Search Results - "Walker, GJ"

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease by Walker, Gareth J, Harrison, James W, Heap, Graham A, Voskuil, Michiel D, Andersen, Vibeke, Anderson, Carl A, Ananthakrishnan, Ashwin N, Barrett, Jeffrey C, Beaugerie, Laurent, Bewshea, Claire M, Cole, Andy T, Cummings, Fraser R, Daly, Mark J, Ellul, Pierre, Fedorak, Richard N, Festen, Eleonora A. M, Florin, Timothy H, Gaya, Daniel R, Halfvarson, Jonas, Hart, Ailsa L, Heerasing, Neel M, Hendy, Peter, Irving, Peter M, Jones, Samuel E, Koskela, Jukka, Lindsay, James O, Mansfield, John C, McGovern, Dermot, Parkes, Miles, Pollok, Richard C. G, Ramakrishnan, Subramaniam, Rampton, David S, Rivas, Manuel A, Russell, Richard K, Schultz, Michael, Sebastian, Shaji, Seksik, Philippe, Singh, Abhey, So, Kenji, Sokol, Harry, Subramaniam, Kavitha, Todd, Anthony, Annese, Vito, Weersma, Rinse K, Xavier, Ramnik, Ward, Rebecca, Weedon, Michael N, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq

“…IMPORTANCE: Use of thiopurines may be limited by myelosuppression. TPMT pharmacogenetic testing identifies only 25% of at-risk patients of European ancestry…”
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A Comparison of Environmental Values and Attitudes Between Chinese in Canada and Anglo-Canadians by Deng, Jinyang, Walker, Gordon J., Swinnerton, Guy

“…This study examines similarities and differences in environmental values and attitudes between two cultural groups—Chinese in Canada and Anglo-Canadians. The…”
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No effect of fluid intake on neutrophil responses to prolonged cycling by BISHOP, N. C, SCANLON, G. A, WALSH, N. P, MCCALLUM, L. J, WALKER, G. J

“…Ingesting carbohydrate beverages during prolonged exercise is associated with fewer numbers of circulating neutrophils and attenuated neutrophil functional…”
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Activating point mutations in cyclin-dependent kinase 4 are not seen in sporadic pituitary adenomas, insulinomas or Leydig cell tumours by Vax, VV, Bibi, R, Diaz-Cano, S, Gueorguiev, M, Kola, B, Borboli, N, Bressac-de Paillerets, B, Walker, GJ, Dedov, Grossman, AB, Korbonits, M

“…Cell cycle dysregulation is one of the defining features of cancer. Cyclin-dependent kinase 4 (CDK4), together with its regulatory subunit cyclin D, governs…”
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Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer by Young, Joanne, Barker, Melissa A, Simms, Lisa A, Walsh, Michael D, Biden, Kelli G, Buchanan, Daniel, Buttenshaw, Ron, Whitehall, Vicki L J, Arnold, Sven, Jackson, Leigh, Kambara, Takeshi, Spring, Kevin J, Jenkins, Mark A, Walker, Graeme J, Hopper, John L, Leggett, Barbara A, Jass, Jeremy R

“…Recently, an alternative pathway of tumorigenesis has been identified in the colorectum associated with serrated precursor lesions, variable levels of…”
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Pathways to Melanoma Development: Lessons from the Mouse by Walker, Graeme J., Hayward, Nicholas K.

“…Because of subtle differences between mouse and human skin, mice have traditionally not been an ideal model to study melanoma development. Understanding of the…”
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Salivary IgA responses to prolonged intensive exercise following caffeine ingestion by BISHOP, Nicolette C, WALKER, Gary J, SCANLON, Gabriella A, RICHARDS, Stephen, ROGERS, Eleanor

“…Prolonged, intensive exercise is associated with a reduction in concentration and secretion of salivary IgA (s-IgA). Saliva composition and secretion are under…”
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Lymphocyte responses to influenza and tetanus toxoid in vitro following intensive exercise and carbohydrate ingestion on consecutive days by Bishop, Nicolette C, Walker, Gary J, Bowley, Lee A, Evans, Kate F, Molyneux, Karen, Wallace, Fiona A, Smith, Alice C

