Search Results - "Wallace, Andrew"

Neighbourhood Change, Deprivation, Peripherality, and Ageing in the Yorkshire Coalfield by Wallace, Andrew

“…Low‐income neighbourhoods in contemporary England continue to be buffeted by roiling economic inequalities and social policy absences. Long‐term residents have…”
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New challenges for BRCA testing: a view from the diagnostic laboratory by Wallace, Andrew J

“…Increased demand for BRCA testing is placing pressures on diagnostic laboratories to raise their mutation screening capacity and handle the challenges…”
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Gentrification Interrupted in Salford, UK: From New Deal to "Limbo-Land" in a Contemporary Urban Periphery by Wallace, Andrew

“…This paper examines two potential lacunae in understanding low‐income residents’ experiences of contemporary state‐led gentrification via a study of…”
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The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study by Ryan, Neil A. J., McMahon, Raymond, Tobi, Simon, Snowsill, Tristan, Esquibel, Shona, Wallace, Andrew J., Bunstone, Sancha, Bowers, Naomi, Mosneag, Ioana E., Kitson, Sarah J., O’Flynn, Helena, Ramchander, Neal C., Sivalingam, Vanitha N., Frayling, Ian M., Bolton, James, McVey, Rhona J., Evans, D. Gareth, Crosbie, Emma J.

“…Selecting test populations by age and/or family history, failure to apply reference standard tests consistently, and poor conversion to definitive testing are…”
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Schwannomatosis: a genetic and epidemiological study by Evans, D Gareth, Bowers, Naomi L, Tobi, Simon, Hartley, Claire, Wallace, Andrew J, King, Andrew T, Lloyd, Simon K W, Rutherford, Scott A, Hammerbeck-Ward, Charlotte, Pathmanaban, Omar N, Freeman, Simon R, Ealing, John, Kellett, Mark, Laitt, Roger, Thomas, Owen, Halliday, Dorothy, Ferner, Rosalie, Taylor, Amy, Duff, Chris, Harkness, Elaine F, Smith, Miriam J

“…ObjectivesSchwannomatosis is a dominantly inherited condition predisposing to schwannomas of mainly spinal and peripheral nerves with some diagnostic overlap…”
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New challenges for BRCA testing: a view from the diagnostic laboratory by Wallace, Andrew J

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A Land Plant-Specific Transcription Factor Directly Enhances Transcription of a Pathogenic Noncoding RNA Template by DNA-Dependent RNA Polymerase II by Wang, Ying, Qu, Jie, Ji, Shaoyi, Wallace, Andrew J., Wu, Jian, Li, Yi, Gopalan, Venkat, Ding, Biao

“…Some DNA-dependent RNA polymerases (DdRPs) possess RNA-dependent RNA polymerase activity, as was first discovered in the replication of Potato spindle tuber…”
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A Dominantly Inherited 5′ UTR Variant Causing Methylation-Associated Silencing of BRCA1 as a Cause of Breast and Ovarian Cancer by Evans, D.Gareth R., van Veen, Elke M., Byers, Helen J., Wallace, Andrew J., Ellingford, Jamie M., Beaman, Glenda, Santoyo-Lopez, Javier, Aitman, Timothy J., Eccles, Diana M., Lalloo, Fiona I., Smith, Miriam J., Newman, William G.

“…Pathogenic variants in BRCA1 or BRCA2 are identified in ∼20% of families with multiple individuals affected by early-onset breast and/or ovarian cancer…”
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Design and Evaluation of Multispectral LiDAR for the Recovery of Arboreal Parameters by Wallace, Andrew M., McCarthy, Aongus, Nichol, Caroline J., Ximing Ren, Morak, Simone, Martinez-Ramirez, Daniel, Woodhouse, Iain H., Buller, Gerald S.

