Search Results - "Waldorf, Kristina M. Adams"

Perinatal Group B Streptococcal Infections: Virulence Factors, Immunity, and Prevention Strategies by Vornhagen, Jay, Adams Waldorf, Kristina M, Rajagopal, Lakshmi

“…Group B streptococcus (GBS) or Streptococcus agalactiae is a β-hemolytic, Gram-positive bacterium that is a leading cause of neonatal infections. GBS commonly…”
Get full text

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta by Whidbey, Christopher, Harrell, Maria Isabel, Burnside, Kellie, Ngo, Lisa, Becraft, Alexis K, Iyer, Lakshminarayan M, Aravind, L, Hitti, Jane, Adams Waldorf, Kristina M, Rajagopal, Lakshmi

“…Microbial infection of the amniotic fluid is a significant cause of fetal injury, preterm birth, and newborn infections. Group B Streptococcus (GBS) is an…”
Get full text

Bacterial and Host Determinants of Group B Streptococcal Vaginal Colonization and Ascending Infection in Pregnancy by Brokaw, Alyssa, Furuta, Anna, Dacanay, Matthew, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…Group B streptococcus (GBS) is a gram-positive bacteria that asymptomatically colonizes the vaginal tract. However, during pregnancy maternal GBS colonization…”
Get full text

Uterine overdistention induces preterm labor mediated by inflammation: observations in pregnant women and nonhuman primates by Adams Waldorf, Kristina M., MD, Singh, Natasha, MBBS, MRCOG, BSCCP, Mohan, Aarthi R., MD, PhD, Young, Roger C., MD, PhD, Ngo, Lisa, BS, Das, Ananya, MSc, Tsai, Jesse, BS, Bansal, Aasthaa, PhD, Paolella, Louis, BS, Herbert, Bronwen R., BSc, PhD, Sooranna, Suren R., PhD, Gough, G. Michael, MSc, Astley, Cliff, MS, Vogel, Keith, DVM, Baldessari, Audrey E., DVM, Bammler, Theodor K., PhD, MacDonald, James, MSc, Gravett, Michael G., MD, Rajagopal, Lakshmi, PhD, Johnson, Mark R., MD, PhD

“…Objective Uterine overdistention is thought to induce preterm labor in women with twin and multiple pregnancies, but the pathophysiology remains unclear. We…”
Get full text

The Aftermath of Zika: Need for Long-Term Monitoring of Exposed Children by Adams Waldorf, Kristina M., Olson, Erin M., Nelson, Branden R., Little, Marie-Térèse E., Rajagopal, Lakshmi

“…Pregnancy infections with Zika virus are associated with a spectrum of fetal brain injuries beyond microcephaly. Nonmicrocephalic children exposed to Zika…”
Get full text

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term by Lannon, Sophia M. R., Adams Waldorf, Kristina M., Fiedler, Tina, Kapur, Raj P., Agnew, Kathy, Rajagopal, Lakshmi, Gravett, Michael G., Fredricks, David N.

“…Background: The majority of early preterm births are associated with intrauterine infections, which are thought to occur when microbes traffic into the uterus…”
Get full text

Hyaluronidase Impairs Neutrophil Function and Promotes Group B Streptococcus Invasion and Preterm Labor in Nonhuman Primates by Coleman, Michelle, Armistead, Blair, Orvis, Austyn, Quach, Phoenicia, Brokaw, Alyssa, Gendrin, Claire, Sharma, Kavita, Ogle, Jason, Merillat, Sean, Dacanay, Matthew, Wu, Tsung-Yen, Munson, Jeff, Baldessari, Audrey, Vornhagen, Jay, Furuta, Anna, Nguyen, Shayla, Adams Waldorf, Kristina M, Rajagopal, Lakshmi

“…Invasive bacterial infections during pregnancy are a major risk factor for preterm birth, stillbirth, and fetal injury. Group B streptococci (GBS) are…”
Get full text

A Broad Spectrum Chemokine Inhibitor Prevents Preterm Labor but Not Microbial Invasion of the Amniotic Cavity or Neonatal Morbidity in a Non-human Primate Model by Coleman, Michelle, Orvis, Austyn, Wu, Tsung-Yen, Dacanay, Matthew, Merillat, Sean, Ogle, Jason, Baldessari, Audrey, Kretzer, Nicole M, Munson, Jeff, Boros-Rausch, Adam J, Shynlova, Oksana, Lye, Stephen, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…Leukocyte activation within the chorioamniotic membranes is strongly associated with inflammation and preterm labor (PTL). We hypothesized that prophylaxis…”
Get full text

Ultrasound prediction of Zika virus-associated congenital injury using the profile of fetal growth by Walker, Christie L, Ehinger, Noah, Mason, Brittney, Oler, Elizabeth, Little, Marie-Térèse E, Ohuma, Eric O, Papageorghiou, Aris T, Nayeri, Unzila, Curry, Christine, Adams Waldorf, Kristina M

“…Zika virus (ZIKV) is a mosquito-transmitted flavivirus, recently linked to microcephaly and central nervous system anomalies following infection in pregnancy…”
Get full text

A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury by Whidbey, Christopher, Vornhagen, Jay, Gendrin, Claire, Boldenow, Erica, Samson, Jenny Mae, Doering, Kenji, Ngo, Lisa, Ezekwe, Ejiofor A D, Gundlach, Jens H, Elovitz, Michal A, Liggitt, Denny, Duncan, Joseph A, Adams Waldorf, Kristina M, Rajagopal, Lakshmi

