, Pierre, Christoffersen, Claus T., Ursø, Birgitte, Wallach, Brenda, Grønskov, Karen, Yakushiji, Fumiatsu, Shymko, Ronald M.

“…The signal transduction pathways activated by hormones, growth factors, and cytokines show an extraordinary degree of cross-talk and redundancy. This review…”
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Engineering the C-region of human insulin-like growth factor-1: implications for receptor binding by Gill, Raj, Wallach, Brenda, Verma, Chandra, Ursø, Birgitte, De Wolf, Elke, Grötzinger, Joachim, Murray-Rust, Judith, Pitts, Jim, Wollmer, Axel, De Meyts, Pierre, Wood, Steve

“…Recombinant wild-type human IGF-1 and a C-region mutant in which residues 28–37 have been replaced by a 4-glycine bridge (4-Gly IGF-1) were secreted and…”
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Modelling of the disulphide-swapped isomer of human insulin-like growth factor-1: implications for receptor binding by Gill, Raj, Verma, Chandra, Wallach, Brenda, Ursø, Birgitte, Pitts, Jim, Wollmer, Axel, De Meyts, Pierre, Wood, Steve

“…Insulin-like growth factor-1 (IGF-1) is a serum protein which unexpectedly folds to yield two stable tertiary structures with different disulphide…”
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Comparison of the Signaling Abilities of the Cytoplasmic Domains of the Insulin Receptor and the Insulin Receptor-Related Receptor in 3T3-L1 Adipocytes 1 by Dandekar, Ajai A., Wallach, Brenda J., Barthel, Andreas, Roth, Richard A.

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Comparison of the Signaling Abilities of the Cytoplasmic Domains of the Insulin Receptor and the Insulin Receptor-Related Receptor in 3T3-L1 Adipocytes1 by Dandekar, Ajai A, Wallach, Brenda J, Barthel, Andreas, Roth, Richard A

“…In the present work a chimeric receptor containing the intracellular domain of the insulin receptor-related receptor (IRR) and the extracellular domain of the…”
Get full text