Search Results - "Walker, Don"

Investigating interactions between phospholipase B-Like 2 and antibodies during Protein A chromatography by Tran, Benjamin, Grosskopf, Vanessa, Wang, Xiangdan, Yang, Jihong, Walker, Don, Yu, Christopher, McDonald, Paul

“…•PLBL2 levels in the Protein A pool do not always correlate with total host-cell protein levels.•PLBL2 co-elution during Protein A is highly dependent on…”
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Antenatal Sildenafil Treatment Attenuates Pulmonary Hypertension in Experimental Congenital Diaphragmatic Hernia by LUONG, Christina, REY-PERRA, Juliana, NADEEM, Khurram, MORGAN, Beverly, EATON, Farah, DYCK, Jason R, ARCHER, Stephen L, THEBAUD, Bernard, VADIVEL, Arul, GILMOUR, Greg, SAUVE, Yves, KOONEN, Debby, WALKER, Don, TODD, Kathryn G, GRESSENS, Pierre, KASSIRI, Zamaneh

“…Lung hypoplasia and persistent pulmonary hypertension of the newborn limit survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting…”
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Single-ion adsorption and switching in carbon nanotubes by Bushmaker, Adam W., Oklejas, Vanessa, Walker, Don, Hopkins, Alan R., Chen, Jihan, Cronin, Stephen B.

“…Single-ion detection has, for many years, been the domain of large devices such as the Geiger counter, and studies on interactions of ionized gasses with…”
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Improving asthma self-management education through inhaler labeling by Dikranian, Lea C., Irish, D. Elizabeth, Shanley, Kathleen E., Walker, Don R., de Waal Malefyt, Stephen K.

“…Improper use and poor understanding of asthma medications can lead to poorly controlled asthma, emergency department visits, and hospitalizations for children…”
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Reconstructing the history of helminth prevalence in the UK by Ryan, Hannah, Flammer, Patrik G, Nicholson, Rebecca, Loe, Louise, Reeves, Ben, Allison, Enid, Guy, Christopher, Doriga, Inés Lopez, Waldron, Tony, Walker, Don, Kirchhelle, Claas, Larson, Greger, Smith, Adrian L

“…Intestinal helminth parasites (worms) have afflicted humans throughout history and their eggs are readily detected in archaeological deposits including at…”
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In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate by Abuasal, Bilal S, Bolger, Michael B, Walker, Don K, Kaddoumi, Amal

“…The aim of this work was to extrapolate in vitro and preclinical animal data to simulate the pharmacokinetic parameters of UK-343,664, a P-glycoprotein (P-gp)…”
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Use of esophageal balloon manometry in the management of pediatric acute respiratory distress syndrome by Insley, Elena, Pezzano, Chad, Ambati, Shashikanth, Lydon, Darren, Walker, Don, Barry, Suzanne

“…There is paucity of literature regarding the use of esophageal balloon manometry in the management of Pediatric Acute Respiratory Distress Syndrome. We…”
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Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate by Clark, Robert L., Edwards, Tammye L., Longo, Monica, Kinney, Joseph, Walker, Don K., Rhodes, Jon, Clode, Sally A., Rückle, Thomas, Wells, Timothy, Andenmatten, Nicole, Huber, Anna Christine

“…Background Combination medicines including an artemisinin are the mainstay of antimalarial therapy. Artemisinins are potent embryotoxicants in animal species…”
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Narrowband Polaritonic Thermal Emitters Driven by Waste Heat by Lu, Guanyu, Nolen, Joshua Ryan, Folland, Thomas G, Tadjer, Marko J, Walker, Don Greg, Caldwell, Joshua D

“…There are a broad range of applications for narrowband long-wave infrared (LWIR) sources, especially within the 8–12 μm atmospheric window. These include…”
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Property-Based Design:  Optimization of Drug Absorption and Pharmacokinetics by van de Waterbeemd, Han, Smith, Dennis A, Beaumont, Kevin, Walker, Don K

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Subcell Light Current-Voltage Characterization of Irradiated Multijunction Solar Cell by Walker, Don, Nocerino, John, Yue, Yao, Mann, Colin J., Liu, Simon H.

