Search Results - "Wallace, H. B."
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Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
Published in BMC medicine (04-12-2020)“…Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on…”
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Do Phthalates Affect Steroidogenesis by the Human Fetal Testis? Exposure of Human Fetal Testis Xenografts to Di-n-Butyl Phthalate
Published in The journal of clinical endocrinology and metabolism (01-03-2012)“…Context: Phthalates are ubiquitous environmental chemicals. Fetal exposure to certain phthalates [e.g. di-n-butyl phthalate (DBP)] causes masculinization…”
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Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system
Published in Molecular human reproduction (01-03-2018)“…Abstract STUDY QUESTION Can complete oocyte development be achieved from human ovarian tissue containing primordial/unilaminar follicles and grown in vitro in…”
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The immature human ovary shows loss of abnormal follicles and increasing follicle developmental competence through childhood and adolescence
Published in Human reproduction (Oxford) (01-01-2014)“…STUDY QUESTION Do the ovarian follicles of children and adolescents differ in their morphology and in vitro growth potential from those of adults? SUMMARY…”
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Ovarian cryopreservation for fertility preservation: indications and outcomes
Published in Reproduction (Cambridge, England) (01-12-2008)“…Female fertility preservation provides significantly different challenges to that for the male, with the only established method being cryopreservation of…”
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Measuring anti-Müllerian hormone for the assessment of ovarian reserve: When and for whom is it indicated?
Published in Maturitas (01-01-2012)“…Abstract Our understanding of female reproductive function has been hampered by our inability to directly assess the number of non-growing primordial follicles…”
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Re-implantation of cryopreserved ovarian cortex resulting in restoration of ovarian function, natural conception and successful pregnancy after haematopoietic stem cell transplantation for Wilms tumour
Published in Journal of assisted reproduction and genetics (01-12-2016)“…With the improvement of long-term cancer survival rates, growing numbers of female survivors are suffering from treatment-related premature ovarian…”
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Physiological sex steroid replacement in premature ovarian failure: randomized crossover trial of effect on uterine volume, endometrial thickness and blood flow, compared with a standard regimen
Published in Human reproduction (Oxford) (01-04-2012)“…BACKGROUND Premature ovarian failure (POF) is currently managed by non-physiological sex steroid regimens which are inadequate at optimizing uterine…”
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Germ cell differentiation in the marmoset (Callithrix jacchus) during fetal and neonatal life closely parallels that in the human
Published in Human reproduction (Oxford) (01-12-2008)“…BACKGROUND Testicular germ cell tumours (TGCT) are thought to originate from fetal germ cells that fail to differentiate normally, but no animal model for…”
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An externally validated age-related model of mean follicle density in the cortex of the human ovary
Published in Journal of assisted reproduction and genetics (01-07-2015)“…Purpose The ability to accurately estimate a woman’s ovarian reserve by non-invasive means is the goal of ovarian reserve prediction. It is not known whether a…”
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Subfertility in children and young people treated for solid and haematological malignancies
Published in British journal of haematology (01-10-2005)“…Summary Children treated for cancer may exhibit impaired fertility in later life. A number of chemotherapeutic agents have been identified as being…”
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Survivors of childhood cancer lost to follow-up can be re-engaged into active long-term follow-up by a postal health questionnaire intervention
Published in European journal of cancer (1990) (01-05-2012)“…Abstract Lifelong long-term follow-up (LTFU) is recommended for all survivors of childhood cancer. National guidelines recommend risk-stratified levels of…”
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Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium
Published in The lancet oncology (01-02-2017)“…Summary Treatment with chemotherapy, radiotherapy, or surgery that involves reproductive organs can cause impaired spermatogenesis, testosterone deficiency,…”
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Interleukin-10 Reduces Morbidity and Mortality in Murine Multiple Organ Dysfunction Syndrome (MODS)
Published in The Journal of surgical research (01-07-1998)“…Hypothesis.IL-10 will reduce morbidity and mortality in murine MODS. Introduction.Intraperitoneal (ip) zymosan causes a triphasic inflammatory process leading…”
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Non-growing follicle density is increased following adriamycin, bleomycin, vinblastine and dacarbazine (ABVD) chemotherapy in the adult human ovary
Published in Human reproduction (Oxford) (01-01-2017)“…STUDY QUESTION Do the chemotherapeutic regimens of ABVD (adriamycin, bleomycin, vinblastine and dacarbazine) or OEPA-COPDAC (combined vincristine, etoposide,…”
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Data-driven assessment of the human ovarian reserve
Published in Molecular human reproduction (01-02-2012)“…Human ovarian physiology is still poorly understood, with the factors and mechanisms that control initiation of follicular recruitment and loss remaining…”
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Fertility preservation for children treated for cancer (1): scientific advances and research dilemmas
Published in Archives of disease in childhood (01-04-2001)“…Most children treated for cancer can now expect to be cured and to be fertile. However, in a significant minority, future fertility may be compromised by their…”
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Is inhibin B a potential marker of gonadotoxicity in prepubertal children treated for cancer?
Published in Clinical endocrinology (Oxford) (01-03-2003)“…Summary background and objective Chemotherapy treatment of childhood cancer may impair gonadal function, which may be manifested only in adulthood as permanent…”
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The radiosensitivity of the human oocyte
Published in Human reproduction (Oxford) (01-01-2003)“…BACKGROUND: We determined the best model available for natural follicle decline in healthy women and used this to calculate the radiosensitivity of the human…”
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Fertility preservation for children treated for cancer (2): ethics of consent for gamete storage and experimentation
Published in Archives of disease in childhood (01-04-2001)“…Phase 1 Develop a consensus of treatment related risks of germ cell damage Develop a consensus of risks to the child associated with germ cell harvest Phase 2…”
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