Search Results - "Waldum, Helge L."

Types of Gastric Carcinomas by Waldum, Helge L, Fossmark, Reidar

“…Gastric cancer has reduced prevalence, but poor prognoses. To improve treatment, better knowledge of carcinogenesis and cells of origin should be sought…”
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Adverse Effects of Proton Pump Inhibitors-Evidence and Plausibility by Fossmark, Reidar, Martinsen, Tom C, Waldum, Helge L

“…Proton pump inhibitors (PPIs) have been increasingly used over the last decades and there are concerns about overuse and the numerous reported side-effects. It…”
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The Phylogeny and Biological Function of Gastric Juice-Microbiological Consequences of Removing Gastric Acid by Martinsen, Tom C, Fossmark, Reidar, Waldum, Helge L

“…Gastric juice is a unique combination of hydrochloric acid (HCl), lipase, and pepsin. Acidic gastric juice is found in all vertebrates, and its main function…”
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Gastric cancer and gastrin: on the interaction of Helicobacter pylori gastritis and acid inhibitory induced hypergastrinemia by Waldum, Helge L., Rehfeld, Jens F.

“…Gastric cancer, a disease with a reduced frequency for decades, now appears to be on the rise again in young Americans. The epidemiology of gastric cancer…”
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The Enterochromaffin-like [ECL] Cell-Central in Gastric Physiology and Pathology by Waldum, Helge L, Sørdal, Øystein F, Mjønes, Patricia G

“…Studies on the regulation of gastric and pancreatic secretion began more than 100 years ago. Secretin was the first hormone postulated to exist, initiating the…”
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Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis by Granlund, Atle van Beelen, Flatberg, Arnar, Østvik, Ann E, Drozdov, Ignat, Gustafsson, Bjørn I, Kidd, Mark, Beisvag, Vidar, Torp, Sverre H, Waldum, Helge L, Martinsen, Tom Christian, Damås, Jan Kristian, Espevik, Terje, Sandvik, Arne K

“…In inflammatory bowel disease (IBD), genetic susceptibility together with environmental factors disturbs gut homeostasis producing chronic inflammation. The…”
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Gastrin May Mediate the Carcinogenic Effect of Helicobacter pylori Infection of the Stomach by Waldum, Helge L., Hauso, Øyvind, Sørdal, Øystein F., Fossmark, Reidar

“…Gastric cancer occurs almost exclusively in patients with gastritis. Since Helicobacter pylori (Hp) was proved to cause gastritis, Hp was also expected to play…”
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Helicobacter pylori and gastric acid: an intimate and reciprocal relationship by Waldum, Helge L., Kleveland, Per M., Sørdal, Øystein F.

“…Helicobacter pylori (Hp) is the main cause of gastritis, peptic ulcer disease and gastric cancer. There are still unanswered questions related to the…”
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The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival by Vange, Pål, Bruland, Torunn, Doseth, Berit, Fossmark, Reidar, Sousa, Mirta M L, Beisvag, Vidar, Sørdal, Øystein, Qvigstad, Gunnar, Waldum, Helge L, Sandvik, Arne K, Bakke, Ingunn

“…The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic…”
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Gastric Malignancies in United States in the Period From 2000 to 2018 by Waldum, Helge L.

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Gastric Juice: A Barrier Against Infectious Diseases by Martinsen, Tom C., Bergh, Kåre, Waldum, Helge L.

“…: All vertebrates produce gastric acid. Its main function is inactivation of ingested microorganisms. The majority of microbiological pathogens ingested never…”
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The increase in early-onset gastric carcinomas from 1995 is probably due to the introduction of proton pump inhibitors by Waldum, Helge L.

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Proton Pump Inhibitors and Mortality by Waldum, Helge L., Fossmark, Reidar

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Gastric cancer： Animal studies on the risk of hypoacidity and hypergastrinemia by Fossmark, Reidar, Qvigstad, Gunnar, Waldum, Helge-L

“…Gastric hypoacidity and hypergastrinaemia are seen in several conditions associated with an increased risk of gastric malignancy. Hypoacidity and…”
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Physiological and clinical significance of enterochromaffin-like cell activation in the regulation of gastric acid secretion by Cui, Guanglin, Waldum, Helge L

“…Gastric acid plays an important role in digesting food （especially protein）, iron absorption, and destroying swallowed micro-organisms. H＋ is secreted by the…”
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Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift by Waldum, Helge L., Öberg, Kjell, Sørdal, Øystein F., Sandvik, Arne K., Gustafsson, Bjørn I., Mjønes, Patricia, Fossmark, Reidar

“…Stem cells are considered the origin of neoplasms in general, and malignant tumours in particular, and the stage at which the stem cells stop their…”
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Activation of REG family proteins in colitis by Granlund, Atle Van Beelen, Beisvag, Vidar, Torp, Sverre H., Flatberg, Arnar, Kleveland, Per Martin, Østvik, Ann Elisabeth, Waldum, Helge L., Sandvik, Arne K.

“…Abstract Aims. To do a genome-wide gene expression study of active and inactive ulcerative colitis and Crohn's disease (inflammatory bowel disease - IBD) and…”
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Decreased bone mineral density and reduced bone quality in H+/K+ATPase beta-subunit deficient mice by Fossmark, Reidar, Stunes, Astrid K., Petzold, Christiane, Waldum, Helge L., Rubert, Marina, Lian, Aina-Mari, Reseland, Janne E., Syversen, Unni

“…Proton pump inhibitors (PPIs) are widely used against gastroesophageal reflux disease. Recent epidemiological studies suggest that PPI users have an increased…”
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Reflections after 10 years as Editor, including 8 years as Editor-in-Chief in Scandinavian Journal of Gastroenterology by Waldum, Helge L.

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Clinical consequences of controversies in gastric physiology by Waldum, Helge L.

“…Studies on the regulation of gastric acid secretion started more than 100 years ago at an early phase of experimental physiology. In nearly the whole last…”
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