Search Results - "Walker, Ernest M."

Environmental mercury and its toxic effects by Rice, Kevin M, Walker, Jr, Ernest M, Wu, Miaozong, Gillette, Chris, Blough, Eric R

“…Mercury exists naturally and as a man-made contaminant. The release of processed mercury can lead to a progressive increase in the amount of atmospheric…”
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Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2 by Wu, Miaozong, Desai, Devashish H., Kakarla, Sunil K., Katta, Anjaiah, Paturi, Satyanarayana, Gutta, Anil K., Rice, Kevin M., Walker Jr, Ernest M., Blough, Eric R.

“…Background Aging‐related hyperglycemia is associated with increased oxidative stress and diminished muscle glucose transporter‐4 (Glut4) that may be regulated,…”
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Modified SAMs and templates for achieving self-alignment of full wafers by Emanuel, Ako, Walker, Ernest M., Hallen, Hans D.

“…Self-assembly of structures that are more than a few millimeters in size is a current problem that can have broad applications in new ways to construct the…”
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Chronic acetaminophen attenuates age-associated increases in cardiac ROS and apoptosis in the Fischer Brown Norway rat by Kakarla, Sunil K., Fannin, Jacqueline C., Keshavarzian, Saba, Katta, Anjaiah, Paturi, Satyanarayana, Nalabotu, Siva K., Wu, Miaozong, Rice, Kevin M., Manzoor, Kamran, Walker, Ernest M., Blough, Eric R.

“…There is a growing need for pharmacological agents to manage cardiovascular disease in the rapidly growing elderly population. Here, we determine if…”
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Age-associated changes in hearts of male Fischer 344/Brown Norway F1 rats by Walker, Jr, Ernest M, Nillas, Michael S, Mangiarua, Elsa I, Cansino, Sylvestre, Morrison, Ryan G, Perdue, Romaine R, Triest, William E, Wright, Gary L, Studeny, Mark, Wehner, Paulette, Rice, Kevin M, Blough, Eric R

“…Aging is associated with left ventricular hypertrophy, dilatation, and fibrosis of the heart. The Fischer 344/Brown Norway F1 (F344/BNF1) rat is recommended…”
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Acetaminophen combinations protect against iron-induced cardiac damage in gerbils by Walker, Jr, Ernest M, Morrison, Ryan G, Dornon, Lucy, Laurino, Joseph P, Walker, Sandra M, Studeny, Mark, Wehner, Paulette S, Rice, Kevin M, Wu, Miaozong, Blough, Eric R

“…This study tested if acetaminophen, N-methyl-D-glucamine dithiocarbamate (NMGDTC), deferoxamine, and combinations of these agents reduce excess iron content,…”
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Environmental Mercury and Its Toxic Effects by Rice, Kevin M, Walker, Ernest M. Jr, Wu, Miaozong, Gillette, Chris, Blough, Eric R

“…Mercury exists naturally and as a man-made contaminant. The release of processed mercury can lead to a progressive increase in the amount of atmospheric…”
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Acetaminophen protects against iron-induced cardiac damage in gerbils by Walker, Jr, Ernest M, Epling, Christopher P, Parris, Cordel, Cansino, Silvestre, Ghosh, Protip, Desai, Devashish H, Morrison, Ryan G, Wright, Gary L, Wehner, Paulette, Mangiarua, Elsa I, Walker, Sandra M, Blough, Eric R

“…There are few effective agents that safely remove excess iron from iron-overloaded individuals. Our goal was to evaluate the iron-removing effectiveness of…”
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Deferasirox removes cardiac iron and attenuates oxidative stress in the iron‐overloaded gerbil by Al‐Rousan, Rabaa M., Paturi, Satyanarayana, Laurino, Joseph P., Kakarla, Sunil K., Gutta, Anil K., Walker, Ernest M., Blough, Eric R.

