Search Results - "Waldron, Todd J."

IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment by Karakasheva, Tatiana A, Lin, Eric W, Tang, Qiaosi, Qiao, Edmund, Waldron, Todd J, Soni, Monica, Klein-Szanto, Andres J, Sahu, Varun, Basu, Devraj, Ohashi, Shinya, Baba, Kiichiro, Giaccone, Zachary T, Walker, Sarah R, Frank, David A, Wileyto, E Paul, Long, Qi, Dunagin, Margaret C, Raj, Arjun, Diehl, J Alan, Wong, K K, Bass, Adam J, Rustgi, Anil K

“…The tumor microenvironment (TME) plays a major role in the pathogenesis of multiple cancer types, including upper-gastrointestinal (GI) cancers that currently…”
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CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer by Karakasheva, Tatiana A, Waldron, Todd J, Eruslanov, Evgeniy, Kim, Sang-Bae, Lee, Ju-Seog, O'Brien, Shaun, Hicks, Philip D, Basu, Devraj, Singhal, Sunil, Malavasi, Fabio, Rustgi, Anil K

“…Myeloid-derived suppressor cells (MDSC) are an immunosuppressive population of immature myeloid cells found in advanced-stage cancer patients and mouse tumor…”
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Deletion of p120-Catenin Results in a Tumor Microenvironment with Inflammation and Cancer that Establishes It as a Tumor Suppressor Gene by Stairs, Douglas B., Bayne, Lauren J., Rhoades, Ben, Vega, Maria E., Waldron, Todd J., Kalabis, Jiri, Klein-Szanto, Andres, Lee, Ju-Seog, Katz, Jonathan P., Diehl, J. Alan, Reynolds, Albert B., Vonderheide, Robert H., Rustgi, Anil K.

“…p120-catenin (p120ctn) interacts with E-cadherin, but to our knowledge, no formal proof that p120ctn functions as a bona fide tumor suppressor gene has emerged…”
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Myeloid derived suppressor cells: Targets for therapy by Waldron, Todd J., Quatromoni, Jon G., Karakasheva, Tatiana A., Singhal, Sunil, Rustgi, Anil K.

“…The goal of achieving measurable response with cancer immunotherapy requires counteracting the immunosuppressive characteristics of tumors. One of the…”
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Optical Imaging of Periostin Enables Early Endoscopic Detection and Characterization of Esophageal Cancer in Mice by Wong, Gabrielle S, Habibollahi, Peiman, Heidari, Pedram, Lee, Ju–Seog, Klein–Szanto, Andres J, Waldron, Todd J, Gimotty, Phyllis, Nakagawa, Hiroshi, Taylor, Philip R, Wang, Timothy C, Mahmood, Umar, Rustgi, Anil K

“…Imaging strategies that detect early stage esophageal squamous cell carcinoma (ESCC) could improve clinical outcomes, when combined with endoscopic approaches…”
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Abstract A32: Il-6 initiates a self-sustaining signaling loop to promote nurturing tumor microenvironment by Karakasheva, Tatiana A., Soni, Monica, Waldron, Todd J., Lin, Eric W., Hicks, Philip D., Klein-Szanto, Andres, Wong, Kwok K., Bass, Adam J., Rustgi, Anil K.

“…Desmoplasia, or deposition of connective tissue proper in the stroma, is a key feature of esophageal squamous cell carcinoma (ESCC), a common malignancy…”
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Abstract 3175: CD38-expressing myeloid-derived suppressor cells promote tumor growth in a murine model of esophageal cancer by Karakasheva, Tatiana A., Waldron, Todd J., Eruslanov, Evgeniy, Lee, Ju-Seog, O'Brien, Shaun, Basu, Devraj, Singhal, Sunil, Malavasi, Fabio, Rustgi, Anil K.

“…Myeloid derived suppressor cells (MDSCs) are an immunosuppressive population of immature myeloid cells found in advanced stage cancer patients and mouse tumor…”
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Abstract 5061: Induction of B cell acute lymphoblastic leukemia by BCR/ABL requires c-Myb and its activation of Bmi-1 by Waldron, Todd J., Soliera, Angele R., Zhang, Ying, Martinez, Robert, Hyslop, Terry, Bender, Timothy, Calabretta, Bruno

“…Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL), carrying the e1a2 fusion BCR/ABL oncogene, is typically an aggressive B cell leukemia,…”
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A role for Myb in BCR-ABL(p190)-induced leukemogenesis: Regulation of Arf suppression through transcriptional activation of BMI1 by Waldron, Todd J

“…Philadelphia chromosome positive acute lymphoblastic leukemia (Ph +-ALL), carrying the e1a2 fusion BCR-ABL oncogene, is typically an aggressive B cell…”
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A role for Myb in BCR-ABL(p190)-induced leukemogenesis: Regulation of Arf suppression through transcriptional activation of BMI1 by Waldron, Todd J

“…Philadelphia chromosome positive acute lymphoblastic leukemia (Ph +-ALL), carrying the e1a2 fusion BCR-ABL oncogene, is typically an aggressive B cell…”
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