Search Results - "Walker, L. S. K."

CD4 T cell differentiation in type 1 diabetes by Walker, L. S. K., von Herrath, M.

“…Summary Susceptibility to type 1 diabetes is associated strongly with human leucocyte antigen (HLA) genes, implicating T cells in disease pathogenesis. In…”
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Immune deficiency and autoimmunity in patients with CTLA‐4 (CD152) mutations by Verma, N., Burns, S. O., Walker, L. S. K., Sansom, D. M.

“…Summary Immune deficiency disorders are a heterogeneous group of diseases of variable genetic aetiology. While the hallmark of immunodeficiency is…”
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Lack of activation induced cell death in human T blasts despite CD95L
up‐regulation: protection from apoptosis by MEK signalling by Walker, L. S. K., Mcleod, J. D., Boulougouris, G., Patel, Y. I., Ellwood, C. N., Hall, N. D., Sansom, D. M.

“…Summary The generation of effective immunity requires that antigen‐specific T cells are activated, clonally expanded and ultimately eliminated by apoptosis…”
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Immune regulation and colitis: suppression of acute inflammation allows the development of chronic inflammatory bowel disease by Eksteen, B, Walker, L S K, Adams, D H

“…[...]it has been reported that Tregs express a membrane bound form of the TGF-β cytokine. 11 In addition to thymic Tregs, inducible Tregs can be generated in…”
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CD4+ T cell mediated intestinal immunity: chronic inflammation versus immune regulation. Commentary by WESTENDORF, A. M, TEMPLIN, M, BUER, J, EKSTEEN, B, WALKER, L. S. K, ADAMS, D. H, GEFFERS, R, DEPPENMEIER, S, GRUBER, A. D, PROBST-KEPPER, M, HANSEN, W, LIBLAU, R. S, GUNZER, F, BRUDER, D

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Lack of activation induced cell death in human T blast despite CD95L up-regulation: protection from apoptosis by MEK signalling by Walker, L S K, McLeod, J D, Boulougouris, G, Patel, Y I

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Down‐regulation of CD28 via Fas (CD95): influence of CD28 on T‐cell apoptosis by Walker, L S, McLeod, J D, Boulougouris, G, Patel, Y I, Hall, N D, Sansom, D M

“…Following antigen engagement of the T‐cell receptor (TCR), T‐cell survival is largely dictated by the provision of additional signals, such as those from…”
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Manipulation of the T cell immune system via CD28 and CTLA-4 by Sansom, D. M., Walker, L. S. K.

“…IntroductionIn order to provide protection from a vast array of infectious agents, the immune system has evolved a series of defences based on specialized…”
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