Search Results - "Walker, Alyssa"

Colonization of the Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate by Walker, Alyssa C, Bhargava, Rohan, Vaziriyan-Sani, Alfonso S, Pourciau, Christine, Donahue, Emily T, Dove, Autumn S, Gebhardt, Michael J, Ellward, Garrett L, Romeo, Tony, Czyż, Daniel M

“…Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric…”
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ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis by Chung, Seung J., Nagaraju, Ganji Purnachandra, Nagalingam, Arumugam, Muniraj, Nethaji, Kuppusamy, Panjamurthy, Walker, Alyssa, Woo, Juhyung, Győrffy, Balázs, Gabrielson, Ed, Saxena, Neeraj K., Sharma, Dipali

“…ADIPOQ/adiponectin, an adipocytokine secreted by adipocytes in the breast tumor microenvironment, negatively regulates cancer cell growth hence increased…”
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Multitier regulation of the E. coli extreme acid stress response by CsrA by Gorelik, Mark G, Yakhnin, Helen, Pannuri, Archana, Walker, Alyssa C, Pourciau, Christine, Czyz, Daniel, Romeo, Tony, Babitzke, Paul

“…CsrA is an RNA-binding protein that regulates processes critical for growth and survival, including central carbon metabolism, motility, biofilm formation,…”
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Bacteria-Derived Protein Aggregates Contribute to the Disruption of Host Proteostasis by Walker, Alyssa C, Bhargava, Rohan, Dove, Autumn S, Brust, Amanda S, Owji, Ali A, Czyż, Daniel M

“…Neurodegenerative protein conformational diseases are characterized by the misfolding and aggregation of metastable proteins encoded within the host genome…”
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Quantification of Bacterial Loads in Caenorhabditis elegans by Walker, Alyssa C, Bhargava, Rohan, Vaziriyan-Sani, Alfonso S, Brust, Amanda S, Czyz, Daniel M

“…is a ubiquitous free-living nematode that feeds on bacteria. The organism was introduced into a laboratory setting in the 1970s and has since gained popularity…”
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Time-off-pick Assay to Measure Caenorhabditis elegans Motility by Walker, Alyssa C, Bhargava, Rohan, Brust, Amanda S, Owji, Ali A, Czyż, Daniel M

“…is a simple metazoan that is often used as a model organism to study various human ailments with impaired motility phenotypes, including protein conformational…”
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Breaking Boundaries in Pneumonia Diagnostics: Transitioning from Tradition to Molecular Frontiers with Multiplex PCR by Walker, Alyssa M, Timbrook, Tristan T, Hommel, Benjamin, Prinzi, Andrea M

“…The advent of rapid molecular microbiology testing has revolutionized infectious disease diagnostics and is now impacting pneumonia diagnosis and management…”
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PGE2 Augments Inflammasome Activation and M1 Polarization in Macrophages Infected With Salmonella Typhimurium and Yersinia enterocolitica by Sheppe, Austin E F, Kummari, Evangel, Walker, Alyssa, Richards, Angela, Hui, Winnie W, Lee, Jung Hwa, Mangum, Lauren, Borazjani, Abdolsamad, Ross, Matthew K, Edelmann, Mariola J

“…Eicosanoids are cellular metabolites, which shape the immune response, including inflammatory processes in macrophages. The effects of these lipid mediators on…”
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Neuropsychological Performance in Alzheimer’s Disease versus Late-Life Depression: A Systematic Review and Meta-Analysis by Barlet, Brianna D, Hauson, Alexander O, Pollard, Anna A, Zhang, Emily Z, Nemanim, Natasha M, Sarkissians, Sharis, Lackey, Nick S, Stelmach, Nicholas P, Walker, Alyssa D, Carson, Bryce T, Flora-Tostado, Christopher, Reszegi, Katalin, Allen, Kenneth E, Viglione, Donald J

