Search Results - "Walker, Marjorie M"

Novel concepts in the pathophysiology and treatment of functional dyspepsia by Wauters, Lucas, Talley, Nicholas J, Walker, Marjorie M, Tack, Jan, Vanuytsel, Tim

“…Emerging data increasingly point towards the duodenum as a key region underlying the pathophysiology of functional dyspepsia (FD), one of the most prevalent…”
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Nerve-Cancer Cell Cross-talk: A Novel Promoter of Tumor Progression by Jobling, Phillip, Pundavela, Jay, Oliveira, Sonia M R, Roselli, Séverine, Walker, Marjorie M, Hondermarck, Hubert

“…Recent studies have revealed the essential role played by nerves in tumor progression. Nerves have been shown to infiltrate the tumor microenvironment and…”
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Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Case-Control Studies by Shah, Ayesha, Talley, Nicholas J., Jones, Mike, Kendall, Bradley J., Koloski, Natasha, Walker, Marjorie M., Morrison, Mark, Holtmann, Gerald J.

“…We conducted a systematic review and meta-analysis to compare the prevalence of small intestinal bacterial overgrowth (SIBO) in patients with irritable bowel…”
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Evidence for Local and Systemic Immune Activation in Functional Dyspepsia and the Irritable Bowel Syndrome: A Systematic Review by Burns, Grace, Carroll, Georgia, Mathe, Andrea, Horvat, Jay, Foster, Paul, Walker, Marjorie M, Talley, Nicholas J, Keely, Simon

“…Subtle histopathologic features such as eosinophilia and increased mast cells have been observed in functional gastrointestinal disorders (FGIDs), including…”
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Small Intestinal Bacterial Overgrowth in Functional Dyspepsia: A Systematic Review and Meta-Analysis by Gurusamy, Saravana Ruban, Shah, Ayesha, Talley, Nicholas J., Koloski, Natasha, Jones, Michael P., Walker, Marjorie M., Morrison, Mark, Holtmann, Gerald

“…This systematic review and meta-analysis aimed to determine the role of small intestinal bacterial overgrowth (SIBO) in patients with functional dyspepsia…”
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The Role of Duodenal Inflammation in Functional Dyspepsia by Walker, Marjorie M, Talley, Nicholas J

“…Functional dyspepsia (FD) is common and significantly impairs quality of life. Symptoms of FD are considered to originate from the gastroduodenal region,…”
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Therapeutic strategies for functional dyspepsia and irritable bowel syndrome based on pathophysiology by Talley, Nicholas J., Holtmann, Gerald, Walker, Marjorie M.

“…Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so named because a defined pathophysiology in terms of structural or…”
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Understanding the value of brain donation for research to donors, next-of-kin and clinicians: A systematic review by Griffin, Cassandra P, Bowen, Jenna R, Walker, Marjorie M, Lynam, James, Paul, Christine L

“…Post-mortem brain donation affords the opportunity to characterise disease by exploring global neuropathological changes. Such opportunities are essential to…”
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Duodenal eosinophilia and early satiety in functional dyspepsia: Confirmation of a positive association in an Australian cohort by Walker, Marjorie M, Aggarwal, Kavita R, Shim, Lisa SE, Bassan, Milan, Kalantar, Jamshid S, Weltman, Martin D, Jones, Michael, Powell, Nicholas, Talley, Nicholas J

“…Background and Aim Functional dyspepsia (FD), defined by unexplained pain or discomfort centered in the upper abdomen, is common. Diagnosis and treatment of FD…”
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Current status and advances in esophageal drug delivery technology: influence of physiological, pathophysiological and pharmaceutical factors by Lim, Ai Wei, Talley, Nicholas J., Walker, Marjorie M., Storm, Gert, Hua, Susan

“…Diseases affecting the esophagus are common. However, targeted drug delivery to the esophagus is challenging due to the anatomy and physiology of this organ…”
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Influence of cigarette smoking on the human duodenal mucosa-associated microbiota by Shanahan, Erin R, Shah, Ayesha, Koloski, Natasha, Walker, Marjorie M, Talley, Nicholas J, Morrison, Mark, Holtmann, Gerald J

“…Cigarette smoking is a known risk factor in a number of gastrointestinal (GI) diseases in which the microbiota is implicated, including duodenal ulcer and…”
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Iron status and Helicobacter pylori infection in symptomatic children: an international multi-centered study by Queiroz, Dulciene Maria Magalhaes, Harris, Paul R, Sanderson, Ian R, Windle, Henry J, Walker, Marjorie M, Rocha, Andreia Maria Camargos, Rocha, Gifone Aguiar, Carvalho, Simone Diniz, Bittencourt, Paulo Fernando Souto, de Castro, Lucia Porto Fonseca, Villagrán, Andrea, Serrano, Carolina, Kelleher, Dermot, Crabtree, Jean E

