Search Results - "Walker, J. N."

Th17 Pathway As a Target for Multipotent Stromal Cell Therapy in Dogs: Implications for Translational Research by Kol, A, Walker, N J, Nordstrom, M, Borjesson, D L

“…Detrimental Th17 driven inflammatory and autoimmune disease such as Crohn's disease, graft versus host disease and multiple sclerosis remain a significant…”
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Regulation of glucagon secretion by glucose: paracrine, intrinsic or both? by Walker, J. N., Ramracheya, R., Zhang, Q., Johnson, P. R. V., Braun, M., Rorsman, P.

“…Glucagon secretion is regulated by glucose but the mechanisms involved remain hotly debated. Both intrinsic (within the α‐cell itself) and paracrine (mediated…”
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Gender difference and effect of pharmacotherapy: findings from a smoking cessation service by Walker, N J, van Woerden, H C, Kiparoglou, V, Yang, Y, Robinson, H, Croghan, E

“…Smoking cessation services are available in England to provide assistance to those wishing to quit smoking. Data from one such service were analysed in order…”
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A thyroxine absorption test followed by weekly thyroxine administration: a method to assess non-adherence to treatment by Walker, J N, Shillo, P, Ibbotson, V, Vincent, A, Karavitaki, N, Weetman, A P, Wass, J A H, Allahabadia, A

“…ObjectiveFor patients who remain hypothyroid despite the administration of what would seem adequate doses of levothyroxine (l-T4), the underlying cause can be…”
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Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study by Budinsky, R. A., Schrenk, D., Simon, T., Van den Berg, M., Reichard, J. F., Silkworth, J. B., Aylward, L. L., Brix, A., Gasiewicz, T., Kaminski, N., Perdew, G., Starr, T. B., Walker, N. J., Rowlands, J. C.

“…Abstract Dioxins and dioxin-like compounds are tumor promoters that cause liver cancer in rats and mice. The aryl hydrocarbon receptor (AHR) has been…”
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Social organization and movement influence the incidence of bovine tuberculosis in an undisturbed high-density badger Meles meles population by VICENTE, J, DELAHAY, R.J, WALKER, N.J, CHEESEMAN, C.L

“…1. The culling of European badgers Meles meles has been a central part of attempts to control bovine tuberculosis (TB) in British cattle for many years. Recent…”
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Climate change impacts on agro-ecosystem sustainability across three climate regions in the maize belt of South Africa by Walker, N.J., Schulze, R.E.

“…The Highveld region in South Africa is an important area for its food production for the nation, as 70% of country's cereal crops and 90% of the commercially…”
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Infection with Anaplasma phagocytophilum Induces Multilineage Alterations in Hematopoietic Progenitor Cells and Peripheral Blood Cells by Johns, J.L, MacNamara, K.C, Walker, N.J, Winslow, G.M, Borjesson, D.L

“…Infection with Anaplasma phagocytophilum, a gram-negative, lipopolysaccharide (LPS)-negative, obligate intracellular bacterium, results in multiple peripheral…”
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Erratum to: Gender difference and effect of pharmacotherapy: findings from a smoking cessation service by Walker, N J, van Woerden, H C, Kiparoglou, V, Yang, Y, Robinson, H, Croghan, E

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Immunogenicity of Recombinant Protective Antigen and Efficacy against Aerosol Challenge with Anthrax by Williamson, E. D, Hodgson, I, Walker, N. J, Topping, A. W, Duchars, M. G, Mott, J. M, Estep, J, LeButt, C, Flick-Smith, H. C, Jones, H. E, Li, H, Quinn, C. P

“…Immunization with a recombinant form of the protective antigen (rPA) from Bacillus anthracis has been carried out with rhesus macaques. Rhesus macaques…”
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Identifying seasonal and temporal trends in the pressures experienced by hospitals related to unscheduled care by Walker, N J, Van Woerden, H C, Kiparoglou, V, Yang, Y

“…As part of an electronic dashboard operated by Public Health Wales, senior managers at hospitals in Wales report daily "escalation" scores which reflect…”
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effects of therapeutic concentrations of gentamicin, amikacin and hyaluronic acid on cultured bone marrow‐derived equine mesenchymal stem cells by Bohannon, L. K, Owens, S. D, Walker, N. J, Carrade, D. D, Galuppo, L. D, Borjesson, D. L

“…REASONS FOR PERFORMING STUDY: Joint inflammation and septic arthritis are both potential complications of intra‐articular injections of bone marrow‐derived…”
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Autologous point-of-care cellular therapies variably induce equine mesenchymal stem cell migration, proliferation and cytokine expression by KOL, A., WALKER, N. J., GALUPPO, L. D., CLARK, K. C., BUERCHLER, S., BERNANKE, A., BORJESSON, D. L.

“…Summary Reasons for performing study: Autologous cellular therapy products including adipose‐derived stromal vascular fraction (SVF), bone marrow mononuclear…”
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Glucose-responsive beta cells in islets isolated from a patient with long-standing type 1 diabetes mellitus by Walker, J. N., Johnson, P. R. V., Shigeto, M., Hughes, S. J., Clark, A., Rorsman, P.

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The role of interventional radiology and imaging in pancreatic islet cell transplantation by Dixon, S, Tapping, C.R, Walker, J.N, Bratby, M, Anthony, S, Boardman, P, Phillips-Hughes, J, Uberoi, R

“…Pancreatic islet cell transplantation (PICT) is a novel treatment for patients with insulin-dependent diabetes who have inadequate glycaemic control or…”
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A new, theoretically safer method of intravitreal injection of bevacizumab in progressive retinopathy of prematurity using scleral trans-illumination by Patel, C K, Walker, N J, Kam, J K

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17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1 by Hayes, C L, Spink, D C, Spink, B C, Cao, J Q, Walker, N J, Sutter, T R

“…The 4-hydroxy metabolite of 17 beta-estradiol (E2) has been implicated in the carcinogenicity of this hormone. Previous studies showed that aryl…”
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Demographic correlates of bite wounding in Eurasian badgers, Meles meles L., in stable and perturbed populations by Delahay, R.J., Walker, N.J., Forrester, G.J., Harmsen, B., Riordan, P., Macdonald, D.W., Newman, C., Cheeseman, C.L.

“…In the U.K., Eurasian badgers often live in social groups and defend a collective territory. Aggressive encounters between badgers may lead to bite wounds,…”
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Use of bioengineered human commensal gut bacteria‐derived microvesicles for mucosal plague vaccine delivery and immunization by Carvalho, A. L., Miquel‐Clopés, A., Wegmann, U., Jones, E., Stentz, R., Telatin, A., Walker, N. J., Butcher, W. A., Brown, P. J., Holmes, S., Dennis, M. J., Williamson, E. D., Funnell, S. G. P., Stock, M., Carding, S. R.

“…Summary Plague caused by the Gram‐negative bacterium, Yersinia pestis, is still endemic in parts of the world today. Protection against pneumonic plague is…”
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Longevity of human islet α- and β-cells by Cnop, M., Igoillo-Esteve, M., Hughes, S. J., Walker, J. N., Cnop, I., Clark, A.

“…Pancreatic islet cell regeneration is considered to be important in the onset and progression of diabetes and as a potential cell therapy. Current hypotheses,…”
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