Search Results - "Walker, D. C."
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Maternal high-fat intake alters presynaptic regulation of dopamine in the nucleus accumbens and increases motivation for fat rewards in the offspring
Published in Neuroscience (10-03-2011)“…Abstract High caloric intake during early postnatal development can have long term consequences for the offspring. We previously reported that the adult…”
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Developmental Responses of the Lateral Hypothalamus to Leptin in Neonatal Rats, and its Implications for the Development of Functional Connections with the Ventral Tegmental Area
Published in Journal of neuroendocrinology (01-03-2016)“…Food intake is regulated by a close communication between the hypothalamus and the mesocorticolimbic pathways, which are still developing during the perinatal…”
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Sensitivity to stress among the offspring of parents with bipolar disorder: a study of daytime cortisol levels
Published in Psychological medicine (01-11-2011)“…It is well known that the hypothalamic-pituitary-adrenal (HPA) axis is compromised in major depression and bipolar disorder. There is increasing evidence that…”
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Participation of endocannabinoids in rapid suppression of stress responses by glucocorticoids in neonates
Published in Neuroscience (26-09-2013)“…Highlights ► Neonates exhibit rapid GC feedback after stress, mediated partly by eCBs at the CB1R. ► AM251 treatment impairs the normal return of…”
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Questioning the Role of Carotid Artery Ultrasound in Assessing Fluid Responsiveness in Critical Illness: A Systematic Review and Meta-Analysis
Published in Critical care research and practice (27-04-2024)“…Background. A noninvasive and accurate method of identifying fluid responsiveness in hemodynamically unstable patients has long been sought by physicians…”
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Multiscale Model Development for Electrical Properties of Thyroid and Parathyroid Tissues
Published in IEEE open journal of engineering in medicine and biology (01-01-2024)“…Goal: Electrical impedance spectroscopy (EIS) has been suggested as a possible technique to differentiate between thyroid and parathyroid tissue during…”
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Glucocorticoid rhythms control the rhythm of expression of the clock protein, Period2, in oval nucleus of the bed nucleus of the stria terminalis and central nucleus of the amygdala in rats
Published in Neuroscience (01-01-2006)“…We investigated the involvement of the adrenal glucocorticoid, corticosterone, in the control of the rhythmic expression of the circadian clock protein,…”
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Neonatal Onset of Leptin Signalling in Dopamine Neurones of The Ventral Tegmental Area in The Rat
Published in Journal of neuroendocrinology (01-12-2014)“…Leptin inhibits feeding by acting on hypothalamic and mesolimbic dopamine (DA) pathways involved in the homeostatic and hedonic control of energy balance. In…”
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Multiparity Reveals the Blunting Effect of Breastfeeding on Physiological Reactivity to Psychological Stress
Published in Journal of neuroendocrinology (01-07-2006)“…Rat studies show that hypothalamic‐pituitary‐adrenal (HPA) responsiveness to physical and emotional stressors is attenuated during lactation, although…”
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Pups Presence Eliminates the Stress Hyporesponsiveness of Early Lactating Females to a Psychological Stress Representing a Threat to the Pups
Published in Journal of neuroendocrinology (01-05-2003)“…Blunted neuroendocrine responses to stress are reported in lactating females after exposure to various stressors. However, many of the stimuli used in these…”
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Reduced anticipatory dopamine responses to food in rats exposed to high fat during early development
Published in International Journal of Obesity (01-06-2013)“…We have previously demonstrated that exposure to high fat (HF) during early development alters the presynaptic regulation of mesolimbic dopamine (DA), and…”
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The epitheliome: agent-based modelling of the social behaviour of cells
Published in BioSystems (01-08-2004)“…We have developed a new computational modelling paradigm for predicting the emergent behaviour resulting from the interaction of cells in epithelial tissue. As…”
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Improved Retention Associated With Community-Based Accompaniment for Antiretroviral Therapy Delivery in Rural Rwanda
Published in Clinical infectious diseases (01-05-2013)“…Background. Minimizing death and ensuring high retention and good adherence remain ongoing challenges for human immunodeficiency virus (HIV) treatment…”
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High levels of cortisol among adolescent offspring of parents with bipolar disorder: a pilot study
Published in Psychoneuroendocrinology (2004)“…The hypothalamic-pituitary-adrenal (HPA) axis is compromised at several levels in major depressive and bipolar disorder (BD). However, it is not known whether…”
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Trimethoprim-sulfamethoxazole-associated acute febrile neutrophilic dermatosis: Case report and review of drug-induced Sweet's syndrome
Published in Journal of the American Academy of Dermatology (01-05-1996)“…Sweet's syndrome, or acute febrile neutrophilic dermatosis, is characterized by fever, neutrophilia, and painful erythematous cutaneous plaques that contain a…”
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Safety evaluation of polydextrose in infant formula using a suckling piglet model
Published in Food and chemical toxicology (01-07-2009)“…Oligosaccharides, the third largest component in human milk, are virtually absent from cow’s milk and most infant formula. Prebiotic carbohydrates like…”
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Increasing the statistical power of animal experiments with historical control data
Published in Nature neuroscience (01-04-2021)“…Low statistical power reduces the reliability of animal research; yet, increasing sample sizes to increase statistical power is problematic for both ethical…”
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Corticotropin-Releasing Factor, But Not Corticosterone, Is Involved in Stress-Induced Relapse to Heroin-Seeking in Rats
Published in The Journal of neuroscience (01-04-1997)“…We showed previously that brief footshock stress and priming injections of heroin reinstate heroin-seeking after prolonged drug-free periods. Here, we examined…”
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From pathway to population--a multiscale model of juxtacrine EGFR-MAPK signalling
Published in BMC systems biology (26-11-2008)“…Most mathematical models of biochemical pathways consider either signalling events that take place within a single cell in isolation, or an 'average' cell…”
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Etiology of infantile autism : a review of recent advances in genetic and neurobiological research
Published in Journal of psychiatry & neuroscience (01-03-1999)“…The etiology of autism is complex, and in most cases the underlying pathologic mechanisms are unknown. Autism is a hetereogeneous disorder, diagnosed…”
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