“…The degradation of individual subcell J-V parameters, such as short circuit current, open circuit voltage, fill factor, and power of a GaInP/GaInAs/Ge triple…”
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Design of Substrate-Based Inhibitors of Human β-Secretase by Tung, Jay S, Davis, David L, Anderson, John P, Walker, Don E, Mamo, Shumeye, Jewett, Nancy, Hom, Roy K, Sinha, Sukanto, Thorsett, Eugene D, John, Varghese

“…By use of the effectively cleaved β-secretase (BACE) substrate (1), incorporation of a statine in P1 resulted in a weak inhibitor 13 of the enzyme. Further…”
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SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data by Mantell, Simon J., Stephenson, Peter T., Monaghan, Sandra M., Maw, Graham N., Trevethick, Michael A., Yeadon, Michael, Walker, Don K., Selby, Matthew D., Batchelor, David V., Rozze, Stuart, Chavaroche, Helene, Lemaitre, Arnaud, Wright, Karen N., Whitlock, Lynsey, Stuart, Emilio F., Wright, Patricia A., Macintyre, Fiona

“…The pharmacological and pharmacokinetic SAR of a series of inhaled A2A agonists is described, leading through to a comparison of preclinical and clinical…”
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SPECIES DIFFERENCES IN THE DISPOSITION OF THE CCR5 ANTAGONIST, UK-427,857, A NEW POTENTIAL TREATMENT FOR HIV by WALKER, Don K, ABEL, Samantha, COMBY, Pierre, MUIRHEAD, Gary J, NEDDERMAN, Angus N. R, SMITH, Dennis A

“…UK-427,857 (4, 4-difluoro- N -{(1 S )-3-[ exo -3-(3-isopropyl-5-methyl-4 H…”
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SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data by Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Walker, Don K, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Lemaitre, Arnaud, Wright, Karen N, Whitlock, Lynsey, Stuart, Emilio F, Wright, Patricia A, Macintyre, Fiona

“…COPD is a major cause of mortality in the western world. A(2A) agonists are postulated to reduce the lung inflammation that causes COPD. The cardiovascular…”
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Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-Secretase by Hom, Roy K, Fang, Larry Y, Mamo, Shumeye, Tung, Jay S, Guinn, Ashley C, Walker, Don E, Davis, David L, Gailunas, Andrea F, Thorsett, Eugene D, Sinha, Sukanto, Knops, Jeroen E, Jewett, Nancy E, Anderson, John P, John, Varghese

“…We describe the development of statine-based peptidomimetic inhibitors of human β-secretase (BACE). The conversion of the peptide inhibitor 1 into…”
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With images in mind, 2022: photographywritingmusic by Wagner, Jon, Walker, Don

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With images in mind, 2022 by Wagner, Jon, Walker, Don

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Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease by MANTELL, Simon J, STEPHENSON, Peter T, BATCHELOR, David V, ROZZE, Stuart, CHAVAROCHE, Helene, HOBSON, Tim J, DODD, Peter G, LEMAITRE, Arnaud, WRIGHT, Karen N, STUART, Emilio F, MONAGHAN, Sandra M, MAW, Graham N, TREVETHICK, Michael A, YEADON, Michael, KEIR, Ruth F, WALKER, Don K, JONES, Rhys M, SELBY, Matthew D

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Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease by Mantell, Simon J, Stephenson, Peter T, Monaghan, Sandra M, Maw, Graham N, Trevethick, Michael A, Yeadon, Michael, Keir, Ruth F, Walker, Don K, Jones, Rhys M, Selby, Matthew D, Batchelor, David V, Rozze, Stuart, Chavaroche, Helene, Hobson, Tim J, Dodd, Peter G, Lemaitre, Arnaud, Wright, Karen N, Stuart, Emilio F

“…COPD is a major cause of mortality in the western world. A(2A) agonists are postulated to reduce the lung inflammation that causes COPD. The cardiovascular…”
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