“…1 School of Sport and Exercise Sciences, Loughborough University, Loughborough, Leicestershire; 2 Department of Infection, Immunity and Inflammation,…”
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Ethnic/Racial and Gender Variations Among Meanings Given to, and Preferences for, the Natural Environment by Randy J. Virden, Gordon J. Walker

“…The purpose of this study was to explore how ethnicity/race and gender, in combination, influence person-natural environment interactions. The sample consisted…”
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Segmenting Casino Tourists by Mode of Experience by Walker, Gordon J., Hinch, Tom

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Loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression by REED, J. A, LOGANZO, F. JR, ALBINO, A. P, SHEA, C. R, WALKER, G. J, FLORES, J. F, GLENDENING, J. M, BOGDANY, J. K, SHEIL, M. J, HALUSKA, F. G, FOUNTAIN, J. W

“…Sporadic and familial malignant melanoma susceptibility has been linked to defects in the chromosomal region 9p21. Recently, a putative 9p21 tumor suppressor…”
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Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets by Walker, Graeme J., Flores, José F., Glendening, J. Michael, Lin, Amy (Hsui-Ti), Markl, Isabel D. C., Fountain, Jane W.

“…The cyclin‐dependent kinase inhibitor 2A (CDKN2A), or p16INK4a, gene on 9p21 is important in the genesis of both familial and sporadic melanoma. Homozygous…”
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Self-construal and pilgrimage travel by Lankford, Samuel V., Dieser, Rodney B., Walker, Gordon J.

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Low frequency of p16/CDKN2A methylation in sporadic melanoma: Comparative approaches for methylation analysis of primary tumors by GONZALGO, M. L, BENDER, C. M, YOU, E. H, GLENDENING, J. M, FLORES, J. F, WALKER, G. J, HAYWARD, N. K, JONES, P. A, FOUNTAIN, J. W

“…Methylation of the 5' CpG island of the p16 tumor suppressor gene represents one possible mechanism for inactivation of this cell cycle regulatory gene that is…”
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The effect of caffeine ingestion on neutrophil oxidative burst responses following prolonged cycling by Walker, Gary J, Caudwell, Phillipa, Dixon, Natalie, Bishop, Nicolette C

“…This study investigated the effect of caffeine ingestion on neutrophil oxidative burst responses to prolonged cycling. In a two part study, 19 endurance…”
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Deletion mapping suggests that the 1p22 melanoma susceptibility gene is a tumor suppressor localized to a 9-mb interval by Walker, Graeme J., Indsto, James O., Sood, Raman, Faruque, Mezbah U., Hu, Ping, Pollock, Pam M., Duray, Paul, Holland, Elizabeth A., Brown, Kevin, Kefford, Richard F., Trent, Jeffrey M., Mann, Graham J., Hayward, Nicholas K.

“…Loss of the short arm of chromosome 1 is frequently observed in many tumor types, including melanoma. We recently localized a third melanoma susceptibility…”
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PTEN inactivation is rare in melanoma tumours but occurs frequently in melanoma cell lines by Pollock, P M, Walker, G J, Glendening, J M, Que Noy, T, Bloch, N C, Fountain, J W, Hayward, N K

“…Deletions detected in cytogenetic and loss of heterozygosity (LOH) studies indicate that at least one tumour suppressor gene maps to the long arm of chromosome…”
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p16INK4A and p14ARF tumour suppressors in melanoma: lessons from the mouse by Walker, Graeme J, Hayward, Nicholas K

“…Intriguingly, in the study of [Paul Krimpenfort] and colleagues,11 when mice, which produced a truncated unstable Ink4a protein, were crossed with [Arf]…”
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Inter- and Intra-Gender Similarities and Differences in Motivations for Casino Gambling by Walker, Gordon J., Hinch, Thomas D., Weighill, A. J.

“…The two objectives of this study were to examine if motivations for casino gambling vary by gender and, based on motivations for casino gambling, to ascertain…”
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Ethnicity, Acculturation, Self-Construal, and Motivations for Outdoor Recreation by Walker, Gordon J., Deng, Jinyang, Dieser, Rodney B.

“…Research on the leisure of racial and ethnic groups has recently been criticized for a variety of different reasons. In response to some of these concerns,…”
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