“…Group B streptococci (GBS) are Gram‐positive bacteria that cause infections in utero and in newborns. We recently showed that the GBS pigment is hemolytic and…”
Get full text

Mid-trimester amniotic fluid proteome's association with spontaneous preterm delivery and gestational duration by Hallingström, Maria, Zedníková, Petra, Tambor, Vojtěch, Barman, Malin, Vajrychová, Marie, Lenčo, Juraj, Viklund, Felicia, Tancred, Linda, Rabe, Hardis, Jonsson, Daniel, Kachikis, Alisa, Nilsson, Staffan, Kacerovský, Marian, Adams Waldorf, Kristina M, Jacobsson, Bo

“…Amniotic fluid is clinically accessible via amniocentesis and its protein composition may correspond to birth timing. Early changes in the amniotic fluid…”
Get full text

Influence of infection during pregnancy on fetal development by Adams Waldorf, Kristina M, McAdams, Ryan M

“…Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited sequelae depending on the pathogen. Here, we consider the role…”
Get full text

Dramatic enhancement of the detection limits of bioassays via ultrafast deposition of polydopamine by Li, Junwei, Baird, Madison A., Davis, Michael A., Tai, Wanyi, Zweifel, Larry S., Waldorf, Kristina M. Adams, Gale Jr, Michael, Rajagopal, Lakshmi, Pierce, Robert H., Gao, Xiaohu

“…The ability to detect biomarkers with ultrahigh sensitivity radically transformed biology and disease diagnosis. However, owing to incompatibilities with…”
Get full text

Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth by Li, Miranda, Brokaw, Alyssa, Furuta, Anna M, Coler, Brahm, Obregon-Perko, Veronica, Chahroudi, Ann, Wang, Hsuan-Yuan, Permar, Sallie R, Hotchkiss, Charlotte E, Golos, Thaddeus G, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…A wide array of pathogens has the potential to injure the fetus and induce teratogenesis, the process by which mutations in fetal somatic cells lead to…”
Get full text

Impact of Infections During Pregnancy on Transplacental Antibody Transfer by Coler, Celeste, King-Nakaoka, Elana, Every, Emma, Chima, Sophia, Vong, Ashley, Del Rosario, Briana, VanAbel, Roslyn, Adams Waldorf, Kristina M

“…Vaccination in pregnancy is important to protect the mother and fetus from infectious diseases. The transfer of maternal antibodies across the placenta during…”
Get full text

The fetal origins of mental illness by al-Haddad, Benjamin J.S., Oler, Elizabeth, Armistead, Blair, Elsayed, Nada A., Weinberger, Daniel R., Bernier, Raphael, Burd, Irina, Kapur, Raj, Jacobsson, Bo, Wang, Caihong, Mysorekar, Indira, Rajagopal, Lakshmi, Adams Waldorf, Kristina M.

“…The impact of infections and inflammation during pregnancy on the developing fetal brain remains incompletely defined, with important clinical and research…”
Get full text

A structured review of placental morphology and histopathological lesions associated with SARS-CoV-2 infection by Sharps, Megan C., Hayes, Dexter J.L., Lee, Stacey, Zou, Zhiyong, Brady, Chloe A., Almoghrabi, Yousef, Kerby, Alan, Tamber, Kajal K., Jones, Carolyn J., Adams Waldorf, Kristina M., Heazell, Alexander E.P.

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, was first identified after a cluster of cases in Wuhan, China in…”
Get full text

Virulence, phenotype and genotype characteristics of invasive group B Streptococcus isolates obtained from Swedish pregnant women and neonates by Huebner, Emily M, Gudjónsdóttir, Margrét Johansson, Dacanay, Matthew B, Nguyen, Shayla, Brokaw, Alyssa, Sharma, Kavita, Elfvin, Anders, Hentz, Elisabet, Rivera, Ysabella Raceli, Burd, Nicole, Shivakumar, Megana, Coler, Brahm, Li, Miranda, Li, Amanda, Munson, Jeff, Orvis, Austyn, Coleman, Michelle, Jacobsson, Bo, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…Group B streptococci (GBS) are bacteria that can cause preterm birth and invasive neonatal disease. Heterogeneous expression of virulence factors enables GBS…”
Get full text

Group B streptococcal infection of the choriodecidua induces dysfunction of the cytokeratin network in amniotic epithelium: a pathway to membrane weakening by Vanderhoeven, Jeroen P, Bierle, Craig J, Kapur, Raj P, McAdams, Ryan M, Beyer, Richard P, Bammler, Theo K, Farin, Federico M, Bansal, Aasthaa, Spencer, Min, Deng, Mei, Gravett, Michael G, Rubens, Craig E, Rajagopal, Lakshmi, Adams Waldorf, Kristina M

“…Early events leading to intrauterine infection remain poorly defined, but may hold the key to preventing preterm delivery. To determine molecular pathways…”
Get full text

A Mother's Dilemma: The 5-P Model for Vaccine Decision-Making in Pregnancy by Cox, Elizabeth, Sanchez, Magali, Taylor, Katherine, Baxter, Carly, Crary, Isabelle, Every, Emma, Futa, Brianne, Adams Waldorf, Kristina M

“…Pregnant women are a highly vaccine-resistant population and face unique circumstances that complicate vaccine decision-making. Pregnant women are also at…”
Get full text