Search Results - "Walker, Michael F"

De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder by Dong, Shan, Walker, Michael F, Carriero, Nicholas J, DiCola, Michael, Willsey, A Jeremy, Ye, Adam Y, Waqar, Zainulabedin, Gonzalez, Luis E, Overton, John D, Frahm, Stephanie, Keaney, 3rd, John F, Teran, Nicole A, Dea, Jeanselle, Mandell, Jeffrey D, Hus Bal, Vanessa, Sullivan, Catherine A, DiLullo, Nicholas M, Khalil, Rehab O, Gockley, Jake, Yuksel, Zafer, Sertel, Sinem M, Ercan-Sencicek, A Gulhan, Gupta, Abha R, Mane, Shrikant M, Sheldon, Michael, Brooks, Andrew I, Roeder, Kathryn, Devlin, Bernie, State, Matthew W, Wei, Liping, Sanders, Stephan J

“…Whole-exome sequencing (WES) studies have demonstrated the contribution of de novo loss-of-function single-nucleotide variants (SNVs) to autism spectrum…”
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No evidence for association of autism with rare heterozygous point mutations in Contactin-Associated Protein-Like 2 (CNTNAP2), or in Other Contactin-Associated Proteins or Contactins by Murdoch, John D, Gupta, Abha R, Sanders, Stephan J, Walker, Michael F, Keaney, John, Fernandez, Thomas V, Murtha, Michael T, Anyanwu, Samuel, Ober, Gordon T, Raubeson, Melanie J, DiLullo, Nicholas M, Villa, Natalie, Waqar, Zainabdul, Sullivan, Catherine, Gonzalez, Luis, Willsey, A Jeremy, Choe, So-Yeon, Neale, Benjamin M, Daly, Mark J, State, Matthew W

“…Contactins and Contactin-Associated Proteins, and Contactin-Associated Protein-Like 2 (CNTNAP2) in particular, have been widely cited as autism risk genes…”
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Neurogenetic analysis of childhood disintegrative disorder by Gupta, Abha R, Westphal, Alexander, Yang, Daniel Y J, Sullivan, Catherine A W, Eilbott, Jeffrey, Zaidi, Samir, Voos, Avery, Vander Wyk, Brent C, Ventola, Pam, Waqar, Zainulabedin, Fernandez, Thomas V, Ercan-Sencicek, A Gulhan, Walker, Michael F, Choi, Murim, Schneider, Allison, Hedderly, Tammy, Baird, Gillian, Friedman, Hannah, Cordeaux, Cara, Ristow, Alexandra, Shic, Frederick, Volkmar, Fred R, Pelphrey, Kevin A

“…Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression…”
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De novo mutations revealed by whole-exome sequencing are strongly associated with autism by Sanders, Stephan J., Murtha, Michael T., Gupta, Abha R., Murdoch, John D., Raubeson, Melanie J., Willsey, A. Jeremy, Ercan-Sencicek, A. Gulhan, DiLullo, Nicholas M., Parikshak, Neelroop N., Stein, Jason L., Walker, Michael F., Ober, Gordon T., Teran, Nicole A., Song, Youeun, El-Fishawy, Paul, Murtha, Ryan C., Choi, Murim, Overton, John D., Bjornson, Robert D., Carriero, Nicholas J., Meyer, Kyle A., Bilguvar, Kaya, Mane, Shrikant M., Šestan, Nenad, Lifton, Richard P., Günel, Murat, Roeder, Kathryn, Geschwind, Daniel H., Devlin, Bernie, State, Matthew W.

“…Rare de novo single nucleotide variants in brain-expressed genes are found to be associated with autism spectrum disorders and to carry large effects…”
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In Vitro Cultivation of Microphallus turgidus (Trematoda: Microphallidae) from Metacercaria to Ovigerous Adult with Continuation of the Life Cycle in the Laboratory by Pung, Oscar J, Burger, Ashley R, Walker, Michael F, Barfield, Whitney L, Lancaster, Micah H, Jarrous, Christina E

“…In vitro cultivation of trematodes would aid studies on the basic biology of the parasites and the development of chemotherapies and vaccines. Our goal was to…”
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Facing Current Conditions: Employing Voting Rights Act Preclearance to Protect Reproductive Rights by Walker, Michael F

“…Since the Supreme Court's decision in Roe v. Wade in 1973, many states have passed various anti-abortion legislation that will likely curtail the right to…”
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The contribution of de novo coding mutations to autism spectrum disorder by Iossifov, Ivan, O’Roak, Brian J., Sanders, Stephan J., Ronemus, Michael, Krumm, Niklas, Levy, Dan, Stessman, Holly A., Witherspoon, Kali T., Vives, Laura, Patterson, Karynne E., Smith, Joshua D., Paeper, Bryan, Nickerson, Deborah A., Dea, Jeanselle, Dong, Shan, Gonzalez, Luis E., Mandell, Jeffrey D., Mane, Shrikant M., Murtha, Michael T., Sullivan, Catherine A., Walker, Michael F., Waqar, Zainulabedin, Wei, Liping, Willsey, A. Jeremy, Yamrom, Boris, Lee, Yoon-ha, Grabowska, Ewa, Dalkic, Ertugrul, Wang, Zihua, Marks, Steven, Andrews, Peter, Leotta, Anthony, Kendall, Jude, Hakker, Inessa, Rosenbaum, Julie, Ma, Beicong, Rodgers, Linda, Troge, Jennifer, Narzisi, Giuseppe, Yoon, Seungtai, Schatz, Michael C., Ye, Kenny, McCombie, W. Richard, Shendure, Jay, Eichler, Evan E., State, Matthew W., Wigler, Michael

