Search Results - "Walker, Jennifer N."

Urinary tract infections: epidemiology, mechanisms of infection and treatment options by Flores-Mireles, Ana L., Walker, Jennifer N., Caparon, Michael, Hultgren, Scott J.

“…Key Points Urinary tract infections (UTIs) are some of the most common bacterial infections and are caused by both Gram-negative and Gram-positive species…”
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Microbial co-occurrences on catheters from long-term catheterized patients by Nye, Taylor M., Zou, Zongsen, Obernuefemann, Chloe L. P., Pinkner, Jerome S., Lowry, Erin, Kleinschmidt, Kent, Bergeron, Karla, Klim, Aleksandra, Dodson, Karen W., Flores-Mireles, Ana L., Walker, Jennifer N., Wong, Daniel Garrett, Desai, Alana, Caparon, Michael G., Hultgren, Scott J.

“…Catheter-associated urinary tract infections (CAUTIs), a common cause of healthcare-associated infections, are caused by a diverse array of pathogens that are…”
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Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation by Almqvist, Fredrik, Chapman, Matthew R, Hultgren, Scott J, Cegelski, Lynette, Pinkner, Jerome S, Hammer, Neal D, Cusumano, Corinne K, Hung, Chia S, Chorell, Erik, Åberg, Veronica, Walker, Jennifer N, Seed, Patrick C

“…Curli are functional extracellular amyloid fibers produced by uropathogenic Escherichia coli (UPEC) and other Enterobacteriaceae. Ring-fused 2-pyridones, such…”
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Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli by Henderson, Jeffrey P, Crowley, Jan R, Pinkner, Jerome S, Walker, Jennifer N, Tsukayama, Pablo, Stamm, Walter E, Hooton, Thomas M, Hultgren, Scott J

“…Bacterial pathogens are frequently distinguished by the presence of acquired genes associated with iron acquisition. The presence of specific siderophore…”
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Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding by Chen, Swaine L, Hung, Chia S, Pinkner, Jerome S, Walker, Jennifer N, Cusumano, Corinne K, Li, Zhaoli, Bouckaert, Julie, Gordon, Jeffrey I, Hultgren, Scott J

“…FimH, the type 1 pilus adhesin of uropathogenic Escherichia coli (UPEC), contains a receptor-binding domain with an acidic binding pocket specific for mannose…”
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Semi-Quantitative Assay to Measure Urease Activity by Urinary Catheter-Associated Uropathogens by Duran Ramirez, Jesus M, Gomez, Jana, Obernuefemann, Chloe L P, Gualberto, Nathaniel C, Walker, Jennifer N

“…Catheter-associated urinary tract infections (CAUTIs) are one of the most common healthcare-associated infections in the US, accounting for over 1 million…”
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Antibody-Based Therapy for Enterococcal Catheter-Associated Urinary Tract Infections by Flores-Mireles, Ana L, Walker, Jennifer N, Potretzke, Aaron, Schreiber, 4th, Henry L, Pinkner, Jerome S, Bauman, Tyler M, Park, Alyssa M, Desai, Alana, Hultgren, Scott J, Caparon, Michael G

“…Gram-positive bacteria in the genus Enterococcus are a frequent cause of catheter-associated urinary tract infection (CAUTI), a disease whose treatment is…”
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Utilization of an Intracellular Bacterial Community Pathway in Klebsiella pneumoniae Urinary Tract Infection and the Effects of FimK on Type 1 Pilus Expression by Rosen, David A, Pinkner, Jerome S, Jones, Jennifer M, Walker, Jennifer N, Clegg, Steven, Hultgren, Scott J

“…Klebsiella pneumoniae is an important cause of urinary tract infection (UTI), but little is known about its pathogenesis in vivo. The pathogenesis of the K…”
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The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis by Walker, Jennifer N, Crosby, Heidi A, Spaulding, Adam R, Salgado-Pabón, Wilmara, Malone, Cheryl L, Rosenthal, Carolyn B, Schlievert, Patrick M, Boyd, Jeffrey M, Horswill, Alexander R

