Search Results - "Walker II, William H."
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Mammary Tumors Induce Central Pro-inflammatory Cytokine Expression, but Not Behavioral Deficits in Balb/C Mice
Published in Scientific reports (15-08-2017)“…Breast cancer survivors are more likely to develop mood disorders and cognitive deficits than women in the general population. Previous studies suggest that…”
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Social enrichment alters the response of brain leukocytes to chemotherapy and tumor development in aged mice
Published in Heliyon (15-01-2024)“…Aging is a risk factor for the development of breast cancer. Foundational science studies have supported associations among neuroinflammation, breast cancer,…”
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A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast Cancer
Published in Cell metabolism (03-07-2018)“…We investigated relationships among immune, metabolic, and sleep abnormalities in mice with non-metastatic mammary cancer. Tumor-bearing mice displayed…”
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Time-of-Day Dictates Transcriptional Inflammatory Responses to Cytotoxic Chemotherapy
Published in Scientific reports (24-01-2017)“…Many cytotoxic chemotherapeutics elicit a proinflammatory response which is often associated with chemotherapy-induced behavioral alterations. The immune…”
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Commentary: Anxiety- and Depression-like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice
Published in Frontiers in behavioral neuroscience (24-06-2016)“…The hippocampus has become central in affective disorder research because blocking hippocampal neurogenesis eliminates some beneficial effects of monoaminergic…”
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Acute exposure to low-level light at night is sufficient to induce neurological changes and depressive-like behavior
Published in Molecular psychiatry (01-05-2020)“…The advent and wide-spread adoption of electric lighting over the past century has profoundly affected the circadian organization of physiology and behavior…”
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Global climate change and invariable photoperiods: A mismatch that jeopardizes animal fitness
Published in Ecology and evolution (01-09-2019)“…The Earth's surface temperature is rising, and precipitation patterns throughout the Earth are changing; the source of these shifts is likely anthropogenic in…”
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Circadian Rhythm Disruption in Cancer Survivors: From Oncogenesis to Quality of Life
Published in Cancer medicine (Malden, MA) (01-10-2024)“…ABSTRACT Background Circadian rhythms are approximately 24‐hour cycles in physiological and behavioral processes. They are entrained to the external solar day…”
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Acute exposure to artificial light at night alters hippocampal vascular structure in mice
Published in iScience (21-07-2023)“…The structure and function of the cardiovascular system are modulated across the day by circadian rhythms, making this system susceptible to circadian rhythm…”
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Dim light at night shifts microglia to a pro-inflammatory state after cerebral ischemia, altering stroke outcome in mice
Published in Experimental neurology (01-07-2024)“…Circadian rhythms are endogenous biological cycles that regulate physiology and behavior and are set to precisely 24-h by light exposure. Light at night (LAN)…”
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The Ventral Tegmental Area and Nucleus Accumbens as Circadian Oscillators: Implications for Drug Abuse and Substance Use Disorders
Published in Frontiers in physiology (27-04-2022)“…Circadian rhythms convergently evolved to allow for optimal synchronization of individuals' physiological and behavioral processes with the Earth's 24-h…”
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Chronic phase advances reduces recognition memory and increases vascular cognitive dementia-like impairments in aged mice
Published in Scientific reports (02-04-2024)“…Disrupted or atypical light–dark cycles disrupts synchronization of endogenous circadian clocks to the external environment; extensive circadian rhythm…”
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Chronotherapeutics for Solid Tumors
Published in Pharmaceutics (26-07-2023)“…Circadian rhythms are internal manifestations of the 24-h solar day that allow for synchronization of biological and behavioral processes to the external solar…”
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