“…Whole exome sequencing has proven to be a powerful tool for understanding the genetic architecture of human disease. Here we apply it to more than 2,500…”
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Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci by Sanders, Stephan J., He, Xin, Willsey, A. Jeremy, Ercan-Sencicek, A. Gulhan, Samocha, Kaitlin E., Cicek, A. Ercument, Murtha, Michael T., Bal, Vanessa H., Bishop, Somer L., Dong, Shan, Goldberg, Arthur P., Jinlu, Cai, Keaney, John F., Klei, Lambertus, Mandell, Jeffrey D., Moreno-De-Luca, Daniel, Poultney, Christopher S., Robinson, Elise B., Smith, Louw, Solli-Nowlan, Tor, Su, Mack Y., Teran, Nicole A., Walker, Michael F., Werling, Donna M., Beaudet, Arthur L., Cantor, Rita M., Fombonne, Eric, Geschwind, Daniel H., Grice, Dorothy E., Lord, Catherine, Lowe, Jennifer K., Mane, Shrikant M., Martin, Donna M., Morrow, Eric M., Talkowski, Michael E., Sutcliffe, James S., Walsh, Christopher A., Yu, Timothy W., Ledbetter, David H., Martin, Christa Lese, Cook, Edwin H., Buxbaum, Joseph D., Daly, Mark J., Devlin, Bernie, Roeder, Kathryn, State, Matthew W.

“…Analysis of de novo CNVs (dnCNVs) from the full Simons Simplex Collection (SSC) (N = 2,591 families) replicates prior findings of strong association with…”
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An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder by Werling, Donna M., Brand, Harrison, An, Joon-Yong, Stone, Matthew R., Zhu, Lingxue, Glessner, Joseph T., Collins, Ryan L., Dong, Shan, Layer, Ryan M., Markenscoff-Papadimitriou, Eirene, Farrell, Andrew, Schwartz, Grace B., Wang, Harold Z., Currall, Benjamin B., Zhao, Xuefang, Dea, Jeanselle, Duhn, Clif, Erdman, Carolyn A., Gilson, Michael C., Yadav, Rachita, Handsaker, Robert E., Kashin, Seva, Klei, Lambertus, Mandell, Jeffrey D., Nowakowski, Tomasz J., Liu, Yuwen, Pochareddy, Sirisha, Smith, Louw, Walker, Michael F., Waterman, Matthew J., He, Xin, Kriegstein, Arnold R., Rubenstein, John L., Sestan, Nenad, McCarroll, Steven A., Neale, Benjamin M., Coon, Hilary, Willsey, A. Jeremy, Buxbaum, Joseph D., Daly, Mark J., State, Matthew W., Quinlan, Aaron R., Marth, Gabor T., Roeder, Kathryn, Devlin, Bernie, Talkowski, Michael E., Sanders, Stephan J.

“…Genomic association studies of common or rare protein-coding variation have established robust statistical approaches to account for multiple testing. Here we…”
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De Novo Coding Variants Are Strongly Associated with Tourette Disorder by Willsey, A. Jeremy, Yu, Dongmei, King, Robert A., Dietrich, Andrea, Xing, Jinchuan, Richer, Petra, Smith, Louw, Dong, Shan, Samocha, Kaitlin E., Bohnenpoll, Julia, Bromberg, Yana, Brown, Lawrence W., Cheon, Keun-Ah, Coffey, Barbara J., Deng, Li, Dong, Shan, Elzerman, Lonneke, Fernandez, Thomas V., Fründt, Odette, Garcia-Delgar, Blanca, Gedvilaite, Erika, Grice, Dorothy E., Hagstrøm, Julie, Hedderly, Tammy, Heiman, Gary A., Heyman, Isobel, Hoekstra, Pieter J., Hong, Hyun Ju, Ibanez-Gomez, Laura, Kim, Young Key, Kim, Young-Shin, King, Robert A., Koh, Yun-Joo, Kook, Sodahm, Kuperman, Samuel, Lamerz, Andreas, Ludolph, Andrea G., Lühr da Silva, Claudia, Madruga-Garrido, Marcos, Mir, Pablo, Münchau, Alexander, Murphy, Tara L., Nasello, Cara, Openneer, Thaïra J.C., Plessen, Kerstin J., Richer, Petra, Roessner, Veit, Sanders, Stephan, Smith, Louw, Song, Dong-Ho, State, Matthew W., Stolte, Anne Marie, Sun, Nawei, Tischfield, Jay A., Tübing, Jennifer, Visscher, Frank, Walker, Michael F., Wanderer, Sina, Wang, Shuoguo, Willsey, A. Jeremy, Woods, Martin, Xing, Jinchuan, Zhang, Yeting, Zhou, Anbo, Zinner, Samuel H., Batterson, James R., Berlin, Cheston, Bruun, Ruth D., Budman, Cathy L., Cath, Danielle C., Chouinard, Sylvain, Coppola, Giovanni, Cox, Nancy J., Darrow, Sabrina, Davis, Lea K., Freimer, Nelson B., Grados, Marco A., Hirschtritt, Matthew E., Illmann, Cornelia, Kurlan, Roger, Lyon, Gholson J., Malaty, Irene A., Mathews, Carol A., Neale, Benjamin M., Okun, Michael S., Osiecki, Lisa, Posthuma, Danielle, Ramensky, Vasily, Robertson, Mary M., Rouleau, Guy A., Sandor, Paul, Singer, Harvey S., Yu, Dongmei, Neale, Benjamin M., Coppola, Giovanni, Mathews, Carol A., Tischfield, Jay A., Scharf, Jeremiah M., State, Matthew W., Heiman, Gary A.

