Search Results - "Walentynowicz, Kacper A"
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Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma
Published in Cell reports (Cambridge) (28-03-2023)“…Glioblastoma (GBM) is the most aggressive brain tumor, with a median survival of ∼15 months. Targeted approaches have not been successful in this tumor type…”
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In Search for Reliable Markers of Glioma-Induced Polarization of Microglia
Published in Frontiers in immunology (15-06-2018)“…Immune cells accumulating in the microenvironment of malignant tumors are tumor educated and contribute to its growth, progression, and evasion of antitumor…”
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Immune microenvironment of gliomas
Published in Laboratory investigation (01-05-2017)“…High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with…”
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Abstract IA10: Uncovering the ecology of glioblastoma with spatial digital profiling and single cell genotyping
Published in Cancer research (Chicago, Ill.) (01-11-2020)“…Glioblastoma (GBM) remains one of the biggest challenges in oncology, with median survival of ~15 months. Extreme heterogeneity of the GBM cells within each…”
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Abstract IA013: Genetic heterogeneity and tumor microenvironment in glioblastoma
Published in Cancer research (Chicago, Ill.) (15-05-2022)“…Glioblastoma (GBM), the most aggressive brain tumor, remains an unmet medical need. Despite aggressive chemotherapy, radiation and surgery, only 5.6% of…”
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Journal Article