Search Results - "Walker, Zuzana"
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Lewy body dementias
Published in The Lancet (British edition) (24-10-2015)“…Summary The broad importance of dementia is undisputed, with Alzheimer's disease justifiably getting the most attention. However, dementia with Lewy bodies and…”
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Late onset depression: dopaminergic deficit and clinical features of prodromal Parkinson’s disease: a cross-sectional study
Published in Journal of neurology, neurosurgery and psychiatry (01-02-2021)“…BackgroundLate onset depression (LOD) may precede the diagnosis of Parkinson’s disease (PD) or dementia with Lewy bodies (DLB). We aimed to determine the rate…”
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Clinical utility of FDG-PET for the clinical diagnosis in MCI
Published in European journal of nuclear medicine and molecular imaging (01-07-2018)“…Purpose We aim to report the quality of accuracy studies investigating the utility of [ 18 F]fluorodeoxyglucose (FDG)-PET in supporting the diagnosis of…”
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Are cholinesterase inhibitors effective in the management of the behavioral and psychological symptoms of dementia in Alzheimer's disease? A systematic review of randomized, placebo-controlled trials of donepezil, rivastigmine and galantamine
Published in International psychogeriatrics (01-10-2009)“…The study aim was to conduct a systematic review of the evidence from randomized, placebo controlled trials related to the efficacy of donepezil, rivastigmine…”
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START (STrAtegies for RelaTives) study: a pragmatic randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of a manual-based coping strategy programme in promoting the mental health of carers of people with dementia
Published in Health technology assessment (Winchester, England) (01-10-2014)“…Two-thirds of people with dementia live at home, receiving most care from family carers, about 40% of whom have clinically significant depression or anxiety…”
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Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial
Published in Lancet neurology (01-07-2009)“…Summary Background Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are common forms of dementia that substantially affect quality of…”
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Efficacy of lifestyle and psychosocial interventions in reducing cognitive decline in older people: Systematic review
Published in Ageing research reviews (01-09-2020)“…[Display omitted] •We review interventions to reduce cognitive decline.•We include studies in people without dementia, aged 50+ or with cognitive…”
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The criteria used to rule out mild cognitive impairment impact dementia incidence rates in subjective cognitive decline
Published in Alzheimer's research & therapy (28-06-2024)“…The research criteria for subjective cognitive decline (SCD) exclude mild cognitive impairment (MCI), but do not stipulate the use of specific MCI criteria…”
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Dementia diagnostic criteria in Down syndrome
Published in International journal of geriatric psychiatry (01-08-2015)“…Objective Dementia is a common clinical presentation among older adults with Down syndrome. The presentation of dementia in Down syndrome differs compared with…”
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Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia
Published in European journal of nuclear medicine and molecular imaging (01-07-2018)“…Purpose A joint effort of the European Association of Nuclear Medicine (EANM) and the European Academy of Neurology (EAN) aims at clinical guidance for the use…”
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Crop filling: A pipeline for repairing memory clinic MRI corrupted by partial brain coverage
Published in MethodsX (01-06-2024)“…Data-driven solutions offer great promise for improving healthcare. However, standard clinical neuroimaging data is subject to real-world imaging artefacts…”
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Clinical and cost-effectiveness of DREAMS START (Dementia RElAted Manual for Sleep; STrAtegies for RelaTives) for people living with dementia and their carers: a study protocol for a parallel multicentre randomised controlled trial
Published in BMJ open (01-02-2024)“…IntroductionMany people living with dementia experience sleep disturbance and there are no known effective treatments. Non-pharmacological treatment options…”
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Memory decline in Down syndrome and its relationship to iPF2alpha, a urinary marker of oxidative stress
Published in PloS one (05-06-2014)“…Lipid peroxidation may be a marker of free-radical-mediated injury associated with Alzheimer's disease (AD). We aimed to investigate whether changes in lipid…”
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Long-term clinical and cost-effectiveness of psychological intervention for family carers of people with dementia: a single-blind, randomised, controlled trial
Published in The Lancet. Psychiatry (01-12-2014)“…Summary Background Two-thirds of people with dementia live at home supported mainly by family carers. These carers frequently develop clinical depression or…”
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The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact
Published in Frontiers in neurology (20-01-2023)“…Amyloid-β (Aβ) accumulation is considered the earliest pathological change in Alzheimer's disease (AD). The Amyloid Imaging to Prevent Alzheimer's Disease…”
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Long-term outcome of depressive pseudodementia in the elderly
Published in Journal of affective disorders (01-08-2007)“…Abstract Background The term depressive pseudodementia has proved to be a popular clinical concept. Little is known about the long-term outcome of this…”
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Investigating the effects of impairment in non‐verbal communication on neuropsychiatric symptoms and quality of life of people living with dementia
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)“…Introduction People living with dementia in nursing homes have complex needs; impairments in cognition, communication, and daily function; neuropsychiatric…”
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Islington study of dementia subtypes in the community
Published in British journal of psychiatry (01-03-2002)“…Epidemiological studies of dementia subtypes have revealed widely varying distribution rates. There are almost no published community prevalence data for…”
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Analyzing large Alzheimer's disease cognitive datasets: Considerations and challenges
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)“…Recent data‐sharing initiatives of clinical and preclinical Alzheimer's disease (AD) have led to a growing number of non‐clinical researchers analyzing these…”
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Safety analysis of 10 clinical trials and for 13 years after first approval of ioflupane 123I injection (DaTscan)
Published in The Journal of nuclear medicine (1978) (01-08-2014)“…Ioflupane is an analog of cocaine that binds reversibly with high affinity to the dopamine transporter (DaT) protein, a marker for presynaptic terminals in…”
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