“…Iron‐induced cardiovascular disease is the leading cause of death in iron‐overloaded patients. Deferasirox is a novel, once daily oral iron chelator that was…”
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Long-term efficacy of deferasirox in preventing cardiovascular complications in the iron-overloaded gerbil by Al-Rousan, Rabaa M, Manzoor, Kamran, Paturi, Satyanarayana, Arvapalli, Ravi Kumar, Laurino, Joseph P, Darnon, Lucy, Walker, Ernest M, Blough, Eric R

“…Iron-induced cardiovascular disease is the leading cause of death in iron-overloaded patients. Deferasirox is a novel tridentate oral chelator that exhibits a…”
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Increased sensitivity of the obese Zucker rat to deoxycorticosterone-salt-induced hypertension by Morrison, Ryan G, Carpenter, A Betts, Moore, Stephany K, Mangiarua, Elsa I, Valentovic, Monica A, Walker, Ernest M, Wehner, Paulette S, Rhoten, William B, Touchon, Robert C, McCumbee, William D

“…OBJECTIVE The objective of this study was to test the hypothesis that obesity increases the sensitivity of rats to experimentally induced hypertension. DESIGN…”
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Deferasirox protects against iron-induced hepatic injury in Mongolian gerbil by Al-Rousan, Rabaa M, Rice, Kevin M, Katta, Anjaiah, Laurino, Joseph, Walker, Ernest M, Wu, Miaozong, Triest, William E, Blough, Eric R

“…Iron overload is associated with an increased risk of liver complications including fibrosis, cirrhosis, and hepatocellular carcinoma. Deferasirox is a new…”
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Deferasirox Decreases Age-Associated Iron Accumulation in the Aging F344XBN Rat Heart and Liver by Arvapalli, Ravi Kumar, Paturi, Satyanarayana, Laurino, Joseph P, Katta, Anjaiah, Kakarla, Sunil K, Gadde, Murali K, Wu, Miaozong, Rice, Kevin M, Walker, Ernest M, Wehner, Paulette, Blough, Eric R

“…It is thought that aging in rats and humans is associated with increases in iron accumulation and cell apoptosis. Here, we examine the relationship between…”
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Adaptation of Haplobothrium globuliforme (Cestoda: Pseudophyllidea) to the Intestinal Architecture of the Bowfin (Amia calva L) by Joy, James E, Triest, William E, Walker, Ernest M

“…Haplobothrium globuliforme maintains its position in the proximal mid-gut epithelium of Amia calva with the aid of tentacles, i.e., proboscides, everted from…”
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Aging influences multiple indices of oxidative stress in the heart of the Fischer 344/NNia x Brown Norway/BiNia rat by Asano, Shinichi, Rice, Kevin M, Kakarla, Sunil, Katta, Anjaiah, Desai, Devashish H, Walker, Ernest M, Wehner, Paulette, Blough, Eric R

“…We report the influence of aging on multiple markers of oxidative-nitrosative stress in the heart of adult (6-month), aged (30-month) and very aged (36-month)…”
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Fluprostenol-induced MAPK signaling is independent of aging in Fischer 344/NNiaHSd x Brown Norway/BiNia rat aorta by Rice, Kevin M, Walker, Ernest M, Kakarla, Sunil K, Paturi, Satyanarayana, Wu, Miaozong, Narula, Sumit, Blough, Eric R

“…The factors that regulate vascular mechanotransduction and how this process may be altered with aging are poorly understood and have not been widely studied…”
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Mobilization of Iron by Chiral and Achiral Anionic 3-Hydroxypyrid-4-ones by Molenda, John Josef, Jones, Mark M, Johnston, David S, Walker, Ernest M, Cannon, Donald J

“…In the search for 3-hydroxypyrid-4-ones with enhanced iron-mobilizing ability, seven chiral, anionic amino acid derivatives of maltol…”
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Vitamin A status affects the development of diabetes and insulitis in BB rats by Driscoll, Henry K., Chertow, Bruce S., Jelic, Tomislav M., Baltaro, Richard J., Chandor, Stebbins B., Walker, Ernest M., Dadgari, Joseph M., Pofahl, A.Beverley

“…BB/Wor rats develop autoimmune diabetes mellitus with many features in common with human insulin-dependent diabetes mellitus. Since retinoids are known to have…”
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Mobilization of lead in mice by administration of monoalkyl esters of meso-2,3-dimercaptosuccinic acid by Walker, Jr, E M, Stone, A, Milligan, L B, Gale, G R, Atkins, L M, Smith, A B, Jones, M M, Singh, P K, Basinger, M A

“…The following six monoalkyl esters of meso-2,3-dimercaptosuccinic acid (DMSA) were synthesized and evaluated for relative activities in mobilizing lead from…”
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Anti-arrhythmic Effect of Chronic Acetaminophen Treatment in the Aging Fischer Brown Norway Rat Involves Connexin-43: 928 May 30 2:45 PM - 3:00 PM by Desai, Devashish H., Meduru, Sarath, Neal, Megan L., Rice, Kevin M., Walker, Ernest M., Wehner, Paulette S., Blough, Eric R.

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