“…Abstract Objective Despite decades of research, neuropsychological tests (NPTs) that clearly differentiate between Alzheimer’s disease (AD) and late-life…”
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Neuropsychological Assessment and Screening in Heart Failure: a Meta-Analysis and Systematic Review by Connors, Eric J., Hauson, Alexander O., Barlet, Brianna D., Sarkissians, Sharis, Stelmach, Nicholas P., Walker, Alyssa D., Nemanim, Natasha M., Greenwood, Kristina L., Chesher, Nicholas J., Wollman, Scott C., Allen, Kenneth E., Hall, Matthew G., Flora-Tostado, Christopher

“…A variety of neuropsychological changes secondary to heart failure have been documented in the literature. However, what remains unclear are which…”
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Identification of proteotoxic and proteoprotective bacteria that non-specifically affect proteins associated with neurodegenerative diseases by Walker, Alyssa C., Bhargava, Rohan, Bucher, Michael J., Argote, Yoan M., Brust, Amanda S., Czyż, Daniel M.

“…There are no cures for neurodegenerative protein conformational diseases (PCDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s…”
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Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway by Fogg, Kaitlin C, Miller, Andrew E, Li, Ying, Flanigan, Will, Walker, Alyssa, O'Shea, Andrea, Kendziorski, Christina, Kreeger, Pamela K

“…Alternatively-activated macrophages (AAMs), an anti-inflammatory macrophage subpopulation, have been implicated in the progression of high grade serous ovarian…”
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Automating Aggregate Quantification in Caenorhabditis elegans by Vaziriyan-Sani, Alfonso S, Handy, Robert D, Walker, Alyssa C, Pagolu, Carol Navya, Enslow, Samantha M, Czyż, Daniel M

“…A rise in the prevalence of neurodegenerative protein conformational diseases (PCDs) has fostered a great interest in this subject over the years. This…”
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Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness by Leineweber, William D., Rowell, Maya Z., Ranamukhaarachchi, Sural K., Walker, Alyssa, Li, Yajuan, Villazon, Jorge, Mestre-Farrera, Aida, Hu, Zhimin, Yang, Jing, Shi, Lingyan, Fraley, Stephanie I.

“…Contact with dense collagen I (Col1) can induce collective invasion of triple negative breast cancer (TNBC) cells and transcriptional signatures linked to poor…”
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Biological fuel cell and an application as a reserve power source by Walker, Alyssa L., Walker, Charles W.

“…A biological fuel cell was constructed in which the metabolism of glucose by yeast provided the electrons. A two compartment plexiglass fuel cell was…”
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Fospropofol: A New Sedative-Hypnotic Agent for Monitored Anesthesia Care by Moore, Gina D, Walker, Alyssa M, MacLaren, Robert

“…Objective: To summarize the published clinical data on fospropofol, critically review the safety and efficacy information, and provide pertinent information…”
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The extracellular matrix of ovarian cortical inclusion cysts modulates invasion of fallopian tube epithelial cells by Fleszar, Andrew J., Walker, Alyssa, Porubsky, Veronica, Flanigan, Will, James, Darian, Campagnola, Paul J., Weisman, Paul S., Kreeger, Pamela K.

“…A growing body of research supports the idea that the fallopian tube epithelium (FTE) is the precursor for most high-grade serous ovarian cancers (HGSOCs) but…”
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Oh my gut! Is the microbial origin of neurodegenerative diseases real? by Walker, Alyssa, Czyz, Daniel M

“…There is no cure or effective treatment for neurodegenerative protein conformational diseases (PCDs), such as Alzheimer's or Parkinson's diseases, mainly…”
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Multimodal impairment-based physical therapy for the treatment of patients with post-concussion syndrome: A retrospective analysis on safety and feasibility by Grabowski, Patrick, Wilson, John, Walker, Alyssa, Enz, Dan, Wang, Sijian

“…Abstract Objective Demonstrate implementation, safety and feasibility of multimodal, impairment-based physical therapy (PT) combining vestibular/oculomotor and…”
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Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation by Walker, Alyssa, Singh, Anju, Tully, Ellen, Woo, Juhyung, Le, Anne, Nguyen, Tu, Biswal, Shyam, Sharma, Dipali, Gabrielson, Edward

“…Autophagy can serve as a mechanism for survival of cells during nutrient deprivation by recycling cellular macromolecules and organelles transiently to provide…”
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