“…Multispectral light detection and ranging (LiDAR) has the potential to recover structural and physiological data from arboreal samples and, by extension, from…”
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Efficiency of xylanases from families 10 and 11 in production of xylo-oligosaccharides from wheat arabinoxylans by Morgan, Natalie K., Wallace, Andrew, Bedford, Michael R., Choct, Mingan

“…•Xylan hydrolysis is superior with family 10 xylanase compared to family 11 or 10&11.•The pH optimum for hydrolysis of xylan into small xylo-oligosaccharides…”
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Estimating Fog Parameters from an Image Sequence using Non-linear Optimisation by Ding, Yining, Wallace, Andrew M., Wang, Sen

“…Given a sequence of images taken in foggy weather, we seek to estimate the atmospheric light and the scattering coefficient. These are key parameters to…”
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Revisiting neurofibromatosis type 2 diagnostic criteria to exclude LZTR1-related schwannomatosis by Smith, Miriam J, Bowers, Naomi L, Bulman, Michael, Gokhale, Carolyn, Wallace, Andrew J, King, Andrew T, Lloyd, Simon K.L, Rutherford, Scott A, Hammerbeck-Ward, Charlotte L, Freeman, Simon R, Evans, D Gareth

“…OBJECTIVE:To determine the specificity of the current clinical diagnostic criteria for neurofibromatosis type 2 (NF2) relative to the requirement for…”
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Full Waveform LiDAR for Adverse Weather Conditions by Wallace, Andrew M., Halimi, Abderrahim, Buller, Gerald S.

“…We present and discuss the case for full waveform pixel and image acquisition and processing to enable LiDAR sensors to penetrate and reconstruct 3D surface…”
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30 year experience of index case identification and outcomes of cascade testing in high-risk breast and colorectal cancer predisposition genes by Woodward, Emma R, Green, Kate, Burghel, George J, Bulman, Michael, Clancy, Tara, Lalloo, Fiona, Schlecht, Helene, Wallace, Andrew J, Evans, D Gareth

“…It is 30 years since the first diagnostic cancer predisposition gene (CPG) test in the Manchester Centre for Genomic Medicine (MCGM), providing opportunities…”
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Combining evidence for and against pathogenicity for variants in cancer susceptibility genes: CanVIG-UK consensus recommendations by Garrett, Alice, Durkie, Miranda, Callaway, Alison, Burghel, George J, Robinson, Rachel, Drummond, James, Torr, Bethany, Cubuk, Cankut, Berry, Ian R, Wallace, Andrew J, Ellard, Sian, Eccles, Diana M, Tischkowitz, Marc, Hanson, Helen, Turnbull, Clare

“…Accurate classification of variants in cancer susceptibility genes (CSGs) is key for correct estimation of cancer risk and management of patients. Consistency…”
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The utility of TP53 and PIK3CA mutations as prognostic biomarkers in salivary adenoid cystic carcinoma by Adderley, Helen, Rack, Samuel, Hapuarachi, Brindley, Feeney, Laura, Morgan, David, Hussell, Tracy, Wallace, Andrew J, Betts, Guy, Hodgson, Clare, Harrington, Kevin, Metcalf, Robert

“…•Largest published ACC clinical-genomics dataset.•TP53-mutated ACC had significantly shorter median OS vs. TP53 wild-type ACC.•Stratifying by TP53 status may…”
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Pathology update to the Manchester Scoring System based on testing in over 4000 families by Evans, D Gareth, Harkness, Elaine F, Plaskocinska, Inga, Wallace, Andrew J, Clancy, Tara, Woodward, Emma R, Howell, Tony A, Tischkowitz, Marc, Lalloo, Fiona

“…While the requirement for thresholds for testing for mutations in is being questioned, they are likely to remain for individuals unaffected by a relevant…”
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Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas by Smith, Miriam J, Wallace, Andrew J, Bennett, Chris, Hasselblatt, Martin, Elert-Dobkowska, Ewelina, Evans, Linton T, Hickey, William F, van Hoff, Jack, Bauer, David, Lee, Amy, Hevner, Robert F, Beetz, Christian, du Plessis, Daniel, Kilday, John-Paul, Newman, William G, Evans, D Gareth

“…We recently reported SMARCE1 mutations as a cause of spinal clear cell meningiomas. Here, we have identified five further cases with non‐NF2 spinal meningiomas…”
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Long-term correlation tracking using multi-layer hybrid features in sparse and dense environments by Baisa, Nathanael L., Bhowmik, Deepayan, Wallace, Andrew

“…•We integrate a hybrid of CNN and hand-crafted features to learn a correlation filter.•We incorporate a re-detector to re-initialise the tracker in case of…”
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Arthroscopic Bankart repair with remplissage for non-engaging Hill-Sachs lesion in professional collision athletes by Domos, Peter, Ascione, Francesco, Wallace, Andrew L.

“…Background The present study aimed to determine whether arthroscopic remplissage with Bankart repair is an effective treatment for improving outcomes for…”
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