“…Iron deficiency (ID) and iron deficiency anaemia (IDA) are global major public health problems, particularly in developing countries. Whilst an association…”
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Wheat Sensitivity and Functional Dyspepsia: A Pilot, Double-Blind, Randomized, Placebo-Controlled Dietary Crossover Trial with Novel Challenge Protocol by Potter, Michael D E, Duncanson, Kerith, Jones, Michael P, Walker, Marjorie M, Keely, Simon, Talley, Nicholas J

“…Functional dyspepsia (FD), characterised by symptoms of epigastric pain or early satiety and post prandial distress, has been associated with duodenal…”
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Non-ulcer Dyspepsia and Duodenal Eosinophilia: An Adult Endoscopic Population-Based Case-Control Study by Talley, Nicholas J, Walker, Marjorie M, Aro, Pertti, Ronkainen, Jukka, Storskrubb, Tom, Hindley, Laura A, Harmsen, W. Scott, Zinsmeister, Alan R, Agréus, Lars

“…Background & Aims: Functional abnormalities of the duodenum have been observed in non-ulcer dyspepsia. We aimed to identify whether eosinophils in the upper…”
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Gastrointestinal eosinophils in health, disease and functional disorders by Talley, Nicholas J, Powell, Nicholas, Walker, Marjorie M

“…Eosinophils are potent innate immune cells that are numerous in the gastrointestinal tract in health and disease. This Review discusses the role of eosinophils…”
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The duodenal mucosa associated microbiome, visceral sensory function, immune activation and psychological comorbidities in functional gastrointestinal disorders with and without self-reported non-celiac wheat sensitivity by Shah, Ayesha, Kang, Seungha, Talley, Nicholas J, Do, Anh, Walker, Marjorie M, Shanahan, Erin R, Koloski, Natasha A, Jones, Michael P, Keely, Simon, Morrison, Mark, Holtmann, Gerald J

“…Frequently, patients with functional gastrointestinal disorders (FGIDs) report intolerance of wheat products. We compared gastrointestinal symptoms, sensory…”
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Mouse DNA contamination in human tissue tested for XMRV by Robinson, Mark J, Erlwein, Otto W, Kaye, Steve, Weber, Jonathan, Cingoz, Oya, Patel, Anup, Walker, Marjorie M, Kim, Wun-Jae, Uiprasertkul, Mongkol, Coffin, John M, McClure, Myra O

“…We used a PCR-based approach to study the prevalence of genetic sequences related to a gammaretrovirus, xenotropic murine leukemia virus-related virus, XMRV,…”
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Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia by Burns, Grace L, Bruce, Jessica K, Minahan, Kyra, Mathe, Andrea, Fairlie, Thomas, Cameron, Raquel, Naudin, Crystal, Nair, Prema M, Potter, Michael D E, Irani, Mudar Zand, Bollipo, Steven, Foster, Robert, Gan, Lay T, Shah, Ayesha, Koloski, Natasha A, Foster, Paul S, Horvat, Jay C, Veysey, Martin, Holtmann, Gerald, Powell, Nick, Walker, Marjorie M, Talley, Nicholas J, Keely, Simon

“…Functional dyspepsia is characterised by chronic symptoms of post-prandial distress or epigastric pain not associated with defined structural pathology…”
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Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden by Walker, Marjorie M., BMBS, FRCPath, Talley, Nicholas J., MD, PhD, Inganäs, Linn, MSc, Engstrand, Lars, MD, PhD, Jones, Michael P., PhD, Nyhlin, Henry, MD, PhD, Agréus, Lars, MD, PhD, Kjellstrom, Lars, MD, Öst, Åke, MD, PhD, Andreasson, Anna, PhD

“…Summary Irritable bowel syndrome (IBS) is a functional disorder defined by symptoms in the absence of overt pathology. Colonic spirochetosis (CS), defined by…”
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TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis by Collison, Adam M., PhD, Sokulsky, Leon A., BBiomedSci (Hons), Sherrill, Joseph D., PhD, Nightingale, Scott, BMed (Hons), MClinEpid, FRACP, Hatchwell, Luke, BBiomedSci (Hons), Talley, Nicholas J., MD, PhD, Walker, Marjorie M., FRCPath, Rothenberg, Marc E., MD, PhD, Mattes, Joerg, MD, PhD

“…Background Eosinophilic esophagitis (EoE) is an inflammatory disorder of the esophagus defined by eosinophil infiltration and tissue remodeling with resulting…”
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