“…Staphylococcus aureus is a prominent bacterial pathogen that is known to agglutinate in the presence of human plasma to form stable clumps. There is increasing…”
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Defining the Roles of Pyruvate Oxidation, TCA Cycle, and Mannitol Metabolism in Methicillin-Resistant Staphylococcus aureus Catheter-Associated Urinary Tract Infection by Paudel, Santosh, Guedry, Sarah, Obernuefemann, Chloe L P, Hultgren, Scott J, Walker, Jennifer N, Kulkarni, Ritwij

“…Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of complicated urinary tract infection (UTI) associated with the use of indwelling…”
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Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection by Mysorekar, Indira U, Isaacson-Schmid, Megan, Walker, Jennifer N, Mills, Jason C, Hultgren, Scott J

“…The transitional epithelium of the bladder normally turns over slowly but upon injury undergoes rapid regeneration fueled by basal uroepithelial stem and/or…”
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In vitro antibacterial, antibiofilm activities, and phytochemical properties of Posidonia oceanica (L.) Delile: An endemic Mediterranean seagrass by Ozbil, Ertugrul, Ilktac, Mehmet, Ogmen, Sultan, Isbilen, Ovgu, Duran Ramirez, Jesus M., Gomez, Jana, Walker, Jennifer N., Volkan, Ender

“…In the antibiotic resistance era, utilizing understudied sources for novel antimicrobials or antivirulence agents can provide new advances against…”
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Staphylococcus aureus Breast Implant Infection Isolates Display Recalcitrance To Antibiotic Pocket Irrigants by Duran Ramirez, Jesus M, Gomez, Jana, Hanson, Blake M, Isa, Taha, Myckatyn, Terence M, Walker, Jennifer N

“…Breast implant-associated infections (BIAIs) are the primary complication following placement of breast prostheses in breast cancer reconstruction. Given the…”
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A prospective randomized clinical trial to assess antibiotic pocket irrigation on tissue expander breast reconstruction by Walker, Jennifer N., Hanson, Blake M., Hunter, Tayler, Simar, Shelby R., Duran Ramirez, Jesus M., Obernuefemann, Chloe L. P., Parikh, Rajiv P., Tenenbaum, Marissa M., Margenthaler, Julie A., Hultgren, Scott J., Myckatyn, Terence M.

“…ABSTRACT Bacterial infection is the most common complication following staged post-mastectomy breast reconstruction initiated with a tissue expander (TE). To…”
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Molecular Variations in Klebsiella pneumoniae and Escherichia coli FimH Affect Function and Pathogenesis in the Urinary Tract by Rosen, David A, Pinkner, Jerome S, Walker, Jennifer N, Elam, Jennifer Stine, Jones, Jennifer M, Hultgren, Scott J

“…Type 1 pili mediate binding, invasion, and biofilm formation of uropathogenic Escherichia coli (UPEC) in the host urothelium during urinary tract infection…”
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A coverslip-based technique for evaluating Staphylococcus aureus biofilm formation on human plasma by Walker, Jennifer N, Horswill, Alexander R

“…The ability of the opportunistic pathogen, Staphylococcus aureus, to form biofilms is increasingly being viewed as an important contributor to chronic…”
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The Detection of Bacteria and Matrix Proteins on Clinically Benign and Pathologic Implants by Walker, Jennifer N., Pinkner, Chloe L., Pinkner, Jerome S., Hultgren, Scott J., Myckatyn, Terence M.

“…BACKGROUND:Bacterial contamination of breast implants causes infection, can lead to capsular contracture, and is implicated in breast implant-associated…”
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Commentary on: Biofilm Formation on Breast Implant Surfaces by Major Gram-Positive Bacterial Pathogens by Walker, Jennifer N, Myckatyn, Terence

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Insights into the Microbiome of Breast Implants and Periprosthetic Tissue in Breast Implant-Associated Anaplastic Large Cell Lymphoma by Walker, Jennifer N., Hanson, Blake M., Pinkner, Chloe L., Simar, Shelby R., Pinkner, Jerome S., Parikh, Rajiv, Clemens, Mark W., Hultgren, Scott J., Myckatyn, Terence M.

“…Though rare, breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a CD30+ T-cell lymphoma associated with textured breast implants, has…”
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Discussion: Doxycycline-Coated Silicone Breast Implants Reduce Acute Surgical-Site Infection and Inflammation by Walker, Jennifer N., Myckatyn, Terence M.

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