“…Whole-exome sequencing (WES) and de novo variant detection have proven a powerful approach to gene discovery in complex neurodevelopmental disorders. We have…”
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Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons by Griesi-Oliveira, K, Acab, A, Gupta, A R, Sunaga, D Y, Chailangkarn, T, Nicol, X, Nunez, Y, Walker, M F, Murdoch, J D, Sanders, S J, Fernandez, T V, Ji, W, Lifton, R P, Vadasz, E, Dietrich, A, Pradhan, D, Song, H, Ming, G-l, Gu, X, Haddad, G, Marchetto, M C N, Spitzer, N, Passos-Bueno, M R, State, M W, Muotri, A R

“…An increasing number of genetic variants have been implicated in autism spectrum disorders (ASDs), and the functional study of such variants will be critical…”
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Allantoin as A Biomarker of Inflammation in an Inflammatory Bowel Disease Mouse Model: NMR Analysis of Urine by Dryland, Philippa A., Love, Donald R., Walker, Michael F., Dommels, Yvonne, Butts, Christine, Rowan, Daryl, Roy, Nicole C., Helsby, Nuala, Browning, Brian L., Zhu, Shuotun, Copp, Brent R., Ferguson, Lynnette R.

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No evidence for association of Autism with rare heterozygous point mutations in contactin-associated protein-like 2 by Murdoch, John D, Gupta, Abha R, Sanders, Stephan J, Walker, Michael F, Keaney, John, Fernandez, Thomas V, Murtha, Michael T, Anyanwu, Samuel, Ober, Gordon T, Raubeson, Melanie J, DiLullo, Nicholas M, Villa, Natalie, Waqar, Zainabdul, Sullivan, Catherine, Gonzalez, Luis, Willsey, A. Jeremy, Choe, So-Yeon, Neale, Benjamin M, Daly, Mark J, State, Matthew W

“…Contactins and Contactin-Associated Proteins, and Contactin-Associated Protein-Like 2 (CNTNAP2) in particular, have been widely cited as autism risk genes…”
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No Evidence for Association of Autism with Rare Heterozygous Point Mutations in Contactin-Associated Protein-Like 2 ( CNTNAP2 ), or in Other Contactin-Associated Proteins or Contactins: e1004852 by Murdoch, John D, Gupta, Abha R, Sanders, Stephan J, Walker, Michael F, Keaney, John, Fernandez, Thomas V, Murtha, Michael T, Anyanwu, Samuel, Ober, Gordon T, Raubeson, Melanie J, DiLullo, Nicholas M, Villa, Natalie, Waqar, Zainabdul, Sullivan, Catherine, Gonzalez, Luis, Willsey, A Jeremy, Choe, So-Yeon, Neale, Benjamin M, Daly, Mark J, State, Matthew W

“…Contactins and Contactin-Associated Proteins, and Contactin-Associated Protein-Like 2 (CNTNAP2) in particular, have been widely cited as autism risk genes…”
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Recovering addiction: A critique of intoxicant governance in the United States by Walker, Michael F

“…This dissertation explores the historical development and contemporary deployment of discursive practices that constitute the “truth” of addiction, which in…”
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Animal Model of Isolated Gonadotropin Deficiency I. Hormonal Responses to LHRH Immunoneutralization by SCHANBACHER, BRUCE D., ENGLISH, HUGH F., GROSS, DOUGLAS, SANTEN, RICHARD J., WALKER, MICHAEL F., FALVO, RICHARD E.

“…Five intact male mongrel dogs, characterized by an episodic secretory pattern of LH and normal serum testosterone concentrations, were actively immunized…”
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Animal model of isolated gonadotropin deficiency. II. Morphologic responses to LHRH immunoneutralization by English, H. F, Schanbacher, B. D, Gross, D, Walker, M. F, Falvo, R. E, Santen, R. J

“…Morphologic changes in the male reproductive system of mongrel dogs immunized against LHRH were quantitated using linear measurements and morphometric…”
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